Synergistic antiproliferative effects of gamma-tocotrienol and statin treatment on mammary tumor cells (Q40093390)

17 September 2017

title

Synergistic antiproliferative effects of gamma-tocotrienol and statin treatment on mammary tumor cells (English)

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17 September 2017

Vikram B Wali

1

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17 September 2017

Paul W Sylvester

series ordinal

2

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17 September 2017

publication date

14 August 2007

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17 September 2017

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17 September 2017

volume

42

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17 September 2017

issue

12

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17 September 2017

page(s)

1113-1123

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Effects of statins and farnesyltransferase inhibitors on the development and progression of cancer

17 September 2017

cites work

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12 December 2020

Antiproliferative and apoptotic effects of tocopherols and tocotrienols on preneoplastic and neoplastic mouse mammary epithelial cells

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12 December 2020

Lovastatin-induced apoptosis in human melanoma cell lines

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12 December 2020

Phase I study of lovastatin, an inhibitor of the mevalonate pathway, in patients with cancer.

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12 December 2020

gamma-Tocotrienol inhibits ErbB3-dependent PI3K/Akt mitogenic signalling in neoplastic mammary epithelial cells

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12 December 2020

Proapoptotic and antitumor activities of the HMG-CoA reductase inhibitor, lovastatin, against Dalton's lymphoma ascites tumor in mice.

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12 December 2020

Antiproliferative and apoptotic effects of tocopherols and tocotrienols on normal mouse mammary epithelial cells

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12 December 2020

Targeting the mevalonate pathway inhibits the function of the epidermal growth factor receptor

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12 December 2020

Tocotrienols potentiate lovastatin-mediated growth suppression in vitro and in vivo

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12 December 2020

Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase

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12 December 2020

Gamma-tocotrienol inhibits neoplastic mammary epithelial cell proliferation by decreasing Akt and nuclear factor kappaB activity

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12 December 2020

Epidermal growth factor receptor-targeted therapy potentiates lovastatin-induced apoptosis in head and neck squamous cell carcinoma cells

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12 December 2020

Lovastatin inhibits tumor growth and lung metastasis in mouse mammary carcinoma model: a p53-independent mitochondrial-mediated apoptotic mechanism

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12 December 2020

Quantitation of the synergistic interaction of edatrexate and cisplatin in vitro

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12 December 2020

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

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12 December 2020

Relation of cholesterol and mevalonic acid to the cell cycle in smooth muscle and swiss 3T3 cells stimulated to divide by platelet-derived growth factor

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12 December 2020

Fatty acid modulation of epidermal growth factor-induced mouse mammary epithelial cell proliferation in vitro.

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12 December 2020

Suppression of murine neuroblastoma growth in vivo by mevinolin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

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12 December 2020

Inhibitory effects on lipid metabolism in cultured cells of ML-236B, a potent inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme-A reductase

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12 December 2020

Phosphatidylinositol-3-OH kinase as a direct target of Ras

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12 December 2020

Role of caspase-8 activation in mediating vitamin E-induced apoptosis in murine mammary cancer cells

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12 December 2020

Relationship between mevalonate and mitogenesis in human fibroblasts stimulated with platelet-derived growth factor

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12 December 2020

Simvastatin induces apoptosis in human breast cancer cells: p53 and estrogen receptor independent pathway requiring signalling through JNK.

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12 December 2020

The dual role of mevalonate in the cell cycle

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12 December 2020

Effect of statins combined with estradiol on the proliferation of human receptor-positive and receptor-negative breast cancer cells

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12 December 2020

Structural mechanism for statin inhibition of HMG-CoA reductase

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12 December 2020

p21ras is modified by a farnesyl isoprenoid

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12 December 2020

Simvastatin, an inhibitor of cholesterol biosynthesis, shows a synergistic effect with N,N'-bis(2-chloroethyl)-N-nitrosourea and beta-interferon on human glioma cells.

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12 December 2020

Cerivastatin demonstrates enhanced antitumor activity against human breast cancer cell lines when used in combination with doxorubicin or cisplatin.

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12 December 2020

Regulation of HMG-CoA reductase in MCF-7 cells by genistein, EPA, and DHA, alone and in combination with mevastatin

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12 December 2020

Statins can inhibit proliferation of human breast cancer cells in vitro

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12 December 2020

Effect of inhibition of cholesterol synthetic pathway on the activation of Ras and MAP kinase in mesangial cells

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12 December 2020

c-Jun N-terminal protein kinase signalling pathway mediates lovastatin-induced rat brain neuroblast apoptosis

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12 December 2020

Fluvastatin synergistically enhances the antiproliferative effect of gemcitabine in human pancreatic cancer MIAPaCa-2 cells.

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12 December 2020

Farnesyl and geranylgeranyl transferase inhibitors induce G1 arrest by targeting the proteasome.

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12 December 2020

Breast cancer growth prevention by statins

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12 December 2020

Action of lovastatin, simvastatin, and pravastatin on sterol synthesis and their antiproliferative effect in cultured myoblasts from human striated muscle

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12 December 2020

Caspase-7 is activated during lovastatin-induced apoptosis of the prostate cancer cell line LNCaP

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12 December 2020

Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

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12 December 2020

Selection and characterization in culture of mammary tumor cells with distinctive growth properties in vivo

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12 December 2020

Tocotrienol-induced caspase-8 activation is unrelated to death receptor apoptotic signaling in neoplastic mammary epithelial cells.

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12 December 2020

HMG-CoA reductase inhibitor-induced L6 myoblast cell death: involvement of the phosphatidylinositol 3-kinase pathway

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12 December 2020

Role of GTP-binding proteins in reversing the antiproliferative effects of tocotrienols in preneoplastic mammary epithelial cells

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12 December 2020

Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase

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12 December 2020

10.1007/S11745-007-3102-0

Identifiers

DOI

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17 September 2017

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