The phosphatase DUSP2 controls the activity of the transcription activator STAT3 and regulates TH17 differentiation (Q40417033)

20 September 2017

title

The phosphatase DUSP2 controls the activity of the transcription activator STAT3 and regulates TH17 differentiation (English)

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20 September 2017

1

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5 June 2020

author name string

Liang Liu

2

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5 June 2020

Xin Ji

3

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5 June 2020

Yanan Gao

4

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5 June 2020

Xi Chen

5

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5 June 2020

Yu Liu

6

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5 June 2020

Yang Liu

7

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5 June 2020

Xuyang Zhao

8

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5 June 2020

Yan Li

9

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5 June 2020

Yunqiao Li

10

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Yan Jin

11

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5 June 2020

Yu Zhang

12

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5 June 2020

Michael A McNutt

13

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5 June 2020

Yuxin Yin

14

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5 June 2020

language of work or name

English

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publication date

19 October 2015

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20 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26479789 AND SRC:MED&resulttype=core&format=json

5 June 2020

volume

16

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5 June 2020

issue

12

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5 June 2020

page(s)

1263-1273

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26479789 AND SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

21 January 2018

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STAT3 regulates cytokine-mediated generation of inflammatory helper T cells

21 January 2018

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Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

21 January 2018

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CD4 regulatory T cells control TH17 responses in a Stat3-dependent manner.

21 January 2018

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Inflammatory bowel disease

21 January 2018

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Signal transducers and activators of transcription 3 signaling pathway: an essential mediator of inflammatory bowel disease and other forms of intestinal inflammation

21 January 2018

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Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

21 January 2018

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Genome-wide association identifies multiple ulcerative colitis susceptibility loci

21 January 2018

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Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis.

21 January 2018

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Jak-STAT signaling induced by the v-abl oncogene

21 January 2018

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Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner

21 January 2018

1 reference

Dual-specificity phosphatases 2: surprising positive effect at the molecular level and a potential biomarker of diseases

21 January 2018

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Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses.

21 January 2018

1 reference

Signaling by the phosphatase MKP-1 in dendritic cells imprints distinct effector and regulatory T cell fates

21 January 2018

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Dusp5 negatively regulates IL-33-mediated eosinophil survival and function

21 January 2018

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DUSP4 deficiency enhances CD25 expression and CD4 T-cell proliferation without impeding T-cell development

21 January 2018

1 reference

PAC-1: a Mitogen-Induced Nuclear Protein Tyrosine Phosphatase

21 January 2018

1 reference

PAC1 phosphatase is a transcription target of p53 in signalling apoptosis and growth suppression

21 January 2018

1 reference

PAC1 is a direct transcription target of E2F-1 in apoptotic signaling

21 January 2018

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The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation

21 January 2018

1 reference

Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1.

21 January 2018

1 reference

Histone H3 as a novel substrate for MAP kinase phosphatase-1.

21 January 2018

1 reference

JNK pathway-associated phosphatase dephosphorylates focal adhesion kinase and suppresses cell migration.

21 January 2018

1 reference

Chemically induced mouse models of intestinal inflammation

21 January 2018

1 reference

T cell transfer model of chronic colitis: concepts, considerations, and tricks of the trade

21 January 2018

1 reference

Induction and molecular signature of pathogenic TH17 cells

21 January 2018

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Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

21 January 2018

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The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF

21 January 2018

1 reference

Solution structure of the MAPK phosphatase PAC-1 catalytic domain. Insights into substrate-induced enzymatic activation of MKP

21 January 2018

2 references

21 January 2018

12 December 2020

Suppression of dual-specificity phosphatase–2 by hypoxia increases chemoresistance and malignancy in human cancer cells

1 reference

Increased inflammation and lethality of Dusp1-/- mice in polymicrobial peritonitis models.

21 January 2018

1 reference

Protein tyrosine phosphatases in autoimmunity.

21 January 2018

1 reference

Regulation of innate and adaptive immune responses by MAP kinase phosphatase 5

21 January 2018

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IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner

21 January 2018

1 reference

Cytokines in inflammatory bowel disease

21 January 2018

1 reference

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17 T helper cells

21 January 2018

1 reference

Distinct cytokine patterns identified from multiplex profiles of murine DSS and TNBS-induced colitis

21 January 2018

1 reference

Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity.

21 January 2018

1 reference

CREB is a novel nuclear target of PTEN phosphatase

21 January 2018

1 reference

The tumor-suppressive function of UNC5D and its repressed expression in renal cell carcinoma

21 January 2018

1 reference

IκBζ regulates TH17 development by cooperating with ROR nuclear receptors

21 January 2018

1 reference

IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation

21 January 2018

1 reference

12 December 2020

The phosphatase JKAP/DUSP22 inhibits T-cell receptor signalling and autoimmunity by inactivating Lck

1 reference

12 December 2020

Dual-specificity phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation.

1 reference

12 December 2020

Constitutive STAT3 Activation in Intestinal T Cells from Patients with Crohn's Disease

1 reference

12 December 2020

Identifiers

DOI

10.1038/NI.3278

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26479789 AND SRC:MED&resulttype=core&format=json

5 June 2020

1 reference