Assembly with the Cul4A-DDB1DCAF1 ubiquitin ligase protects HIV-1 Vpr from proteasomal degradation. (Q39975311)

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8 January 2020

title

Assembly with the Cul4A-DDB1DCAF1 ubiquitin ligase protects HIV-1 Vpr from proteasomal degradation (English)

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8 January 2020

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Florence Margottin-Goguet

7

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8 January 2020

author name string

Erwann Le Rouzic

1

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8 January 2020

Marina Morel

2

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8 January 2020

Diana Ayinde

3

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8 January 2020

Nadia Belaïdouni

4

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8 January 2020

Justine Letienne

5

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Catherine Transy

6

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language of work or name

English

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publication date

4 June 2008

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Journal of Biological Chemistry

8 January 2020

published in

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volume

283

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issue

31

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page(s)

21686-21692

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The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

8 January 2020

cites work

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21 January 2018

1 reference

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Function and regulation of cullin-RING ubiquitin ligases

21 January 2018

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DCAFs, the missing link of the CUL4-DDB1 ubiquitin ligase

21 January 2018

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Viruses and the 26S proteasome: hacking into destruction

21 January 2018

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A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

21 January 2018

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Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex

21 January 2018

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Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle

21 January 2018

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HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system

21 January 2018

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HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase

21 January 2018

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DDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrest

21 January 2018

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The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor

21 January 2018

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HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase

21 January 2018

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Cell cycle arrest by Vpr in HIV-1 virions and insensitivity to antiretroviral agents

21 January 2018

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Human immunodeficiency virus type 1 Vpr induces the degradation of the UNG and SMUG uracil-DNA glycosylases

21 January 2018

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The many faces of beta-TrCP E3 ubiquitin ligases: reflections in the magic mirror of cancer

21 January 2018

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Comparison of cell cycle arrest, transactivation, and apoptosis induced by the simian immunodeficiency virus SIVagm and human immunodeficiency virus type 1 vpr genes.

21 January 2018

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Cytoplasmic retention of HIV-1 regulatory protein Vpr by protein-protein interaction with a novel human cytoplasmic protein VprBP.

21 January 2018

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Regulated degradation of the HIV-1 Vpu protein through a betaTrCP-independent pathway limits the release of viral particles

21 January 2018

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Cellular steady-state levels of "high risk" but not "low risk" human papillomavirus (HPV) E6 proteins are increased by inhibition of proteasome-dependent degradation independent of their p53- and E6AP-binding capabilities

21 January 2018

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Degradation of the retinoblastoma tumor suppressor by the human papillomavirus type 16 E7 oncoprotein is important for functional inactivation and is separable from proteasomal degradation of E7.

21 January 2018

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Human papillomavirus type 16 E7 oncoprotein associates with the cullin 2 ubiquitin ligase complex, which contributes to degradation of the retinoblastoma tumor suppressor

21 January 2018

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The papillomavirus E7 oncoprotein is ubiquitinated by UbcH7 and Cullin 1- and Skp2-containing E3 ligase

21 January 2018

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Catalytic turnover of STAT1 allows PIV5 to dismantle the interferon-induced anti-viral state of cells.

21 January 2018

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Protection of cullin-RING E3 ligases by CSN-UBP12.

21 January 2018

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Vpx association with mature core structures of HIV-2.

21 January 2018

1 reference

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Hepatitis B Virus X Protein and Simian Virus 5 V Protein Exhibit Similar UV-DDB1 Binding Properties To Mediate Distinct Activities

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M710298200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524771 AND SRC:MED&resulttype=core&format=json

8 January 2020

1 reference