ALK5 inhibition blocks TGFß-induced CCN2 expression in gingival fibroblasts (Q39830423)

15 September 2017

title

ALK5 inhibition blocks TGFß-induced CCN2 expression in gingival fibroblasts (English)

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15 September 2017

2

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15 September 2017

K Thompson

1

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15 September 2017

A Leask

series ordinal

3

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15 September 2017

language of work or name

English

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publication date

5 October 2010

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Journal of Dental Research

15 September 2017

published in

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15 September 2017

volume

89

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15 September 2017

issue

12

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15 September 2017

page(s)

1450-1454

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Transforming growth factor-beta1 (TGFbeta1) stimulates connective tissue growth factor (CCN2/CTGF) expression in human gingival fibroblasts through a RhoA-independent, Rac1/Cdc42-dependent mechanism: statins with forskolin block TGFbeta1-induced CCN

15 September 2017

cites work

1 reference

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Tissue-specific mechanisms for CCN2/CTGF persistence in fibrotic gingiva: interactions between cAMP and MAPK signaling pathways, and prostaglandin E2-EP3 receptor mediated activation of the c-JUN N-terminal kinase

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Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy?

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Connective tissue growth factor is secreted through the Golgi and is degraded in the endosome

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CTGF expression in mesangial cells: involvement of SMADs, MAP kinase, and PKC.

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Human gingival tissues in culture synthesize three metalloproteinases and a metalloproteinase inhibitor

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CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling

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Epithelial and connective tissue cell CTGF/CCN2 expression in gingival fibrosis.

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CCN2 is necessary for the function of mouse embryonic fibroblasts.

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Ethanol-mediated expression of connective tissue growth factor (CCN2) in mouse pancreatic stellate cells

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Domain-specific CCN3 antibodies as unique tools for structural and functional studies

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Transcriptional profiling of the scleroderma fibroblast reveals a potential role for connective tissue growth factor (CTGF) in pathological fibrosis

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TGF-beta signaling and the fibrotic response

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All in the CCN family: essential matricellular signaling modulators emerge from the bunker

21 January 2018

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The control of ccn2 (ctgf) gene expression in normal and scleroderma fibroblasts

21 January 2018

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Connective tissue growth factor gene regulation. Requirements for its induction by transforming growth factor-beta 2 in fibroblasts

21 January 2018

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Regulation of CCN2 mRNA expression and promoter activity in activated hepatic stellate cells

21 January 2018

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Connective tissue growth factor (CTGF, CCN2) gene regulation: a potent clinical bio-marker of fibroproliferative disease?

21 January 2018

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Focal adhesion kinase/Src suppresses early chondrogenesis: central role of CCN2.

21 January 2018

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Expression of connective tissue growth factor in experimental rat and human liver fibrosis

21 January 2018

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CCN2 is necessary for adhesive responses to transforming growth factor-beta1 in embryonic fibroblasts

21 January 2018

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Connective tissue growth factor in drug-induced gingival overgrowth

21 January 2018

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The induction of CCN2 by TGFbeta1 involves Ets-1.

21 January 2018

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9-Cis-retinoic acid exhibits antifibrotic activity via the induction of cyclooxygenase-2 expression and prostaglandin E2 production in scleroderma fibroblasts

21 January 2018

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SB-431542 inhibition of scar formation after filtration surgery and its potential mechanism

21 January 2018

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21 January 2018

Identifiers

DOI

10.1177/0022034510379020

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15 September 2017

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