Early endosome antigen 1 (Q4037784)

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mammalian protein found in Homo sapiens
  • zinc finger FYVE domain-containing protein 2
  • EEA1
  • endosome-associated protein p162
  • early endosome antigen 1, 162kD
  • early endosome antigen 1
  • early endosome-associated protein
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Language Label Description Also known as
English
Early endosome antigen 1
mammalian protein found in Homo sapiens
  • zinc finger FYVE domain-containing protein 2
  • EEA1
  • endosome-associated protein p162
  • early endosome antigen 1, 162kD
  • early endosome antigen 1
  • early endosome-associated protein

Statements

molecular function
protein binding
determination method or standard
IPI
14 references
retrieved
8 April 2019
stated in
The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking
GOA
curator
UniProt
UniProt protein ID
Q15075
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IPI
retrieved
8 April 2019
stated in
EEA1 links PI(3)K function to Rab5 regulation of endosome fusion
GOA
curator
UniProt
UniProt protein ID
Q15075
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IPI
retrieved
8 April 2019
stated in
Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7
GOA
curator
UniProt
UniProt protein ID
Q15075
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IPI
retrieved
8 April 2019
stated in
The Rab5 effector EEA1 interacts directly with syntaxin-6
GOA
curator
UniProt
UniProt protein ID
Q15075
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IPI
retrieved
8 April 2019
stated in
Direct interaction of EEA1 with Rab5b
GOA
curator
UniProt
UniProt protein ID
Q15075
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IPI
retrieved
8 April 2019
stated in
The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IPI
retrieved
8 April 2019
stated in
Membrane targeting and activation of the Lowe syndrome protein OCRL1 by rab GTPases
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IPI
retrieved
8 April 2019
stated in
EEA1 links PI(3)K function to Rab5 regulation of endosome fusion
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IPI
retrieved
8 April 2019
stated in
Endofin Recruits TOM1 to Endosomes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IPI
retrieved
8 April 2019
stated in
Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IPI
retrieved
8 April 2019
stated in
The Rab5 effector EEA1 interacts directly with syntaxin-6
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IPI
retrieved
8 April 2019
stated in
Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IPI
retrieved
8 April 2019
stated in
An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IPI
retrieved
8 April 2019
stated in
Direct interaction of EEA1 with Rab5b
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IPI
cell component
early endosome
determination method or standard
IDA
IEA
TAS
13 references
retrieved
8 April 2019
stated in
EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
TAS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IEA
retrieved
8 April 2019
stated in
Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies
GOA
curator
UniProt
UniProt protein ID
Q15075
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IDA
retrieved
8 April 2019
stated in
Multivalent endosome targeting by homodimeric EEA1
GOA
curator
UniProt
UniProt protein ID
Q15075
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IDA
retrieved
8 April 2019
stated in
SNX12 role in endosome membrane transport
GOA
curator
UniProt
UniProt protein ID
Q15075
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IDA
retrieved
8 April 2019
stated in
Transferrin receptor co-localizes and interacts with the hemochromatosis factor (HFE) and the divalent metal transporter-1 (DMT1) in trophoblast cells
GOA
curator
UniProt
UniProt protein ID
Q15075
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IDA
retrieved
8 April 2019
stated in
Regulation of divalent metal transporter expression in human intestinal epithelial cells following exposure to non-haem iron
GOA
curator
UniProt
UniProt protein ID
Q15075
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IDA
retrieved
8 April 2019
stated in
Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IDA
retrieved
8 April 2019
stated in
Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles ...
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IDA
retrieved
8 April 2019
stated in
Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IDA
retrieved
8 April 2019
stated in
Printor, a novel torsinA-interacting protein implicated in dystonia pathogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IDA
retrieved
8 April 2019
stated in
Palmitoyl protein thioesterase 1 (PPT1) deficiency causes endocytic defects connected to abnormal saposin processing
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IDA
retrieved
8 April 2019
stated in
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15075
determination method or standard
IDA
biological process

Identifiers

 
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