NFAT signalling is a novel target of oncogenic BRAF in metastatic melanoma. (Q39805013)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19724275 AND SRC:MED&resulttype=core&format=json

6 February 2020

title

NFAT signalling is a novel target of oncogenic BRAF in metastatic melanoma (English)

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6 February 2020

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2

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6 February 2020

Nick J Reynolds

series ordinal

3

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6 February 2020

author name string

R J Flockhart

series ordinal

1

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6 February 2020

P E Lovat

series ordinal

4

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6 February 2020

language of work or name

English

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publication date

1 September 2009

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British Journal of Cancer

6 February 2020

published in

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6 February 2020

volume

101

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6 February 2020

issue

8

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6 February 2020

page(s)

1448-1455

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Braf(V600E) cooperates with Pten loss to induce metastatic melanoma

6 February 2020

cites work

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NFAT regulates induction of COX-2 and apoptosis of keratinocytes in response to ultraviolet radiation exposure.

22 September 2017

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Therapeutic strategies for inhibiting oncogenic BRAF signaling

22 September 2017

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22 September 2017

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Elevated CRAF as a potential mechanism of acquired resistance to BRAF inhibition in melanoma

22 September 2017

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The calcineurin/NFAT signaling pathway: a novel therapeutic target in leukemia and solid tumors

22 September 2017

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Therapeutic potential of VIVIT, a selective peptide inhibitor of nuclear factor of activated T cells, in cardiovascular disorders

22 September 2017

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Hyperactive Ras in developmental disorders and cancer

22 September 2017

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An emerging role for Ca2 /calcineurin/NFAT signaling in cancerogenesis

22 September 2017

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New insight into BRAF mutations in cancer

22 September 2017

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BRAF mutations in papillary thyroid carcinoma

22 September 2017

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Temozolomide in combination with celecoxib in patients with advanced melanoma. A phase II study of the Hellenic Cooperative Oncology Group

22 September 2017

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Targeting mitogen-activated protein kinase/extracellular signal-regulated kinase kinase in the mutant (V600E) B-Raf signaling cascade effectively inhibits melanoma lung metastases

22 September 2017

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BRAFE600-associated senescence-like cell cycle arrest of human naevi

22 September 2017

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Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors

22 September 2017

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Direct and indirect interactions between calcineurin-NFAT and MEK1-extracellular signal-regulated kinase 1/2 signaling pathways regulate cardiac gene expression and cellular growth

22 September 2017

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B-Raf contributes to sustained extracellular signal-regulated kinase activation associated with interleukin-2 production stimulated through the T cell receptor.

22 September 2017

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B-RAF is a therapeutic target in melanoma

22 September 2017

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Nuclear factor of activated T cells balances angiogenesis activation and inhibition.

22 September 2017

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Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

22 September 2017

1 reference

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Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy

22 September 2017

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Transcriptional regulation by calcium, calcineurin, and NFAT

22 September 2017

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High frequency of BRAF mutations in nevi

22 September 2017

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The role of NFAT transcription factors in integrin-mediated carcinoma invasion

22 September 2017

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Mutations of the BRAF gene in human cancer

22 September 2017

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Partners in transcription: NFAT and AP-1.

22 September 2017

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Gene expression elicited by NFAT in the presence or absence of cooperative recruitment of Fos and Jun.

22 September 2017

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FK506, an immunosuppressant targeting calcineurin function

22 September 2017

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The mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor AZD6244 (ARRY-142886) induces growth arrest in melanoma cells and tumor regression when combined with docetaxel

22 September 2017

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Cyclooxygenase-2 (COX-2): first immunohistochemical marker distinguishing early cutaneous melanomas from benign melanocytic skin tumours.

20 August 2018

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ISA(TX)247: a novel calcineurin inhibitor.

20 August 2018

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Ras regulates NFAT3 activity in cardiac myocytes

20 August 2018

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An Essential Role of the Nuclear Factor of Activated T Cells in the Regulation of the Expression of the Cyclooxygenase-2 Gene in Human T Lymphocytes

20 August 2018

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Crossref

https://api.crossref.org/works/10.1038/SJ.BJC.6605277

Cancer in immune-suppressed organ transplant recipients: aetiology and evolution

21 January 2018

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12 December 2020

Immunosuppressive factors: role in cancer development and progression

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12 December 2020

Expression of cyclooxygenase-2 in benign naevi and during human cutaneous melanoma progression

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12 December 2020

In vivo evaluation of the novel calcineurin inhibitor ISATX247 in non-human primates

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12 December 2020

Identifiers

DOI

10.1038/SJ.BJC.6605277

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19724275 AND SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19724275 AND SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

19724275

1 reference