Modulation of the functional binding sites for TGF-beta on the type II receptor leads to suppression of TGF-beta signaling (Q40200583)

18 September 2017

title

Modulation of the functional binding sites for TGF-beta on the type II receptor leads to suppression of TGF-beta signaling (English)

1 reference

18 September 2017

Shimanuki T

1

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18 September 2017

Hara T

2

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18 September 2017

Furuya T

3

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18 September 2017

Imamura T

4

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18 September 2017

Miyazono K

5

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18 September 2017

language of work or name

English

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publication date

4 December 2006

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18 September 2017

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18 September 2017

volume

26

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18 September 2017

issue

23

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18 September 2017

page(s)

3311-3320

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Structure of the ternary signaling complex of a TGF-beta superfamily member

18 September 2017

cites work

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Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin

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Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily

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Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase.

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TGF-beta signaling in tumor suppression and cancer progression

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Regulated expression of P210 Bcr-Abl during embryonic stem cell differentiation stimulates multipotential progenitor expansion and myeloid cell fate

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Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor

21 January 2018

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Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling

21 January 2018

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A flexible activin explains the membrane-dependent cooperative assembly of TGF-beta family receptors

21 January 2018

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Identification of a functional binding site for activin on the type I receptor ALK4

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TGF-β signalling from cell membrane to nucleus through SMAD proteins

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Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2

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Morin inhibits 12-O-tetradecanoylphorbol-13-acetate-induced hepatocellular transformation via activator protein 1 signaling pathway and cell cycle progression

21 January 2018

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Smad6 inhibits signalling by the TGF-β superfamily

21 January 2018

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Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors

21 January 2018

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Flavopiridol, the first cyclin-dependent kinase inhibitor to enter the clinic: current status

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Crystal structure of the BMP-2-BRIA ectodomain complex

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Betaglycan presents ligand to the TGF beta signaling receptor.

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The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding

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Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis

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An unusual feature revealed by the crystal structure at 2.2 A resolution of human transforming growth factor-beta 2

21 January 2018

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Phase II study of the cyclin-dependent kinase inhibitor flavopiridol administered to patients with advanced gastric carcinoma.

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Flavopiridol: the first cyclin-dependent kinase inhibitor in human clinical trials

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Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions

21 January 2018

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The ALK-5 inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-beta

21 January 2018

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Three key residues underlie the differential affinity of the TGFbeta isoforms for the TGFbeta type II receptor

21 January 2018

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Binding affinity of transforming growth factor-beta for its type II receptor is determined by the C-terminal region of the molecule

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210123

inferred from DOI database lookup

7 January 2021

based on heuristic

Distinct functional domains of TGF-beta bind receptors on endothelial cells

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210123

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1210123

1 reference

Dimensions Publication ID

18 September 2017

1001441453

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1 reference