PRIMA-1(MET) induces nucleolar accumulation of mutant p53 and PML nuclear body-associated proteins (Q40243688)

18 September 2017

title

PRIMA-1(MET) induces nucleolar accumulation of mutant p53 and PML nuclear body-associated proteins (English)

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18 September 2017

N Rökaeus

1

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18 September 2017

G Klein

2

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18 September 2017

K G Wiman

3

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18 September 2017

L Szekely

4

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18 September 2017

K Mattsson

5

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18 September 2017

language of work or name

English

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publication date

14 August 2006

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18 September 2017

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18 September 2017

volume

26

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18 September 2017

issue

7

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18 September 2017

page(s)

982-992

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Histone deacetylase inhibitors induce caspase-dependent apoptosis and downregulation of daxx in acute promyelocytic leukaemia with t(15;17).

18 September 2017

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Accumulation of c-Myc and proteasomes at the nucleoli of cells containing elevated c-Myc protein levels

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c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription.

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PML regulates p53 stability by sequestering Mdm2 to the nucleolus

21 January 2018

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Regulation and localization of the Bloom syndrome protein in response to DNA damage

21 January 2018

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Deconstructing PML-induced premature senescence

21 January 2018

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Mutant p53-dependent growth suppression distinguishes PRIMA-1 from known anticancer drugs: a statistical analysis of information in the National Cancer Institute database.

21 January 2018

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Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

21 January 2018

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Reactivation of mutant p53 and induction of apoptosis in human tumor cells by maleimide analogs.

21 January 2018

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PRIMA-1(MET) synergizes with cisplatin to induce tumor cell apoptosis.

21 January 2018

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p53 is a general repressor of RNA polymerase III transcription

21 January 2018

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PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA.

21 January 2018

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Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.

21 January 2018

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Identification of PML oncogenic domains (PODs) in human megakaryocytes

21 January 2018

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DNA viruses and viral proteins that interact with PML nuclear bodies

21 January 2018

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A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein

21 January 2018

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Cooperation between the RING B1-B2 and coiled-coil domains of PML is necessary for its effects on cell survival.

21 January 2018

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Regulation of p53 activity in nuclear bodies by a specific PML isoform

21 January 2018

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The function of PML in p53-dependent apoptosis

21 January 2018

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Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2

21 January 2018

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Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation

21 January 2018

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Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence

21 January 2018

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Analysis of the growth and transformation suppressor domains of promyelocytic leukemia gene, PML.

21 January 2018

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Sequestration and inhibition of Daxx-mediated transcriptional repression by PML

21 January 2018

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Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization

21 January 2018

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The promyelocytic leukemia protein protects p53 from Mdm2-mediated inhibition and degradation

21 January 2018

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The IARC TP53 database: new online mutation analysis and recommendations to users

21 January 2018

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The moving parts of the nucleolus

21 January 2018

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Atmospheric carbon dioxide concentrations over the past 60 million years

21 January 2018

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In vivo stress preconditioning

21 January 2018

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Proteasome inhibitor induces nucleolar translocation of Epstein-Barr virus-encoded EBNA-5.

21 January 2018

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Role and fate of PML nuclear bodies in response to interferon and viral infections

21 January 2018

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Proteomic identification of heat shock protein 90 as a candidate target for p53 mutation reactivation by PRIMA-1 in breast cancer cells

21 January 2018

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Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses

21 January 2018

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Does the ribosome translate cancer?

21 January 2018

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The role of PML in tumor suppression

21 January 2018

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P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

21 January 2018

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Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolus

21 January 2018

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Live or let die: the cell's response to p53

21 January 2018

1 reference

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PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209858

Repression of RNA polymerase I transcription by the tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209858

The transcriptional role of PML and the nuclear body

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209858

Pharmacological rescue of mutant p53 conformation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209858

inferred from DOI database lookup

7 January 2021

based on heuristic

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209858

inferred from DOI database lookup

7 January 2021

based on heuristic

PML is essential for multiple apoptotic pathways

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209858

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1209858

1 reference

Dimensions Publication ID

18 September 2017

1034032525

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1 reference