Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia. (Q40280788)

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21 January 2020

title

Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia (English)

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21 January 2020

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1

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21 January 2020

author name string

Mahfoud Assem

2

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21 January 2020

Jessica C Tay

3

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21 January 2020

Paul B Watkins

4

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21 January 2020

Bruce Blumberg

5

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21 January 2020

Erin G Schuetz

6

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21 January 2020

Kenneth E Thummel

7

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21 January 2020

language of work or name

English

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publication date

11 May 2006

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Journal of Clinical Investigation

21 January 2020

published in

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21 January 2020

volume

116

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21 January 2020

issue

6

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21 January 2020

page(s)

1703-1712

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Intestinal and hepatic CYP3A4 catalyze hydroxylation of 1alpha,25-dihydroxyvitamin D(3): implications for drug-induced osteomalacia

21 January 2020

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Possible involvement of pregnane X receptor-enhanced CYP24 expression in drug-induced osteomalacia

22 September 2017

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2-Methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 potently stimulates gene-specific DNA binding of the vitamin D receptor in osteoblasts

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Regulation of 25-hydroxyvitamin D3-24-hydroxylase mRNA by 1,25-dihydroxyvitamin D3 and parathyroid hormone

22 September 2017

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22 September 2017

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Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocytes.

22 September 2017

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22 September 2017

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22 September 2017

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

22 September 2017

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Enzymatic studies on the key enzymes of vitamin D metabolism; 1 alpha-hydroxylase (CYP27B1) and 24-hydroxylase (CYP24).

22 September 2017

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The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

22 September 2017

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22 September 2017

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22 September 2017

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25 September 2017

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1,25-Dihydroxyvitamin D3 stimulates cyclic vitamin D receptor/retinoid X receptor DNA-binding, co-activator recruitment, and histone acetylation in intact osteoblasts

20 August 2018

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20 August 2018

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20 August 2018

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Antiepileptic drug-induced bone loss in young male patients who have seizures

20 August 2018

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Osteomalacia associated with carbamazepine/valproate

20 August 2018

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12 December 2020

The influence of phenobarbital on biotransformation of 25-hydroxycholecalciferol

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12 December 2020

Rifampicin induced osteomalacia

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12 December 2020

Expression of the 1,25-dihydroxyvitamin D3-24-hydroxylase gene in rat intestine: response to calcium, vitamin D3 and calcitriol administration in vivo

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12 December 2020

Comparative in vivo expression of the calcitriol-24-hydroxylase gene in kidney and intestine

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12 December 2020

Differential time course of induction of 1alpha,25-dihydroxyvitamin D3-24-hydroxylase mRNA expression in rats by 1alpha,25-dihydroxyvitamin D3 and its analogs

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12 December 2020

Identifiers

DOI

10.1172/JCI27793

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16691293 AND SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16691293 AND SRC:MED&resulttype=core&format=json

21 January 2020

PubMed publication ID

16691293

1 reference