Current and future application of genetic toxicity assays: the role and value of in vitro mammalian assays (Q39990800)

16 September 2017

title

Current and future application of genetic toxicity assays: the role and value of in vitro mammalian assays (English)

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16 September 2017

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Rosalie K Elespuru

1

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16 September 2017

Rajiv Agarwal

2

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Aisar H Atrakchi

3

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C Anita H Bigger

4

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Robert H Heflich

5

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Devaraya R Jagannath

6

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Dan D Levy

7

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Martha M Moore

8

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Yanli Ouyang

9

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Timothy W Robison

10

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Rene E Sotomayor

11

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Michael C Cimino

12

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Kerry L Dearfield

13

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publication date

31 March 2009

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16 September 2017

published in

Toxicological Sciences

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volume

109

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issue

2

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page(s)

172-179

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Molecular dissection of mutations at the heterozygous thymidine kinase locus in mouse lymphoma cells

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Genetic toxicity assessment: employing the best science for human safety evaluation. Part II: Performances of the in vitro micronucleus test compared to the mouse lymphoma assay and the in vitro chromosome aberration assay

21 January 2018

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An evaluation of the mode of action framework for mutagenic carcinogens case study: Cyclophosphamide

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Measuring the mitotic index in chemically-treated human lymphocyte cultures by flow cytometry

21 January 2018

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Improving dose selection and identification of aneugens in the in vitro chromosome aberration test by integration of flow cytometry-based methods.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Genetic toxicity assessment: employing the best science for human safety evaluation part III: the comet assay as an alternative to in vitro clastogenicity tests for early drug candidate selection

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/TOXSCI/KFP067

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16 September 2017

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