Directed evolution of pyruvate decarboxylase-negative Saccharomyces cerevisiae, yielding a C2-independent, glucose-tolerant, and pyruvate-hyperproducing yeast. (Q40468284)

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scientific article published on January 2004

Language	Label	Description	Also known as
English	Directed evolution of pyruvate decarboxylase-negative Saccharomyces cerevisiae, yielding a C2-independent, glucose-tolerant, and pyruvate-hyperproducing yeast.	scientific article published on January 2004

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scholarly article

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17 November 2019

Directed evolution of pyruvate decarboxylase-negative Saccharomyces cerevisiae, yielding a C2-independent, glucose-tolerant, and pyruvate-hyperproducing yeast (English)

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17 November 2019

directed evolution

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Saccharomyces cerevisiae

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based on heuristic

inferred from title

Matthew D Piper

6

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17 November 2019

8

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17 November 2019

author name string

Antonius J A van Maris

1

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17 November 2019

Jan-Maarten A Geertman

2

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17 November 2019

Alexander Vermeulen

3

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17 November 2019

Matthijs K Groothuizen

4

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17 November 2019

Aaron A Winkler

5

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17 November 2019

Johannes P van Dijken

7

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17 November 2019

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1 January 2004

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17 November 2019

Applied and Environmental Microbiology

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17 November 2019

70

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17 November 2019

1

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17 November 2019

159-166

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17 November 2019

Experiments with the Chemostat on spontaneous mutations of bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

22 September 2017

Description of the chemostat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

22 September 2017

Modulating the distribution of fluxes among respiration and fermentation by overexpression of HAP4 in Saccharomyces cerevisiae.

1 reference

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22 September 2017

Glucose-sensing and -signalling mechanisms in yeast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

22 September 2017

Overproduction of threonine aldolase circumvents the biosynthetic role of pyruvate decarboxylase in glucose-limited chemostat cultures of Saccharomyces cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

22 September 2017

Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method

1 reference

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22 September 2017

Metabolic engineering of glycerol production in Saccharomyces cerevisiae

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22 September 2017

Auxotrophic yeast strains in fundamental and applied research.

1 reference

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Evolutionary engineering of industrially important microbial phenotypes

1 reference

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22 September 2017

Biotechnological production of pyruvic acid

1 reference

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Significance analysis of microarrays applied to the ionizing radiation response

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22 September 2017

Physiological properties of Saccharomyces cerevisiae from which hexokinase II has been deleted

1 reference

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22 September 2017

Adaptive mutation: implications for evolution

1 reference

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22 September 2017

Redirection of the respiro-fermentative flux distribution in Saccharomyces cerevisiae by overexpression of the transcription factor Hap4p

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

22 September 2017

Metabolic engineering of Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

22 September 2017

Molecular characterization of carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria in Saccharomyces cerevisiae and identification of a plasma membrane carnitine transporter, Agp2p

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

22 September 2017

Investigation of the impact of MIG1 and MIG2 on the physiology of Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

22 September 2017

Yeast carbon catabolite repression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

22 September 2017

Effects of pyruvate decarboxylase overproduction on flux distribution at the pyruvate branch point in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

22 September 2017

Metabolic responses of pyruvate decarboxylase-negative Saccharomyces cerevisiae to glucose excess

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

22 September 2017

The GLY1 gene of Saccharomyces cerevisiae encodes a low-specific L-threonine aldolase that catalyzes cleavage of L-allo-threonine and L-threonine to glycine--expression of the gene in Escherichia coli and purification and characterization of the enzy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

22 September 2017

Growth and metabolism of Saccharomyces cerevisiae in chemostat cultures under carbon-, nitrogen-, or carbon- and nitrogen-limiting conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

22 September 2017

The mutation DGT1-1 decreases glucose transport and alleviates carbon catabolite repression in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

22 September 2017

Genetic analysis of the pyruvate decarboxylase reaction in yeast glycolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

22 September 2017

Selection in chemostats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

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New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

22 September 2017

Characterization of PDC6, a third structural gene for pyruvate decarboxylase in Saccharomyces cerevisiae

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

22 September 2017

https://pubmed.ncbi.nlm.nih.gov/14711638

12 December 2020

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inferred from PubMed ID database lookup

Regulation of the yeast CYT1 gene encoding cytochrome c1 by HAP1 and HAP2/3/4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

22 September 2017

Heterologous protein production in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

22 September 2017

A review. Microbial selection in continuous culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

22 September 2017

Pyruvate metabolism in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

25 September 2017

Reproducibility of oligonucleotide microarray transcriptome analyses. An interlaboratory comparison using chemostat cultures of Saccharomyces cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

17 June 2018

Yeast HAP2 and HAP3 activators both bind to the CYC1 upstream activation site, UAS2, in an interdependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

17 June 2018

Effects of a hexokinase II deletion on the dynamics of glycolysis in continuous cultures of Saccharomyces cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

20 August 2018

The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321313

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20 August 2018

An interlaboratory comparison of physiological and genetic properties of four Saccharomyces cerevisiae strains

1 reference

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The HAP2,3,4 transcriptional activator is required for derepression of the yeast citrate synthase gene, CIT1.

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1 reference

https://pubmed.ncbi.nlm.nih.gov/14711638

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Pyruvate decarboxylase: an indispensable enzyme for growth of Saccharomyces cerevisiae on glucose

1 reference

https://pubmed.ncbi.nlm.nih.gov/14711638

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Development of metabolically engineered Saccharomyces cerevisiae cells for the production of lactic acid

1 reference

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Steady-state and transient-state analysis of growth and metabolite production in a Saccharomyces cerevisiae strain with reduced pyruvate-decarboxylase activity

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Regulation of fermentative capacity and levels of glycolytic enzymes in chemostat cultures of Saccharomyces cerevisiae

1 reference

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Effect of benzoic acid on metabolic fluxes in yeasts: a continuous-culture study on the regulation of respiration and alcoholic fermentation

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1 reference

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/14711638

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AEM.70.1.159-166.2004

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17 November 2019

PMC publication ID

1 reference

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17 November 2019

PubMed publication ID

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17 November 2019

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