The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon (Q39844672)

15 September 2017

title

The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon (English)

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15 September 2017

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Chen Wang

1

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15 September 2017

Taoyong Chen

2

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15 September 2017

Jia Zhang

3

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15 September 2017

Mingjin Yang

4

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15 September 2017

Nan Li

5

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15 September 2017

Xiongfei Xu

6

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15 September 2017

Xuetao Cao

7

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15 September 2017

language of work or name

English

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publication date

31 May 2009

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15 September 2017

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15 September 2017

volume

10

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15 September 2017

issue

7

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15 September 2017

page(s)

744-752

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The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

15 September 2017

cites work

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12 December 2020

Lipopolysaccharide-mediated interferon regulatory factor activation involves TBK1-IKKepsilon-dependent Lys(63)-linked polyubiquitination and phosphorylation of TANK/I-TRAF.

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12 December 2020

VISA is an adapter protein required for virus-triggered IFN-beta signaling

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12 December 2020

The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways

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12 December 2020

Lysosome-associated small Rab GTPase Rab7b negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4

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12 December 2020

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

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12 December 2020

The tumor suppressor cylindromatosis (CYLD) acts as a negative regulator for toll-like receptor 2 signaling via negative cross-talk with TRAF6 AND TRAF7.

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12 December 2020

Impact of macrophage and dendritic cell subset elimination on antiviral immunity, viral clearance and production of type 1 interferon

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12 December 2020

FLRF, a novel evolutionarily conserved RING finger gene, is differentially expressed in mouse fetal and adult hematopoietic stem cells and progenitors

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12 December 2020

Ubiquitin signalling in the NF-kappaB pathway

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12 December 2020

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

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12 December 2020

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

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12 December 2020

Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6

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12 December 2020

An RBCC protein implicated in maintenance of steady-state neuregulin receptor levels

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12 December 2020

TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway

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12 December 2020

NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase

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12 December 2020

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

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12 December 2020

Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction

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12 December 2020

Loss of Nrdp1 enhances ErbB2/ErbB3-dependent breast tumor cell growth

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12 December 2020

Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1.

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12 December 2020

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

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12 December 2020

Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis

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12 December 2020

The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20

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12 December 2020

Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20.

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12 December 2020

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

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12 December 2020

Immunity by ubiquitylation: a reversible process of modification

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12 December 2020

The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1

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12 December 2020

Regulation of IkappaB kinase-related kinases and antiviral responses by tumor suppressor CYLD.

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12 December 2020

Neuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1

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12 December 2020

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

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12 December 2020

Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4

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12 December 2020

Unresponsiveness of MyD88-deficient mice to endotoxin

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12 December 2020

Negative regulation of toll-like receptor-mediated immune responses

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12 December 2020

Toll-like receptor signalling

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12 December 2020

TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity

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12 December 2020

Toll-like receptor control of the adaptive immune responses

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12 December 2020

Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3

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12 December 2020

Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

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12 December 2020

E3 ubiquitin ligase Cblb regulates the acute inflammatory response underlying lung injury

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12 December 2020

JNK2 and IKKbeta are required for activating the innate response to viral infection

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12 December 2020

PDLIM2-mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit

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12 December 2020

IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts

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12 December 2020

DUBA: a deubiquitinase that regulates type I interferon production

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12 December 2020

Deubiquitylation and regulation of the immune response

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12 December 2020

Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

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12 December 2020

Identifiers

DOI

10.1038/NI.1742

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Dimensions Publication ID

15 September 2017

1041015763

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