The COP9 signalosome regulates Skp2 levels and proliferation of human cells. (Q40237851)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16943200 AND SRC:MED&resulttype=core&format=json

29 December 2019

title

The COP9 signalosome regulates Skp2 levels and proliferation of human cells (English)

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Maria Elena Fernandez Sanchez

29 December 2019

author

2

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29 December 2019

Lars Rogge

3

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29 December 2019

author name string

Simona Denti

1

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29 December 2019

Elisabetta Bianchi

4

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29 December 2019

language of work or name

English

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publication date

30 August 2006

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Journal of Biological Chemistry

29 December 2019

published in

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29 December 2019

volume

281

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29 December 2019

issue

43

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29 December 2019

page(s)

32188-32196

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29 December 2019

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

The COP9 signalosome is essential for development of Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Neddylation and deneddylation of CUL-3 is required to target MEI-1/Katanin for degradation at the meiosis-to-mitosis transition in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex

21 January 2018

1 reference

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The Ins(1,3,4)P3 5/6-kinase/Ins(3,4,5,6)P4 1-kinase is not a protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Fission yeast COP9/signalosome suppresses cullin activity through recruitment of the deubiquitylating enzyme Ubp12p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

The zinc finger of the CSN-associated deubiquitinating enzyme USP15 is essential to rescue the E3 ligase Rbx1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

The NED-8 conjugating system in Caenorhabditis elegans is required for embryogenesis and terminal differentiation of the hypodermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

NEDD8 recruits E2-ubiquitin to SCF E3 ligase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

The COP9 signalosome inhibits p27(kip1) degradation and impedes G1-S phase progression via deneddylation of SCF Cul1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

The COP9 Signalosome Promotes Degradation of Cyclin E during Early Drosophila Oogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Radiation-mediated proteolysis of CDT1 by CUL4–ROC1 and CSN complexes constitutes a new checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Ddb1 is required for the proteolysis of the Schizosaccharomyces pombe replication inhibitor Spd1 during S phase and after DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Disruption of the COP9 signalosome Csn2 subunit in mice causes deficient cell proliferation, accumulation of p53 and cyclin E, and early embryonic death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

COP9 signalosome: a multifunctional regulator of SCF and other cullin-based ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

COP9 signalosome revisited: a novel mediator of protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

The COP9 signalosome: an assembly and maintenance platform for cullin ubiquitin ligases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

CSN facilitates Cullin-RING ubiquitin ligase function by counteracting autocatalytic adapter instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

The COP9 signalosome regulates the Neurospora circadian clock by controlling the stability of the SCFFWD-1 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

COP9 signalosome subunit 3 is essential for maintenance of cell proliferation in the mouse embryonic epiblast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Multiple functions of Jab1 are required for early embryonic development and growth potential in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Integrin LFA-1 interacts with the transcriptional co-activator JAB1 to modulate AP-1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Arabidopsis COP9 is a component of a novel signaling complex mediating light control of development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Evidence for FUS6 as a component of the nuclear-localized COP9 complex in Arabidopsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Deregulated degradation of the cdk inhibitor p27 and malignant transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Targeted silencing of Jab1/Csn5 in human cells downregulates SCF activity through reduction of F-box protein levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Ubiquitin-dependent degradation of multiple F-box proteins by an autocatalytic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Stability of homologue of Slimb F-box protein is regulated by availability of its substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Involvement of CUL4 ubiquitin E3 ligases in regulating CDK inhibitors Dacapo/p27Kip1 and cyclin E degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Cul4A and DDB1 associate with Skp2 to target p27Kip1 for proteolysis involving the COP9 signalosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

The cytoplasmic shuttling and subsequent degradation of p27Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

COP9 signalosome-directed c-Jun activation/stabilization is independent of JNK

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Loss of the CONSTITUTIVE PHOTOMORPHOGENIC9 signalosome subunit 5 is sufficient to cause the cop/det/fus mutant phenotype in Arabidopsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Growth suppression induced by the TRC8 hereditary kidney cancer gene is dependent upon JAB1/CSN5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Small Jab1-containing subcomplex is regulated in an anchorage- and cell cycle-dependent manner, which is abrogated by ras transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

Interactions of the COP9 Signalosome with the E3 Ubiquitin Ligase SCFTIR1 in Mediating Auxin Response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M604746200

21 January 2018

Identifiers

DOI

10.1074/JBC.M604746200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16943200 AND SRC:MED&resulttype=core&format=json

29 December 2019

1 reference