FasL (CD95L/APO-1L) resistance of neurons mediated by phosphatidylinositol 3-kinase-Akt/protein kinase B-dependent expression of lifeguard/neuronal membrane protein 35. (Q40395370)

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scientific article published on July 2005

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English	FasL (CD95L/APO-1L) resistance of neurons mediated by phosphatidylinositol 3-kinase-Akt/protein kinase B-dependent expression of lifeguard/neuronal membrane protein 35.	scientific article published on July 2005

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31 December 2019

FasL (CD95L/APO-1L) resistance of neurons mediated by phosphatidylinositol 3-kinase-Akt/protein kinase B-dependent expression of lifeguard/neuronal membrane protein 35 (English)

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31 December 2019

membrane protein

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Andreas Krueger

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Jörg B. Schulz

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Ueli Suter

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Matthias Endres

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Matthias Endres

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31 December 2019

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Christoph P Beier

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Marc Gleichmann

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31 December 2019

Ellen Gerhardt

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31 December 2019

Ana Pekanovic

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31 December 2019

Verdon Taylor

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31 December 2019

Peter H Krammer

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31 December 2019

Jörg Wischhusen

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31 December 2019

Michael Weller

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1 July 2005

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31 December 2019

Journal of Neuroscience

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31 December 2019

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31 December 2019

6765-6774

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31 December 2019

Fas/Apo [apoptosis]-1 and associated proteins in the differentiating cerebral cortex: induction of caspase-dependent cell death and activation of NF-kappaB

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FasL (CD95L, Apo1L) is expressed in the normal rat and human brain: evidence for the existence of an immunological brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective up-regulation of phosphatidylinositol 3'-kinase activity in Th2 cells inhibits caspase-8 cleavage at the death-inducing complex: a mechanism for Th2 resistance from Fas-mediated apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LFG: an anti-apoptotic gene that provides protection from Fas-mediated cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Programmed cell death of embryonic motoneurons triggered through the Fas death receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular survival: a play in three Akts

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fast, convenient, and effective method to transiently transfect primary hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fas/CD95/APO-1 can function as a death receptor for neuronal cells in vitro and in vivo and is upregulated following cerebral hypoxic-ischemic injury to the developing rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor-1-mediated protection from neuronal apoptosis is linked to phosphorylation of the pro-apoptotic protein BAD but not to inhibition of cytochrome c translocation in rat cerebellar neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A noncommercial dual luciferase enzyme assay system for reporter gene analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-kinase activity in murine motoneuron disease: the progressive motor neuropathy mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cascade of caspase activation in potassium-deprived cerebellar granule neurons: targets for treatment with peptide and protein inhibitors of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3'-kinase blocks CD95 aggregation and caspase-8 cleavage at the death-inducing signaling complex by modulating lateral diffusion of CD95

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-kinase/Akt signaling controls endothelial cell sensitivity to Fas-mediated apoptosis via regulation of FLICE-inhibitory protein (FLIP).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic neutralization of CD95-ligand and TNF attenuates brain damage in stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of Fas expression by STAT3 and c-Jun is mediated by phosphatidylinositol 3-kinase-AKT signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of Fas ligand in immune privilege

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of phosphorylation of Akt and neuronal survival after transient focal cerebral ischemia in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A system for stable expression of short interfering RNAs in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of inhibitor-of-differentiation 2 (Id2) as a modulator of neuronal apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FKHRL1 and its homologs are new targets of nerve growth factor Trk receptor signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of neuronal density and subfield sizes in the hippocampus of CD95L-deficient (gld), CD95-deficient (lpr) and nondeficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the Rb/E2F1 pathway by the nonproliferative p38 MAPK during Fas (APO1/CD95)-mediated neuronal apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of Bcl-2-associated death protein and counter-response of Akt within cell populations during seizure-induced neuronal death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neural membrane protein 35/Lifeguard is localized at postsynaptic sites and in dendrites

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Canstatin inhibits Akt activation and induces Fas-dependent apoptosis in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of Fas receptor is required for the increased formation of the disialoganglioside GD3 in cultured cerebellar granule cells committed to apoptotic death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoimmune lymphoproliferative syndrome with somatic Fas mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inherited Perforin andFasMutations in a Patient with Autoimmune Lymphoproliferative Syndrome and Lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-Fas/APO-1 antibody-mediated apoptosis of cultured human glioma cells. Induction and modulation of sensitivity by cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fas/APO-1 gene transfer for human malignant glioma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local Fas/APO-1 (CD95) ligand-mediated tumor cell killing in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fas gene mutations in the Canale-Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fas ligand expression by astrocytoma in vivo: maintaining immune privilege in the brain?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of phosphatidylinositol 3-kinase activity blocks depolarization- and insulin-like growth factor I-mediated survival of cerebellar granule cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of death receptor signals by cellular FLIP

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fas- and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection of CD95-mediated apoptosis by activation of phosphatidylinositide 3-kinase and protein kinase B

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A DEVD-inhibited caspase other than CPP32 is involved in the commitment of cerebellar granule neurons to apoptosis induced by K deprivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neural membrane protein 35 (NMP35): a novel member of a gene family which is highly expressed in the adult nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of fas antigen in the normal mouse brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of phosphatidylinositol 3-kinase activity elevates c-Jun N-terminal kinase activity in apoptosis of cultured cerebellar granule neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of c-FLIP in modulation of CD95-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16033886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.1700-05.2005

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31 December 2019

PMC publication ID

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Europe PubMed Central

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31 December 2019

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16033886 AND SRC:MED&resulttype=core&format=json

31 December 2019

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