Chemoprotection of human hematopoietic stem cells by simultaneous lentiviral overexpression of multidrug resistance 1 and O(6)-methylguanine-DNA methyltransferase(P140K). (Q39782231)

From Wikidata

Jump to navigation Jump to search

scientific article published on 29 October 2009

Language	Label	Description	Also known as
English	Chemoprotection of human hematopoietic stem cells by simultaneous lentiviral overexpression of multidrug resistance 1 and O(6)-methylguanine-DNA methyltransferase(P140K).	scientific article published on 29 October 2009

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Chemoprotection of human hematopoietic stem cells by simultaneous lentiviral overexpression of multidrug resistance 1 and O(6)-methylguanine-DNA methyltransferase(P140K). (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

1 reference

based on heuristic

inferred from title

multiple drug resistance

1 reference

based on heuristic

inferred from title

author name string

P Maier

1

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

I Spier

2

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

S Laufs

3

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

M R Veldwijk

4

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

S Fruehauf

5

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

F Wenz

6

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

W J Zeller

7

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

publication date

29 October 2009

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

17

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

389-399

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Frequency analysis of multidrug resistance-1 gene transfer into human primitive hematopoietic progenitor cells using the cobblestone area-forming cell assay and detection of vector-mediated P-glycoprotein expression by rhodamine-123.

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Multidrug resistance 1 gene transfer can confer chemoprotection to human peripheral blood progenitor cells engrafted in immunodeficient mice

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Gene therapy to protect haematopoietic cells from cytotoxic cancer drugs

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Gene therapy for breast cancer. --Review of clinical gene therapy trials for breast cancer and MDR1 gene therapy trial in Cancer Institute Hospital

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

DNA cross-linking and monoadduct repair in nitrosourea-treated human tumour cells

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Ubiquitination-dependent proteolysis of O6-methylguanine-DNA methyltransferase in human and murine tumor cells following inactivation with O6-benzylguanine or 1,3-bis(2-chloroethyl)-1-nitrosourea

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Protection of hematopoietic cells from O(6)-alkylation damage by O(6)-methylguanine DNA methyltransferase gene transfer: studies with different O(6)-alkylating agents and retroviral backbones

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Lentivirus-mediated expression of mutant MGMTP140K protects human CD34 cells against the combined toxicity of O6-benzylguanine and 1,3-bis(2-chloroethyl)-nitrosourea or temozolomide

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Lentiviral transduction of P140K MGMT into human CD34( ) hematopoietic progenitors at low multiplicity of infection confers significant resistance to BG/BCNU and allows selection in vitro

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

In vivo selection of human hematopoietic cells in a xenograft model using combined pharmacologic and genetic manipulations

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Polyclonal chemoprotection against temozolomide in a large-animal model of drug resistance gene therapy

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

A novel dual function retrovirus expressing multidrug resistance 1 and O6-alkylguanine-DNA-alkyltransferase for engineering resistance of haemopoietic progenitor cells to multiple chemotherapeutic agents

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Improvement of combination chemotherapy tolerance by introduction of polycistronic retroviral vector drug resistance genes MGMT and MDR1 into human umbilical cord blood CD34 cells

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Dual agent chemoprotection by retroviral co-expression of either MDR1 or MRP1 with the P140K mutant of O6-methylguanine-DNA-methyl transferase

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Lentiviral gene transfer into peripheral blood-derived CD34 NOD/SCID-repopulating cells

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

High-level transduction and gene expression in hematopoietic repopulating cells using a human immunodeficiency [correction of imunodeficiency] virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoter

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

IRES-dependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Improved co-expression of multiple genes in vectors containing internal ribosome entry sites (IRESes) from human genes.

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

A new method to evaluate in vitro myelotoxicity of antitumour agents in the first steps of drug development.

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Chemotherapy for non-small cell lung cancer: the experience of the Lung Cancer Cooperative Group of the European Organization for Research and Treatment of Cancer

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Phase I study of temozolomide plus paclitaxel in patients with advanced malignant melanoma and associated in vitro investigations.

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

MGMT gene silencing and benefit from temozolomide in glioblastoma

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Insertion of retroviral vectors in NOD/SCID repopulating human peripheral blood progenitor cells occurs preferentially in the vicinity of transcription start regions and in introns

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Lentiviral vector integration sites in human NOD/SCID repopulating cells

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Clinical application of lentiviral vectors - concepts and practice

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Gene therapy fulfilling its promise

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Lentiviral vector gene transfer is limited by the proteasome at postentry steps in various types of stem cells

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Improved post-transcriptional processing of an MDR1 retrovirus elevates expression of multidrug resistance in primary human hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

21 January 2018

Biochemistry of multidrug resistance mediated by the multidrug transporter

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

7 January 2021

based on heuristic

inferred from DOI database lookup

Phase I trial of retroviral-mediated transfer of the human MDR1 gene as marrow chemoprotection in patients undergoing high-dose chemotherapy and autologous stem-cell transplantation.

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

7 January 2021

based on heuristic

inferred from DOI database lookup

O6-benzylguanine in humans: metabolic, pharmacokinetic, and pharmacodynamic findings

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

7 January 2021

based on heuristic

inferred from DOI database lookup

Phase I trial of carmustine plus O6-benzylguanine for patients with recurrent or progressive malignant glioma

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

7 January 2021

based on heuristic

inferred from DOI database lookup

A third-generation lentivirus vector with a conditional packaging system

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

7 January 2021

based on heuristic

inferred from DOI database lookup

CD34 selection for purging in multiple myeloma and analysis of CD34 B cell precursors

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

7 January 2021

based on heuristic

inferred from DOI database lookup

Salvage chemotherapy with paclitaxel for recurrent primary brain tumors

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

7 January 2021

based on heuristic

inferred from DOI database lookup

Equal potency of gammaretroviral and lentiviral SIN vectors for expression of O6-methylguanine-DNA methyltransferase in hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

7 January 2021

based on heuristic

inferred from DOI database lookup

No evidence of clonal dominance in primates up to 4 years following transplantation of multidrug resistance 1 retrovirally transduced long-term repopulating cells

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

7 January 2021

based on heuristic

inferred from DOI database lookup

MDR1 gene transfer using a lentiviral SIN vector confers radioprotection to human CD34 hematopoietic progenitor cells

1 reference

https://api.crossref.org/works/10.1038/GT.2009.133

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/GT.2009.133

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q39782231&oldid=2203171754"