Stress via p53 pathway causes apoptosis by mitochondrial Noxa upregulation in doxorubicin-treated neuroblastoma cells (Q40102569)

17 September 2017

title

Stress via p53 pathway causes apoptosis by mitochondrial Noxa upregulation in doxorubicin-treated neuroblastoma cells (English)

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17 September 2017

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Kurata K

1

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17 September 2017

Yanagisawa R

2

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17 September 2017

Ohira M

3

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17 September 2017

Kitagawa M

4

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17 September 2017

Nakagawara A

5

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17 September 2017

Kamijo T

6

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17 September 2017

language of work or name

English

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publication date

20 August 2007

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17 September 2017

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17 September 2017

volume

27

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17 September 2017

issue

6

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17 September 2017

page(s)

741-754

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Nuclear factor-(kappa)B modulates the p53 response in neurons exposed to DNA damage.

17 September 2017

cites work

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

The role of MYCN in the failure of MYCN amplified neuroblastoma cell lines to G1 arrest after DNA damage

21 January 2018

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Cell death: critical control points

21 January 2018

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Apoptotic pathways: paper wraps stone blunts scissors

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

Doxorubicin-induced death in neuroblastoma does not involve death receptors in S-type cells and is caspase-independent in N-type cells

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to determine cell fate.

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

Requirement for HDM2 activity in the rapid degradation of p53 in neuroblastoma

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

Noxa is a critical mediator of p53-dependent motor neuron death after nerve injury in adult mouse

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

Nitric oxide inhibition of homocysteine-induced human endothelial cell apoptosis by down-regulation of p53-dependent Noxa expression through the formation of S-nitrosohomocysteine

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

Increased expression of proapoptotic BMCC1, a novel gene with the BNIP2 and Cdc42GAP homology (BCH) domain, is associated with favorable prognosis in human neuroblastomas

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

Cytoplasmic sequestration of wild-type p53 protein impairs the G1 checkpoint after DNA damage

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

ARF Tumor Suppressor Induces Mitochondria-dependent Apoptosis by Modulation of Mitochondrial Bcl-2 Family Proteins

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

FKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

Regulation of the p53 tumor suppressor protein

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

p53-dependent apoptosis pathways.

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

Integral role of Noxa in p53-mediated apoptotic response

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

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The p53 pathway and its inactivation in neuroblastoma.

21 January 2018

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Mutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arsenite

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

Evidence that wild-type p53 in neuroblastoma cells is in a conformation refractory to integration into the transcriptional complex

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

BOK and NOXA are essential mediators of p53-dependent apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

Peak plasma concentrations of doxorubicin in children with acute lymphoblastic leukemia or non-Hodgkin lymphoma

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

7 January 2021

Molecular cloning and characterization of a cDNA for a novel phorbol-12-myristate-13-acetate-responsive gene that is highly expressed in an adult T-cell leukemia cell line

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210672

7 January 2021

p53 status and the efficacy of cancer therapy in vivo

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https://api.crossref.org/works/10.1038/SJ.ONC.1210672

7 January 2021

Successful treatment of stage III neuroblastoma based on prospective biologic staging: a Children's Cancer Group study

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210672

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210672

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Dimensions Publication ID

17 September 2017

1024160588

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