Inhibition of Akt/PKB by a COX-2 inhibitor induces apoptosis in gastric cancer cells. (Q40287095)

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20 January 2020

title

Inhibition of Akt/PKB by a COX-2 inhibitor induces apoptosis in gastric cancer cells (English)

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Xiaohua Jiang

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author name string

Xiao Ming Fan

1

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Qing Gu

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Yick Pang Ching

4

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Harry H X Xia

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Marie Chia Mi Lin

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Annie O O Chan

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Man Fung Yuen

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Hsiang-Fu Kung

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Benjamin Chun-Yu Wong

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publication date

19 April 2006

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volume

73

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issue

2-3

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page(s)

75-83

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

20 January 2020

cites work

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Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

21 January 2018

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The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

21 January 2018

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Novel target for induction of apoptosis by cyclo-oxygenase-2 inhibitor SC-236 through a protein kinase C-beta(1)-dependent pathway

21 January 2018

1 reference

Suppression of RelA/p65 nuclear translocation independent of IkappaB-alpha degradation by cyclooxygenase-2 inhibitor in gastric cancer

21 January 2018

1 reference

Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway.

21 January 2018

1 reference

Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt

21 January 2018

1 reference

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

1 reference

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)

21 January 2018

1 reference

Akt signaling: linking membrane events to life and death decisions

21 January 2018

1 reference

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

21 January 2018

1 reference

Akt-dependent and -independent survival signaling pathways utilized by insulin-like growth factor I.

21 January 2018

1 reference

The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2

21 January 2018

1 reference

Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

21 January 2018

1 reference

Cyclooxygenase, NSAIDs, and colorectal cancer

21 January 2018

1 reference

NSAID use and decreased risk of gastrointestinal cancers

21 January 2018

1 reference

Aspirin, NSAIDS, and colon cancer prevention: mechanisms?

21 January 2018

1 reference

Growth inhibition and induction of apoptosis in colorectal tumor cells by cyclooxygenase inhibitors

21 January 2018

1 reference

Non-steroidol anti-inflammatory drug effect on crypt cell proliferation and apoptosis during initiation of rat colon carcinogenesis

21 January 2018

1 reference

Cyclooxygenase regulates angiogenesis induced by colon cancer cells

21 January 2018

1 reference

Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing

21 January 2018

1 reference

Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts

21 January 2018

1 reference

The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis

21 January 2018

1 reference

Celecoxib induces apoptosis by inhibiting 3-phosphoinositide-dependent protein kinase-1 activity in the human colon cancer HT-29 cell line

21 January 2018

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Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

21 January 2018

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Modulation of Akt kinase activity by binding to Hsp90

21 January 2018

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Mitochondria and apoptosis

21 January 2018

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Non-steroidal anti-inflammatory drugs induce apoptosis in gastric cancer cells through up-regulation of bax and bak

21 January 2018

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Akt regulates cell survival and apoptosis at a postmitochondrial level

21 January 2018

1 reference

Mechanisms and consequences of activation of protein kinase B/Akt

21 January 2018

1 reference

Elevated AKT activity protects the prostate cancer cell line LNCaP from TRAIL-induced apoptosis

21 January 2018

1 reference

Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer

21 January 2018

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Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1159/000092747

1 reference

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release_fqqkdmbmqzernla345j7awd4ga

20 January 2020

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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