Deletions of CDKN2C in multiple myeloma: biological and clinical implications (Q39933622)

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15 January 2020

title

Deletions of CDKN2C in multiple myeloma: biological and clinical implications (English)

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15 January 2020

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Matthew Jenner

3

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Gian Paolo Dagrada

5

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Gareth J. Morgan

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author name string

Paola E Leone

1

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15 January 2020

Laura Chiecchio

4

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Rebecca K M Protheroe

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David C Johnson

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15 January 2020

Nicholas J Dickens

8

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15 January 2020

Jose Luis Brito

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David Gonzalez

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Fiona M Ross

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Selina Chen-Kiang

13

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Faith E Davies

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Monica Else

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language of work or name

English

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publication date

1 October 2008

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15 January 2020

published in

Clinical Cancer Research

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15 January 2020

volume

14

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15 January 2020

issue

19

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15 January 2020

page(s)

6033-6041

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Paradoxical expression of INK4c in proliferative multiple myeloma tumors: bi-allelic deletion vs increased expression

15 January 2020

cites work

1 reference

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The molecular classification of multiple myeloma

22 September 2017

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A robust algorithm for copy number detection using high-density oligonucleotide single nucleotide polymorphism genotyping arrays

22 September 2017

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A survey of homozygous deletions in human cancer genomes

22 September 2017

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Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma

22 September 2017

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dChipSNP: significance curve and clustering of SNP-array-based loss-of-heterozygosity data

22 September 2017

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Silencing of the p18INK4c gene by promoter hypermethylation in Reed-Sternberg cells in Hodgkin lymphomas

22 September 2017

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Insights into the multistep transformation of MGUS to myeloma using microarray expression analysis

22 September 2017

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Haploinsufficiency of p18(INK4c) sensitizes mice to carcinogen-induced tumorigenesis

22 September 2017

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Frequent inactivation of the cyclin-dependent kinase inhibitor p18 by homozygous deletion in multiple myeloma cell lines: ectopic p18 expression inhibits growth and induces apoptosis

22 September 2017

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Accommodating haploinsufficient tumor suppressor genes in Knudson's model

22 September 2017

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Mutually exclusive cyclin-dependent kinase 4/cyclin D1 and cyclin-dependent kinase 6/cyclin D2 pairing inactivates retinoblastoma protein and promotes cell cycle dysregulation in multiple myeloma

22 September 2017

1 reference

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Molecular cytogenetic abnormalities in multiple myeloma and plasma cell leukemia measured using comparative genomic hybridization

15 June 2018

1 reference

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Prognostic and biologic significance of chromosomal imbalances assessed by comparative genomic hybridization in multiple myeloma

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2581792

Inactivation of the E3/LAPTm5 gene by chromosomal rearrangement and DNA methylation in human multiple myeloma

20 August 2018

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Value of comparative genomic hybridization and fluorescence in situ hybridization for molecular diagnostics in multiple myeloma

20 August 2018

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High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients

20 August 2018

1 reference

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Chromosome abnormalities clustering and its implications for pathogenesis and prognosis in myeloma

2 December 2018

1 reference

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Delineation of distinct subgroups of multiple myeloma and a model for clonal evolution based on interphase cytogenetics

2 December 2018

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12 December 2020

Analysis of p73 and p53 gene deletions in multiple myeloma

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12 December 2020

Ploidy, as detected by fluorescence in situ hybridization, defines different subgroups in multiple myeloma

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12 December 2020

A pooled analysis of karyotypic patterns, breakpoints and imbalances in 783 cytogenetically abnormal multiple myelomas reveals frequently involved chromosome segments as well as significant age- and sex-related differences

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12 December 2020

Characterization of nonrandom chromosomal gains and losses in multiple myeloma by comparative genomic hybridization

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12 December 2020

Analysis of the p16INK4A, p15INK4B and p18INK4C genes in multiple myeloma

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12 December 2020

Chromosome 1 abnormalities in multiple myeloma

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12 December 2020

Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma

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12 December 2020

The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma

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12 December 2020

Deletion of chromosome 13 detected by conventional cytogenetics is a critical prognostic factor in myeloma

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12 December 2020

Age has a profound effect on the incidence and significance of chromosome abnormalities in myeloma

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12 December 2020

Induction of cell cycle arrest and B cell terminal differentiation by CDK inhibitor p18(INK4c) and IL-6

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12 December 2020

High incidence of trisomies 1q, 9q, and 11q in multiple myeloma: results from a comprehensive molecular cytogenetic analysis

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12 December 2020

10.1158/1078-0432.CCR-08-0347

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18829482 AND SRC:MED&resulttype=core&format=json

15 January 2020

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15 January 2020

PubMed publication ID

18829482

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