Phospholipase C delta 1 is a novel 3p22.3 tumor suppressor involved in cytoskeleton organization, with its epigenetic silencing correlated with high-stage gastric cancer. (Q39850176)

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English	Phospholipase C delta 1 is a novel 3p22.3 tumor suppressor involved in cytoskeleton organization, with its epigenetic silencing correlated with high-stage gastric cancer.	scientific article

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28 January 2020

Phospholipase C delta 1 is a novel 3p22.3 tumor suppressor involved in cytoskeleton organization, with its epigenetic silencing correlated with high-stage gastric cancer (English)

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28 January 2020

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X-T Hu

1

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F-B Zhang

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Y-C Fan

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X-S Shu

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A H Y Wong

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W Zhou

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Q-L Shi

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H-M Tang

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C He

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18 May 2009

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28 January 2020

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28 January 2020

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28 January 2020

2466-2475

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28 January 2020

Proteins of the ADF/cofilin family: essential regulators of actin dynamics

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Actin depolymerizing factor (ADF/cofilin) enhances the rate of filament turnover: implication in actin-based motility

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Signalling through phospholipase C interferes with clathrin-mediated endocytosis

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

DLC-1: a Rho GTPase-activating protein and tumour suppressor

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Crystal structure of a mammalian phosphoinositide-specific phospholipase C delta

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Characterization of a novel tumor-suppressor gene PLC delta 1 at 3p22 in esophageal squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Gastric carcinoma

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Structure, regulation, and function of phospholipase C isozymes

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Evaluation of the 3p21.3 tumour-suppressor gene cluster

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Matrix metalloproteinase-7 expression in gastric carcinoma

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Actin-depolymerizing factor and cofilin-1 play overlapping roles in promoting rapid F-actin depolymerization in mammalian nonmuscle cells

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Phospholipase C delta-type consists of three isozymes: bovine PLCdelta2 is a homologue of human/mouse PLCdelta4.

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Phosphoinositide signaling plays a key role in cytokinesis

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

A PLCdelta1-binding protein, p122RhoGAP, is localized in focal adhesions

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Increased expression of matrix metalloproteinase-7 in invasive early gastric cancer

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Prognostic significance of matrix metalloproteinase-7 (MMP-7) expression at the invasive front in gastric carcinoma.

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Analysis of the gene-expression profile regarding the progression of human gastric carcinoma

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Frequent epigenetic inactivation of the RASSF1A tumor suppressor gene in Hodgkin's lymphoma

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

A novel phospholipase C, PLC(eta)2, is a neuron-specific isozyme

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Rho GTPases control polarity, protrusion, and adhesion during cell movement

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Cytogenetic and molecular aspects of gastric cancer: clinical implications

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Estimates of the worldwide incidence of eighteen major cancers in 1985.

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

The candidate tumor suppressor gene BLU, located at the commonly deleted region 3p21.3, is an E2F-regulated, stress-responsive gene and inactivated by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma.

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

The tumor suppressor gene DLEC1 is frequently silenced by DNA methylation in hepatocellular carcinoma and induces G1 arrest in cell cycle.

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Regulation of phosphoinositide-specific phospholipase C

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Transduction of soluble Flt-1 gene to peritoneal mesothelial cells can effectively suppress peritoneal metastasis of gastric cancer

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Supervised membrane swimming: small G-protein lifeguards regulate PIPK signalling and monitor intracellular PtdIns(4,5)P2 pools.

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Morphological changes and detachment of adherent cells induced by p122, a GTPase-activating protein for Rho.

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Relation of matrilysin messenger RNA expression with invasive activity in human gastric cancer

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

WNT5A exhibits tumor-suppressive activity through antagonizing the Wnt/beta-catenin signaling, and is frequently methylated in colorectal cancer.

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

21 January 2018

A dual functional signal mediator showing RhoGAP and phospholipase C-delta stimulating activities

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

31 March 2020

Diversity of gastric carcinogenesis

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

31 March 2020

Postoperative outcome and sites of recurrence in patients following curative resection of gastric cancer

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

31 March 2020

Expression of matrilysin in vascular endothelial cells adjacent to matrilysin-producing tumors

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

31 March 2020

Local cytokines induce differential expression of matrix metalloproteinases but not their tissue inhibitors in human endometrial fibroblasts

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

31 March 2020

Role of MMP-7 in the formation of peritoneal dissemination in gastric cancer

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.92

31 March 2020

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