Flt-1, but not Flk-1 mediates hyperpermeability through activation of the PI3-K/Akt pathway (Q40169031)

18 September 2017

title

Flt-1, but not Flk-1 mediates hyperpermeability through activation of the PI3-K/Akt pathway (English)

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18 September 2017

4

Klaus T Preissner

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18 September 2017

Carsten Vogel

1

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18 September 2017

Alexander Bauer

2

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18 September 2017

Marion Wiesnet

3

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18 September 2017

Wolfgang Schaper

5

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18 September 2017

Hugo H Marti

6

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18 September 2017

Silvia Fischer

7

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18 September 2017

publication date

1 July 2007

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Journal of Cellular Physiology

18 September 2017

published in

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18 September 2017

volume

212

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18 September 2017

issue

1

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18 September 2017

page(s)

236-243

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Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1

18 September 2017

cites work

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Neuropilin-1 regulates vascular endothelial growth factor-mediated endothelial permeability.

21 January 2018

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IGF-I neuroprotection in the immature brain after hypoxia-ischemia, involvement of Akt and GSK3beta?

21 January 2018

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Activation of vascular endothelial growth factor receptor-1 sustains angiogenesis and Bcl-2 expression via the phosphatidylinositol 3-kinase pathway in endothelial cells

21 January 2018

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Placenta growth factor: identification and characterization of a novel isoform generated by RNA alternative splicing

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Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis

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Culture and Characterization of Epithelial Cells from Bovine Choroid Plexus

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Structure and function of placental growth factor

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The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

21 January 2018

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Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

21 January 2018

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Mechanisms and consequences of activation of protein kinase B/Akt

21 January 2018

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Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells

21 January 2018

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The biology of VEGF and its receptors

21 January 2018

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Simultaneous activation of several second messengers in hypoxia-induced hyperpermeability of brain derived endothelial cells

21 January 2018

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H2O2 induces paracellular permeability of porcine brain-derived microvascular endothelial cells by activation of the p44/42 MAP kinase pathway

21 January 2018

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Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

21 January 2018

1 reference

Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner

21 January 2018

1 reference

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

21 January 2018

1 reference

Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia.

21 January 2018

1 reference

Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

21 January 2018

1 reference

Expression and prognostic relevance of vascular endothelial growth factor (VEGF) and its receptor (FLT-1) in nephroblastoma.

21 January 2018

1 reference

Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants

21 January 2018

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Brain edema in meningiomas is associated with increased vascular endothelial growth factor expression.

21 January 2018

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Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells.

21 January 2018

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Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

21 January 2018

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Signal transduction by VEGF receptor-1 wild type and mutant proteins

21 January 2018

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A recombinant mutant vascular endothelial growth factor-C that has lost vascular endothelial growth factor receptor-2 binding, activation, and vascular permeability activities

21 January 2018

1 reference

Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor

21 January 2018

1 reference

Neuropilin-1 binds vascular endothelial growth factor 165, placenta growth factor-2, and heparin via its b1b2 domain

21 January 2018

1 reference

Identification of regulatory sites of phosphorylation of the bovine endothelial nitric-oxide synthase at serine 617 and serine 635.

21 January 2018

1 reference

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

21 January 2018

1 reference

Vascular endothelial growth factor-A, vascular endothelial growth factor receptor-2 and angiopoietin-2 expression in the mouse choroid plexuses

21 January 2018

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A novel type of vascular endothelial growth factor, VEGF-E (NZ-7 VEGF), preferentially utilizes KDR/Flk-1 receptor and carries a potent mitotic activity without heparin-binding domain

21 January 2018

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Vascular endothelial growth factor upregulates pigment epithelium-derived factor expression via VEGFR-1 in human retinal pigment epithelial cells

21 January 2018

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Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth

21 January 2018

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Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium

21 January 2018

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Differential binding characteristics and cellular inhibition by soluble VEGF receptors 1 and 2.

21 January 2018

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Hypoxia-induced vascular endothelial growth factor expression causes vascular leakage in the brain

21 January 2018

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Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid

21 January 2018

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Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

21 January 2018

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Structure and function of VEGF/VEGF-receptor system involved in angiogenesis

21 January 2018

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A mutant form of vascular endothelial growth factor (VEGF) that lacks VEGF receptor-2 activation retains the ability to induce vascular permeability

21 January 2018

1 reference

Potential role of IGF-I in hypoxia tolerance using a rat hypoxic-ischemic model: activation of hypoxia-inducible factor 1alpha

21 January 2018

1 reference

Vascular endothelial growth factor receptor-1 promotes migration and invasion in pancreatic carcinoma cell lines

21 January 2018

1 reference

Vascular endothelial growth factor (VEGF)-like protein from orf virus NZ2 binds to VEGFR2 and neuropilin-1

21 January 2018

1 reference

Flt-1-mediated down-regulation of endothelial cell proliferation through pertussis toxin-sensitive G proteins, beta gamma subunits, small GTPase CDC42, and partly by Rac-1.

21 January 2018

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VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.21022

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release_v4kran2vqjbnpkk7ktgwiefhaq

18 September 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/v4kran2vqjbnpkk7ktgwiefhaq

mapped directly with Wikidata item

24 November 2022

based on heuristic

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