A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells. (Q40285464)

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20 January 2020

title

A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells (English)

1 reference

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1

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https://orcid.org/0000-0002-3457-3320

Rune Hartmann

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20 January 2020

Mark A. Behlke

8

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Bryan Williams

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author name string

Thalie Devosse

2

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20 January 2020

Die Wang

3

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Maryam Zamanian-Daryoush

4

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Paul Serbinowski

5

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Takashi Fujita

7

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publication date

30 April 2006

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volume

24

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issue

5

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page(s)

559-565

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Activation of the mammalian immune system by siRNAs.

20 January 2020

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Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase

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Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3.

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Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs).

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Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy

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IRF-3-dependent, NFkappa B- and JNK-independent activation of the 561 and IFN-beta genes in response to double-stranded RNA

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A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA.

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Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

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An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection

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Characterization of the solution complex between the interferon-induced, double-stranded RNA-activated protein kinase and HIV-I trans-activating region RNA.

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Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA

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