Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection (Q40042407)

9 July 2018

title

Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection (English)

1 reference

9 July 2018

11

Steven G Deeks

1 reference

9 July 2018

13

Ulf Dittmer

1 reference

9 July 2018

Merlin L Robb

9

Merlin L Robb

1 reference

9 July 2018

Nelson Michael

12

Nelson L Michael

1 reference

9 July 2018

Hendrik Streeck

14

Hendrik Streeck

1 reference

9 July 2018

Galit Alter

8

Galit Alter

1 reference

9 July 2018

Mary A Marovich

5

Mary Marovich

1 reference

9 July 2018

Michael A Eller

3

Michael A Eller

1 reference

9 July 2018

Diane L Bolton

4

Diane L Bolton

1 reference

9 July 2018

Aljawharah Alrubayyi

7

Aljawharah Alrubayyi

1 reference

9 July 2018

Jeffrey E Teigler

1

Jeffrey E Teigler

1 reference

9 July 2018

author name string

Gennadiy Zelinskyy

2

1 reference

9 July 2018

Alexander D Gordon

6

1 reference

9 July 2018

Jeffrey N Martin

10

1 reference

9 July 2018

language of work or name

English

0 references

publication date

14 November 2017

1 reference

9 July 2018

published in

Journal of Virology

1 reference

9 July 2018

volume

91

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9 July 2018

issue

23

1 reference

9 July 2018

Comprehensive Mass Cytometry Analysis of Cell Cycle, Activation, and Coinhibitory Receptors Expression in CD4 T Cells from Healthy and HIV-Infected Individuals

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10 July 2018

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Differential impact of PD-1 and/or interleukin-10 blockade on HIV-1-specific CD4 T cell and antigen-presenting cell functions

10 July 2018

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Combining regulatory T cell depletion and inhibitory receptor blockade improves reactivation of exhausted virus-specific CD8 T cells and efficiently reduces chronic retroviral loads

10 July 2018

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Liver environment and HCV replication affect human T-cell phenotype and expression of inhibitory receptors

10 July 2018

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Association of HLA-DRB1-restricted CD4⁺ T cell responses with HIV immune control

10 July 2018

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A randomized, double-blind, placebo-controlled assessment of BMS-936558, a fully human monoclonal antibody to programmed death-1 (PD-1), in patients with chronic hepatitis C virus infection

10 July 2018

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PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells

10 July 2018

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At the bedside: CTLA-4- and PD-1-blocking antibodies in cancer immunotherapy

10 July 2018

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Involvement of CD244 in regulating CD4 T cell immunity in patients with active tuberculosis

10 July 2018

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Strength of PD-1 signaling differentially affects T-cell effector functions.

10 July 2018

1 reference

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Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production

10 July 2018

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Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice.

10 July 2018

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Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection.

10 July 2018

1 reference

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Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Inhibitory Receptors on Lymphocytes: Insights from Infections

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Expanding roles for CD4⁺ T cells in immunity to viruses.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

HIV-Specific CD4 T Cell Responses to Different Viral Proteins Have Discordant Associations with Viral Load and Clinical Outcome

10 July 2018

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Virus-Specific CD8 T Cells Upregulate Programmed Death-1 Expression during Acute Friend Retrovirus Infection but Are Highly Cytotoxic and Control Virus Replication

10 July 2018

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Tight Regulation of Memory CD8 T Cells Limits Their Effectiveness during Sustained High Viral Load

10 July 2018

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Responsiveness of HIV-specific CD4 T cells to PD-1 blockade

10 July 2018

1 reference

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PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

SPICE: Exploration and analysis of post‐cytometric complex multivariate datasets

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Transient depletion of regulatory T cells in transgenic mice reactivates virus-specific CD8 T cells and reduces chronic retroviral set points

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Cutting edge: TIGIT has T cell-intrinsic inhibitory functions

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Cytolytic CD4 T cells in viral immunity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Tim-3 expression on PD-1 HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

HIV-1-specific interleukin-21 CD4 T cell responses contribute to durable viral control through the modulation of HIV-specific CD8 T cell function

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8 T cells is linked to antigen recognition and T cell differentiation

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Tumor-infiltrating NY-ESO-1-specific CD8 T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

A phase I pharmacokinetic and biological correlative study of IMP321, a novel MHC class II agonist, in patients with advanced renal cell carcinoma

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4 and CD8 T cells

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Synergistic Reversal of Intrahepatic HCV-Specific CD8 T Cell Exhaustion by Combined PD-1/CTLA-4 Blockade

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Coregulation of CD8 T cell exhaustion by multiple inhibitory receptors during chronic viral infection.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

PD-1-dependent mechanisms maintain peripheral tolerance of donor-reactive CD8 T cells to transplanted tissue

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Molecular signature of CD8 T cell exhaustion during chronic viral infection

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Elevated expression levels of inhibitory receptor programmed death 1 on simian immunodeficiency virus-specific CD8 T cells during chronic infection but not after vaccination

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

IL-12 and type-I IFN synergize for IFN-gamma production by CD4 T cells, whereas neither are required for IFN-gamma production by CD8 T cells after Listeria monocytogenes infection

10 July 2018

1 reference

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Programmed cell death 1 ligand 1 and tumor-infiltrating CD8 T lymphocytes are prognostic factors of human ovarian cancer

10 July 2018

1 reference

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PD-1 is a regulator of virus-specific CD8 T cell survival in HIV infection

10 July 2018

1 reference

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PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

10 July 2018

1 reference

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CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms

10 July 2018

1 reference

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Intrinsic functional dysregulation of CD4 T cells occurs rapidly following persistent viral infection

10 July 2018

1 reference

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Molecular basis for positive and negative signaling by the natural killer cell receptor 2B4 (CD244).

10 July 2018

1 reference

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Reduction of retrovirus-induced immunosuppression by in vivo modulation of T cells during acute infection

10 July 2018

1 reference

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Memory CD8 T-cell differentiation during viral infection

10 July 2018

1 reference

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HIV preferentially infects HIV-specific CD4 T cells

10 July 2018

1 reference

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Impairment of Gag-specific CD8( ) T-cell function in mucosal and systemic compartments of simian immunodeficiency virus mac251- and simian-human immunodeficiency virus KU2-infected macaques

10 July 2018

1 reference

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Simian immunodeficiency virus (SIV) infection of a rhesus macaque induces SIV-specific CD8( ) T cells with a defect in effector function that is reversible on extended interleukin-2 incubation

10 July 2018

1 reference

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Functional impairment of simian immunodeficiency virus-specific CD8 T cells during the chronic phase of infection

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Impaired function of circulating HIV-specific CD8( ) T cells in chronic human immunodeficiency virus infection.

10 July 2018

1 reference

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A significant number of human immunodeficiency virus epitope-specific cytotoxic T lymphocytes detected by tetramer binding do not produce gamma interferon

10 July 2018

1 reference

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Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients

10 July 2018

1 reference

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Characterization of a Live-Attenuated Retroviral Vaccine Demonstrates Protection via Immune Mechanisms

10 July 2018

1 reference

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B-tropic Friend virus: a host-range pseudotype of spleen focus-forming virus (SFFV).

10 July 2018

1 reference

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Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes

10 July 2018

1 reference

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Functional Exhaustion of CD4 T Lymphocytes during Primary Cytomegalovirus Infection

10 July 2018

1 reference

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Role of the coinhibitory receptor cytotoxic T lymphocyte antigen-4 on apoptosis-Prone CD8 T cells in persistent hepatitis B virus infection

20 August 2018

1 reference

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The immunoregulatory role of CD244 in chronic hepatitis B infection and its inhibitory potential on virus-specific CD8 T-cell function

20 August 2018

1 reference

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Dynamic programmed death 1 expression by virus-specific CD8 T cells correlates with the outcome of acute hepatitis B.

20 August 2018

1 reference

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Upregulation of CTLA-4 by HIV-specific CD4 T cells correlates with disease progression and defines a reversible immune dysfunction

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Emergence of CTL coincides with clearance of virus during primary simian immunodeficiency virus infection in rhesus monkeys

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Comparison of activation versus induction of unresponsiveness of virus-specific CD4 and CD8 T cells upon acute versus persistent viral infection

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Molecular landscape of T cell-mediated rejection in human kidney transplants: prominence of CTLA4 and PD ligands

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Analysis of the role of negative T cell costimulatory pathways in CD4 and CD8 T cell-mediated alloimmune responses in vivo

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Cytolytic T lymphocyte-associated antigen-4 and the TCR zeta/CD3 complex, but not CD28, interact with clathrin adaptor complexes AP-1 and AP-2

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5686724

Kinetics of CD8 effector T cell responses and induced CD4 regulatory T cell responses during Friend retrovirus infection

4 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28904197

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.01263-17

1 reference

9 July 2018

PMC publication ID

5686724

1 reference

9 July 2018

PubMed publication ID

28904197

1 reference

9 July 2018