A new binding motif for the transcriptional repressor REST uncovers large gene networks devoted to neuronal functions. (Q40117288)

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1 January 2020

title

A new binding motif for the transcriptional repressor REST uncovers large gene networks devoted to neuronal functions (English)

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author name string

Stefanie J Otto

1

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1 January 2020

Sean R McCorkle

2

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1 January 2020

John Hover

3

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1 January 2020

Cecilia Conaco

4

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Jong-Jin Han

5

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1 January 2020

Soren Impey

6

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1 January 2020

Gregory S Yochum

7

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John J Dunn

8

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Richard H Goodman

9

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Gail Mandel

10

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language of work or name

English

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publication date

1 June 2007

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1 January 2020

published in

Journal of Neuroscience

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volume

27

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issue

25

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page(s)

6729-6739

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A splice variant of the neuron-restrictive silencer factor repressor is expressed in small cell lung cancer: a potential role in derepression of neuroendocrine genes and a useful clinical marker

1 January 2020

cites work

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12 December 2020

The neuron-restrictive silencer element-neuron-restrictive silencer factor system regulates basal and endothelin 1-inducible atrial natriuretic peptide gene expression in ventricular myocytes

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12 December 2020

Regulation of neuronal traits by a novel transcriptional complex

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Fibronectin signaling stimulates BNP gene transcription by inhibiting neuron-restrictive silencer element-dependent repression

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Using the transcriptome to annotate the genome

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Protocadherin LKC, a new candidate for a tumor suppressor of colon and liver cancers, its association with contact inhibition of cell proliferation

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Molecular characterization of a metastatic neuroendocrine cell cancer arising in the prostates of transgenic mice

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Corepressor-dependent silencing of chromosomal regions encoding neuronal genes

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Reduced expression of the neuron restrictive silencer factor permits transcription of glycine receptor alpha1 subunit in small-cell lung cancer cells

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12 December 2020

NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function

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12 December 2020

Interaction of the repressor element 1-silencing transcription factor (REST) with target genes

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12 December 2020

Relaxation of glycine receptor and onconeural gene transcription control in NRSF deficient small cell lung cancer cell lines

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12 December 2020

Conversion of myoblasts to physiologically active neuronal phenotype

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12 December 2020

Localized domains of G9a-mediated histone methylation are required for silencing of neuronal genes

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12 December 2020

Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes

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Defining the CREB regulon: a genome-wide analysis of transcription factor regulatory regions.

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Identification of the mismatch repair genes PMS2 and MLH1 as p53 target genes by using serial analysis of binding elements

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Mapping DNA-protein interactions in large genomes by sequence tag analysis of genomic enrichment

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12 December 2020

REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis.

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A human- and male-specific protocadherin that acts through the wnt signaling pathway to induce neuroendocrine transdifferentiation of prostate cancer cells.

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12 December 2020

A genetic screen for candidate tumor suppressors identifies REST

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12 December 2020

Transcriptional regulation: cancer, neurons and the REST

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12 December 2020

Distinct profiles of REST interactions with its target genes at different stages of neuronal development

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12 December 2020

Downregulated REST transcription factor is a switch enabling critical potassium channel expression and cell proliferation

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12 December 2020

A global map of p53 transcription-factor binding sites in the human genome

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12 December 2020

The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells

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Protocadherin-PC promotes androgen-independent prostate cancer cell growth.

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12 December 2020

Interchromosomal interactions and olfactory receptor choice

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12 December 2020

Identification of the REST regulon reveals extensive transposable element-mediated binding site duplication

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12 December 2020

A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells

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12 December 2020

Comparative genomics modeling of the NRSF/REST repressor network: from single conserved sites to genome-wide repertoire

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12 December 2020

Comparative sequence analysis reveals an intricate network among REST, CREB and miRNA in mediating neuronal gene expression

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12 December 2020

Global mapping of c-Myc binding sites and target gene networks in human B cells

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12 December 2020

REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons

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12 December 2020

The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes

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12 December 2020

Identification of potential target genes for the neuron-restrictive silencer factor

1 reference

12 December 2020

The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

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12 December 2020

The neural restrictive silencer element can act as both a repressor and enhancer of L1 cell adhesion molecule gene expression during postnatal development

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12 December 2020

Base-calling of automated sequencer traces using phred. II. Error probabilities

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12 December 2020

Incorporation of adenovirus in calcium phosphate precipitates enhances gene transfer to airway epithelia in vitro and in vivo

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12 December 2020

NRSF/REST is required in vivo for repression of multiple neuronal target genes during embryogenesis

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12 December 2020

10.1523/JNEUROSCI.0091-07.2007

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17581960 AND SRC:MED&resulttype=core&format=json

1 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17581960 AND SRC:MED&resulttype=core&format=json

1 January 2020

PubMed publication ID

17581960

1 reference