TAp73 loss favors Smad-independent TGF-β signaling that drives EMT in pancreatic ductal adenocarcinoma. (Q39947989)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26943320 AND SRC:MED&resulttype=core&format=json

9 March 2020

title

TAp73 loss favors Smad-independent TGF-β signaling that drives EMT in pancreatic ductal adenocarcinoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26943320 AND SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26943320 AND SRC:MED&resulttype=core&format=json

9 March 2020

Laurent Bartholin

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26943320 AND SRC:MED&resulttype=core&format=json

9 March 2020

Fabienne Guillaumond

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26943320 AND SRC:MED&resulttype=core&format=json

9 March 2020

Richard Tomasini

13

1 reference

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9 March 2020

author name string

A K Thakur

1

1 reference

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9 March 2020

S Lac

3

1 reference

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9 March 2020

J Leca

4

1 reference

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9 March 2020

C Bressy

5

1 reference

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9 March 2020

P Berthezene

6

1 reference

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9 March 2020

P Chan

8

1 reference

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9 March 2020

E Calvo

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26943320 AND SRC:MED&resulttype=core&format=json

9 March 2020

J L Iovanna

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26943320 AND SRC:MED&resulttype=core&format=json

9 March 2020

S Vasseur

11

1 reference

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9 March 2020

publication date

4 March 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26943320 AND SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

9 March 2020

published in

1 reference

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9 March 2020

volume

23

1 reference

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9 March 2020

issue

8

1 reference

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9 March 2020

page(s)

1358-1370

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26943320 AND SRC:MED&resulttype=core&format=json

TAp73 suppresses tumor angiogenesis through repression of proangiogenic cytokines and HIF-1α activity

9 March 2020

cites work

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22 September 2017

TAp73 promotes anabolism

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22 September 2017

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22 September 2017

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Inhibitory role of the small leucine-rich proteoglycan biglycan in bladder cancer

22 September 2017

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Overexpression of COL11A1 by cancer-associated fibroblasts: clinical relevance of a stromal marker in pancreatic cancer

22 September 2017

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Genetic and molecular alterations in pancreatic cancer: implications for personalized medicine

22 September 2017

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Nox4-derived ROS signaling contributes to TGF-β-induced epithelial-mesenchymal transition in pancreatic cancer cells

22 September 2017

1 reference

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Correlation of Smad4 status with outcomes in patients receiving erlotinib combined with adjuvant chemoradiation and chemotherapy after resection for pancreatic adenocarcinoma

22 September 2017

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Role of epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma: is tumor budding the missing link?

22 September 2017

1 reference

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Targeting the ERK pathway reduces liver metastasis of Smad4-inactivated colorectal cancer

22 September 2017

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The TP73 complex network: ready for clinical translation in cancer?

22 September 2017

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Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma.

22 September 2017

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Hypoxia induces EMT in low and highly aggressive pancreatic tumor cells but only cells with cancer stem cell characteristics acquire pronounced migratory potential

22 September 2017

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TAp73 is required for macrophage-mediated innate immunity and the resolution of inflammatory responses.

22 September 2017

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Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma.

22 September 2017

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Activated K-Ras and INK4a/Arf deficiency promote aggressiveness of pancreatic cancer by induction of EMT consistent with cancer stem cell phenotype

22 September 2017

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Clinicodemographic aspect of resectable pancreatic cancer and prognostic factors for resectable cancer

22 September 2017

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22 September 2017

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Granzyme B cleaves decorin, biglycan and soluble betaglycan, releasing active transforming growth factor-β1

22 September 2017

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Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma

22 September 2017

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Aurora kinase-A inactivates DNA damage-induced apoptosis and spindle assembly checkpoint response functions of p73

22 September 2017

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p63/p73 in the control of cell cycle and cell death.

22 September 2017

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22 September 2017

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22 September 2017

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An update on molecular research of pancreatic adenocarcinoma

22 September 2017

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p53-dependent regulation of growth, epithelial-mesenchymal transition and stemness in normal pancreatic epithelial cells.

22 September 2017

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Switching TGFβ from a tumor suppressor to a tumor promoter.

22 September 2017

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22 September 2017

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TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity

22 September 2017

1 reference

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Non-Smad pathways in TGF-beta signaling

22 September 2017

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TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

22 September 2017

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22 September 2017

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Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression.

22 September 2017

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Kras(G12D) and Smad4/Dpc4 haploinsufficiency cooperate to induce mucinous cystic neoplasms and invasive adenocarcinoma of the pancreas

22 September 2017

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Genome-wide array-based comparative genomic hybridization analysis of pancreatic adenocarcinoma: identification of genetic indicators that predict patient outcome

22 September 2017

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Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer

22 September 2017

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Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse

22 September 2017

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Adhesion and Rac1-dependent regulation of biglycan gene expression by transforming growth factor-beta. Evidence for oxidative signaling through NADPH oxidase

22 September 2017

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Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads.

22 September 2017

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Characterization of human FAST-1, a TGF beta and activin signal transducer

22 September 2017

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Biglycan is overexpressed in pancreatic cancer and induces G1-arrest in pancreatic cancer cell lines

22 September 2017

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Crosstalk between p53 and TGF-β Signalling.

25 September 2017

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Dynamic Monitoring of Cellular Remodeling Induced by the Transforming Growth Factor-β1.

15 June 2018

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Smad4/DPC4-dependent regulation of biglycan gene expression by transforming growth factor-beta in pancreatic tumor cells

15 June 2018

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Serum transforming growth factor-β1 and risk of pancreatic cancer in three prospective cohort studies

15 June 2018

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The p53 family: guardians of maternal reproduction

20 August 2018

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Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer

20 August 2018

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Epithelial to mesenchymal transition: expression of the regulators snail, slug, and twist in pancreatic cancer.

20 August 2018

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N-cadherin expression and epithelial-mesenchymal transition in pancreatic carcinoma

20 August 2018

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Up-regulated biglycan expression correlates with the malignancy in human colorectal cancers

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26943320

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Sonic hedgehog and Gli1 expression predict outcome in resected pancreatic adenocarcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26943320

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/CDD.2016.18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26943320 AND SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26943320 AND SRC:MED&resulttype=core&format=json

9 March 2020

PubMed publication ID

26943320

1 reference