Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy. (Q39937420)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18806775 AND SRC:MED&resulttype=core&format=json

14 January 2020

title

Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy (English)

1 reference

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14 January 2020

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5

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14 January 2020

author name string

Zhong Wang

1

1 reference

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14 January 2020

Kevin S Smith

2

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14 January 2020

Mark Murphy

3

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14 January 2020

Obdulio Piloto

4

1 reference

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14 January 2020

Michael L Cleary

6

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14 January 2020

language of work or name

English

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publication date

17 September 2008

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14 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18806775 AND SRC:MED&resulttype=core&format=json

14 January 2020

volume

455

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14 January 2020

issue

7217

1 reference

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14 January 2020

page(s)

1205-1209

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Lithium therapy improves neurological function and hippocampal dendritic arborization in a spinocerebellar ataxia type 1 mouse model

14 January 2020

cites work

1 reference

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p27kip1: a target for tumor therapies?

22 September 2017

1 reference

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Glycogen synthase kinase-3 phosphorylates and regulates the stability of p27kip1 protein

22 September 2017

1 reference

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GSK3 at the edge: regulation of developmental specification and cell polarization

22 September 2017

1 reference

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Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia.

22 September 2017

1 reference

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Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

22 September 2017

1 reference

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Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation

22 September 2017

1 reference

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The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis

22 September 2017

1 reference

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The MLL fusion gene, MLL-AF4, regulates cyclin-dependent kinase inhibitor CDKN1B (p27kip1) expression

22 September 2017

1 reference

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Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors

22 September 2017

1 reference

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MLL: a histone methyltransferase disrupted in leukemia

22 September 2017

1 reference

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Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084721

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

22 September 2017

1 reference

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GSK-3: tricks of the trade for a multi-tasking kinase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084721

The role of glycogen synthase kinase-3 in insulin resistance and type 2 diabetes

22 September 2017

1 reference

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The Wnt signaling pathway in bipolar disorder

22 September 2017

1 reference

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Transformation of bone marrow B-cell progenitors by E2a-Hlf requires coexpression of Bcl-2.

22 September 2017

1 reference

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22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084721

Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084721

22 September 2017

The renaissance of GSK3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084721

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084721

Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084721

Mll rearrangements in haematological malignancies: lessons from clinical and biological studies

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084721

The oncogenic activation of beta-catenin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084721

Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084721

Signal transduction through beta-catenin and specification of cell fate during embryogenesis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084721

The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084721

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084721

Regulation of myeloma cell growth through Akt/Gsk3/forkhead signaling pathway

22 September 2017

1 reference

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Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084721

Glycogen synthase kinase 3 phosphorylates Jun family members in vitro and negatively regulates their transactivating potential in intact cells

17 June 2018

1 reference

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AKT signaling in normal and malignant cells

17 June 2018

1 reference

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Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084721

Wnt signaling controls the phosphorylation status of beta-catenin.

20 August 2018

1 reference

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CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity

20 August 2018

1 reference

Wnt signaling function in Alzheimer's disease

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18806775

12 December 2020

inferred from PubMed ID database lookup

Formation of protein kinase recognition sites by covalent modification of the substrate. Molecular mechanism for the synergistic action of casein kinase II and glycogen synthase kinase 3

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18806775

12 December 2020

inferred from PubMed ID database lookup

Molecular rearrangements on chromosome 11q23 predominate in infant acute lymphoblastic leukemia and are associated with specific biologic variables and poor outcome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18806775

12 December 2020

inferred from PubMed ID database lookup

MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice

1 reference

7 January 2021

Chimeric oncoprotein E2a-Pbx1 induces apoptosis of hematopoietic cells by a p53-independent mechanism that is suppressed by Bcl-2.

1 reference

7 January 2021

Construction and characterization of a conditionally active version of the serine/threonine kinase Akt.

1 reference

7 January 2021

MLL-AFX requires the transcriptional effector domains of AFX to transform myeloid progenitors and transdominantly interfere with forkhead protein function

1 reference

7 January 2021

Cre-lox-regulated conditional RNA interference from transgenes

1 reference

7 January 2021

Identifiers

DOI

10.1038/NATURE07284

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18806775 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

14 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18806775 AND SRC:MED&resulttype=core&format=json

14 January 2020

PubMed publication ID

18806775

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18806775 AND SRC:MED&resulttype=core&format=json