Inhibition of Akt signaling by the lignan matairesinol sensitizes prostate cancer cells to TRAIL-induced apoptosis (Q39771163)

14 September 2017

title

Inhibition of Akt signaling by the lignan matairesinol sensitizes prostate cancer cells to TRAIL-induced apoptosis (English)

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14 September 2017

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ChEBI release 2020-05-28

E Torvaldson

4

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Emilia Peuhu

object named as

E Peuhu

1

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Adolfo Rivero-Müller

object named as

A Rivero-Müller

2

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author name string

H Stykki

3

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14 September 2017

T Holmbom

5

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P Eklund

6

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M Unkila

7

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R Sjöholm

8

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J E Eriksson

9

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14 September 2017

language of work or name

English

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publication date

23 November 2009

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volume

29

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issue

6

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page(s)

898-908

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cites work

Lignans and human health

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https://api.crossref.org/works/10.1038/ONC.2009.386

Akt and 14-3-3 control a PACS-2 homeostatic switch that integrates membrane traffic with TRAIL-induced apoptosis

21 January 2018

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Origin of lignans in mammals and identification of a precursor from plants

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APO2 ligand/tumor necrosis factor-related apoptosis-inducing ligand in prostate cancer therapy

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Enterolactone inhibits insulin-like growth factor-1 receptor signaling in human prostatic carcinoma PC-3 cells

21 January 2018

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https://api.crossref.org/works/10.1038/ONC.2009.386

Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer

21 January 2018

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https://api.crossref.org/works/10.1038/ONC.2009.386

Cell death: critical control points

21 January 2018

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Signaling through death receptors in cancer therapy

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Naturally occurring lignans efficiently induce apoptosis in colorectal tumor cells

21 January 2018

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Androgens repress Bcl-2 expression via activation of the retinoblastoma (RB) protein in prostate cancer cells

21 January 2018

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Annual report to the nation on the status of cancer, 1975-2005, featuring trends in lung cancer, tobacco use, and tobacco control

21 January 2018

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Deficient tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor transport to the cell surface in human colon cancer cells selected for resistance to TRAIL-induced apoptosis.

21 January 2018

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Pretreatment of acetylsalicylic acid promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by down-regulating BCL-2 gene expression

21 January 2018

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The promise of TRAIL--potential and risks of a novel anticancer therapy

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Dietary supplementation with secoisolariciresinol diglycoside (SDG) reduces experimental metastasis of melanoma cells in mice.

21 January 2018

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TRAIL receptor signalling and modulation: Are we on the right TRAIL?

21 January 2018

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Enterolactone restricts the proliferation of the LNCaP human prostate cancer cell line in vitro

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Role of mammalian lignans in the prevention and treatment of prostate cancer.

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FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

21 January 2018

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Elevated AKT activity protects the prostate cancer cell line LNCaP from TRAIL-induced apoptosis

21 January 2018

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Lethal effect of the anti-Fas antibody in mice

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An Antagonist Decoy Receptor and a Death Domain-Containing Receptor for TRAIL

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The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis.

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Sensitization of prostate carcinoma cells to Apo2L/TRAIL by a Bcl-2 family protein inhibitor

21 January 2018

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Androgen regulates apoptosis induced by TNFR family ligands via multiple signaling pathways in LNCaP.

21 January 2018

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TRAIL-DISC formation is androgen-dependent in the human prostatic carcinoma cell line LNCaP.

21 January 2018

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Dietary lariciresinol attenuates mammary tumor growth and reduces blood vessel density in human MCF-7 breast cancer xenografts and carcinogen-induced mammary tumors in rats.

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TRAIL: a multifunctional cytokine

21 January 2018

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Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors

21 January 2018

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The interplay between the Bcl-2 family and death receptor-mediated apoptosis

21 January 2018

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Pro-survival function of Akt/protein kinase B in prostate cancer cells. Relationship with TRAIL resistance

21 January 2018

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Characterization of (-)-matairesinol as a potent inhibitor of casein kinase I in vitro

21 January 2018

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Inhibition of human aromatase by mammalian lignans and isoflavonoid phytoestrogens

21 January 2018

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Antioxidant activity of the flaxseed lignan secoisolariciresinol diglycoside and its mammalian lignan metabolites enterodiol and enterolactone

31 March 2020

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Antitumorigenic effect of a mammalian lignan precursor from flaxseed

31 March 2020

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https://api.crossref.org/works/10.1038/ONC.2009.386

Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.386

31 March 2020

Identifiers

DOI

10.1038/ONC.2009.386

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14 September 2017

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