Serum-free transient protein production system based on adenoviral vector and PER.C6 technology: high yield and preserved bioactivity (Q39977061)

16 September 2017

title

Serum-free transient protein production system based on adenoviral vector and PER.C6 technology: high yield and preserved bioactivity (English)

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16 September 2017

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M J E Havenga

1

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16 September 2017

L Holterman

2

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16 September 2017

I Melis

3

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16 September 2017

S Smits

4

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16 September 2017

J Kaspers

5

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16 September 2017

E Heemskerk

6

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16 September 2017

R van der Vlugt

7

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16 September 2017

M Koldijk

8

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16 September 2017

G J Schouten

9

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16 September 2017

G Hateboer

10

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16 September 2017

K Brouwer

11

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16 September 2017

R Vogels

12

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16 September 2017

J Goudsmit

13

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16 September 2017

publication date

1 June 2008

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Biotechnology and Bioengineering

16 September 2017

published in

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16 September 2017

volume

100

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16 September 2017

issue

2

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16 September 2017

page(s)

273-283

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Genetic engineering of alpha 2,6-sialyltransferase in recombinant CHO cells

16 September 2017

cites work

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Crossref

https://api.crossref.org/works/10.1002/BIT.21757

Introduction, stable integration, and controlled expression of a chimeric adenovirus gene whose product is toxic to the recipient human cell

21 January 2018

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Crossref

https://api.crossref.org/works/10.1002/BIT.21757

Recombinant protein expression for therapeutic applications

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In Vitro and In Vivo Biology of Recombinant Adenovirus Vectors with E1, E1/E2A, or E1/E4 Deleted

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Monoclonal antibodies which recognize native and denatured forms of the adenovirus DNA-binding protein

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Thermolabile DNA binding proteins from cells infected with a temperature-sensitive mutant of adenovrius defective in viral DNA synthesis

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Glycoproteins from insect cells: sialylated or not?

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Recombinant human preproinsulin. Expression, purification and reaction with insulin autoantibodies in sera from patients with insulin-dependent diabetes mellitus.

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Inducible gene expression systems for higher eukaryotic cells

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Trans-complementation of E1-deleted adenovirus: a new vector to reduce the possibility of codissemination of wild-type and recombinant adenoviruses

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Cloning, expression, and crystallization of the fusion protein of Newcastle disease virus

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Isolation and analysis of adenovirus type 5 mutants containing deletions in the gene encoding the DNA-binding protein

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Human monoclonal antibody as prophylaxis for SARS coronavirus infection in ferrets

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Structure and organization of the gene coding for the DNA binding protein of adenovirus type 5

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New helper cells and matched early region 1-deleted adenovirus vectors prevent generation of replication-competent adenoviruses.

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Emergence of early region 1-containing replication-competent adenovirus in stocks of replication-defective adenovirus recombinants (delta E1 delta E3) during multiple passages in 293 cells

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12 December 2020

Generation of an adenovirus vector lacking E1, e2a, E3, and all of E4 except open reading frame 3.

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[Melanin properties studies of the recombinant of Pseudomonas pseudoalcaligenes containing tyrosinase gene]

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High-level expression in mammalian cells of recombinant house dust mite allergen ProDer p 1 with optimized codon usage

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Mammalian cell production of a respiratory syncytial virus (RSV) candidate vaccine recovered using a product-specific affinity column

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Molecular and biological characterization of human monoclonal antibodies binding to the spike and nucleocapsid proteins of severe acute respiratory syndrome coronavirus

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The polypeptides of adenovirus. I. Evidence for multiple protein components in the virion and a comparison of types 2, 7A, and 12

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Improved adenovirus vector provides herpes simplex virus ribonucleotide reductase R1 and R2 subunits very efficiently

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12 December 2020

Serum-free large-scale transient transfection of CHO cells

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12 December 2020

Regulation of mammalian phospholipase D2: interaction with and stimulation by G(M2) activator

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12 December 2020

Genetically engineering mammalian cell lines for increased viability and productivity

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12 December 2020

Genetic optimization of recombinant glycoprotein production by mammalian cells

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12 December 2020

The novel mechanism of initiation of picornavirus RNA translation

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12 December 2020

Production processes of licensed recombinant factor VIII preparations

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12 December 2020

Lack of persistence of E1- recombinant adenoviral vectors containing a temperature-sensitive E2A mutation in immunocompetent mice and hemophilia B dogs

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Recombinant expression of proteoglycans in mammalian cells. Utility and advantages of the vaccinia virus/T7 bacteriophage hybrid expression system

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Parameters influencing the productivity of recombinant E. coli cultivations.

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12 December 2020

Scale-up of recombinant virus and protein production in stirred-tank reactors.

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12 December 2020

Recombinant protein production by large-scale transient gene expression in mammalian cells: state of the art and future perspectives

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Toxicological comparison of E2a-deleted and first-generation adenoviral vectors expressing alpha1-antitrypsin after systemic delivery

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Expression of human placental ribonuclease inhibitor in Escherichia coli

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12 December 2020

High level expression in 293 cells of the herpes simplex virus type 2 ribonucleotide reductase subunit 2 using an adenovirus vector

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12 December 2020

Transient production of recombinant proteins by Chinese hamster ovary cells using polyethyleneimine/DNA complexes in combination with microtubule disrupting anti-mitotic agents

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Characterization of 911: a new helper cell line for the titration and propagation of early region 1-deleted adenoviral vectors.

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Improved glycosylation of a foreign protein by Tn-5B1-4 cells engineered to express mammalian glycosyltransferases.

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Improved adenovirus vectors for infection of cardiovascular tissues

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An adenovirus type 5 gene function required for initiation of viral DNA replication

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12 December 2020

Cloning and expression of human sialic acid pathway genes to generate CMP-sialic acids in insect cells

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12 December 2020

Spider silk fibers spun from soluble recombinant silk produced in mammalian cells

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12 December 2020

Inducible Overexpression of a Toxic Protein by an Adenovirus Vector with a Tetracycline-Regulatable Expression Cassette

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12 December 2020

Selection and preliminary characterization of temperature-sensitive mutants of type 5 adenovirus

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12 December 2020

Detection of wild-type contamination in a recombinant adenoviral preparation by PCR.

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12 December 2020

Spider dragline silk proteins in transgenic tobacco leaves: accumulation and field production

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12 December 2020

Purification and characterization of the monooxygenase catalyzing sulfur-atom specific oxidation of dibenzothiophene and benzothiophene from the thermophilic bacterium Paenibacillus sp. strain A11-2.

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12 December 2020

Post-translational modifications of heterologously expressed cholecystokinin in Saccharomyces cerevisiae.

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12 December 2020

Scale-up of the adenovirus expression system for the production of recombinant protein in human 293S cells

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12 December 2020

Serum-free production of recombinant proteins and adenoviral vectors by 293SF-3F6 cells

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12 December 2020

The production of foreign proteins from genetically modified plant cells.

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12 December 2020

Production of correctly folded Fab antibody fragment in the cytoplasm of Escherichia coli trxB gor mutants via the coexpression of molecular chaperones

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12 December 2020

The production of improved tissue-type plasminogen activator in Escherichia coli

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12 December 2020

Production, purification, and characterization of recombinant 2', 5'-oligoadenylate synthetases

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12 December 2020

Secretion of human proteins from yeast: stimulation by duplication of polyubiquitin and protein disulfide isomerase genes in Kluyveromyces lactis

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12 December 2020

Mammalian glycosyltransferase expression allows sialoglycoprotein production by baculovirus-infected insect cells

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12 December 2020

Structure-activity study of antihypertensive 1,4-dihydropyridine derivatives having nitrooxyalkyl moieties at the 3 and 5 positions

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12 December 2020

Transfer of the CFTR Gene to the Lung of Nonhuman Primates with E1-Deleted, E2a-Defective Recombinant Adenoviruses: A Preclinical Toxicology Study

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12 December 2020

Extrapulmonary manifestations of adenovirus type 7 pneumonia simulating Reye syndrome and the possible role of an adenovirus toxin

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12 December 2020

Identifiers

DOI

10.1002/BIT.21757

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16 September 2017

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