Mre11-Rad50-Nbs1 complex is activated by hypertonicity. (Q40264840)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16788144 AND SRC:MED&resulttype=core&format=json

25 December 2019

title

Mre11-Rad50-Nbs1 complex is activated by hypertonicity (English)

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25 December 2019

3

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25 December 2019

author name string

Mee Rie Sheen

1

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25 December 2019

Seung Whan Kim

2

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25 December 2019

Joon Young Ahn

4

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25 December 2019

Juong G Rhee

5

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25 December 2019

H Moo Kwon

6

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25 December 2019

Seung Kyoon Woo

7

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25 December 2019

publication date

20 June 2006

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American Journal of Physiology - Renal Physiology

25 December 2019

published in

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25 December 2019

volume

291

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25 December 2019

issue

5

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25 December 2019

page(s)

F1014-20

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

25 December 2019

cites work

1 reference

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Initiating cellular stress responses

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The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

21 January 2018

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Retroviral expression of the NBS1 gene in cultured Nijmegen breakage syndrome cells restores normal radiation sensitivity and nuclear focus formation

21 January 2018

1 reference

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Hypertonic stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPRENAL.00153.2006

High NaCl causes Mre11 to leave the nucleus, disrupting DNA damage signaling and repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPRENAL.00153.2006

Cells adapted to high NaCl have many DNA breaks and impaired DNA repair both in cell culture and in vivo

21 January 2018

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Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

21 January 2018

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ATM, a DNA damage-inducible kinase, contributes to activation by high NaCl of the transcription factor TonEBP/OREBP.

21 January 2018

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The many substrates and functions of ATM

21 January 2018

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Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway

21 January 2018

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Hyperosmolality in the form of elevated NaCl but not urea causes DNA damage in murine kidney cells

21 January 2018

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Hyperosmolality causes growth arrest of murine kidney cells. Induction of GADD45 and GADD153 by osmosensing via stress-activated protein kinase 2.

21 January 2018

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A general protocol for evaluating the specific effects of DNA replication inhibitors

21 January 2018

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ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

21 January 2018

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DNA damage checkpoint and repair centers

21 January 2018

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DNA damage-dependent nuclear dynamics of the Mre11 complex

21 January 2018

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Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity

21 January 2018

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Heat Shock Factor-1 and the Heat Shock Cognate 70 Protein Associate in High Molecular Weight Complexes in the Cytoplasm of NIH-3T3 Cells

21 January 2018

1 reference

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The Mre11 complex and ATM: collaborating to navigate S phase

21 January 2018

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High urea and NaCl carbonylate proteins in renal cells in culture and in vivo, and high urea causes 8-oxoguanine lesions in their DNA

21 January 2018

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