A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion (Q39769621)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27032374 AND SRC:MED&resulttype=core&format=json

31 March 2020

title

A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion (English)

1 reference

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intrahepatic cholangiocarcinoma

31 March 2020

main subject

cholangiocarcinoma

0 references

1 reference

Corrigendum: A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion

inferred from title

corrigendum / erratum

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author

Hayato Nakagawa

3

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31 March 2020

Rei Noguchi

7

1 reference

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31 March 2020

17

Kazuhiko Koike

1 reference

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31 March 2020

15

Noriyoshi Fukushima

1 reference

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31 March 2020

author name string

Tsuneo Ikenoue

1

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31 March 2020

Yumi Terakado

2

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31 March 2020

Yohko Hikiba

4

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31 March 2020

Tomoaki Fujii

5

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31 March 2020

Daisuke Matsubara

6

1 reference

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31 March 2020

Chi Zhu

8

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31 March 2020

Keisuke Yamamoto

9

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31 March 2020

Yotaro Kudo

10

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31 March 2020

Yoshinari Asaoka

11

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31 March 2020

Kiyoshi Yamaguchi

12

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31 March 2020

Hideaki Ijichi

13

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31 March 2020

Keisuke Tateishi

14

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31 March 2020

Shin Maeda

16

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31 March 2020

Yoichi Furukawa

18

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31 March 2020

language of work or name

English

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publication date

1 April 2016

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31 March 2020

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31 March 2020

volume

6

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31 March 2020

page(s)

23899

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Multigene mutational profiling of cholangiocarcinomas identifies actionable molecular subgroups

31 March 2020

cites work

1 reference

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New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing

22 September 2017

1 reference

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Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

22 September 2017

1 reference

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Pathogenesis, diagnosis, and management of cholangiocarcinoma

22 September 2017

1 reference

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Cholangiocarcinomas can originate from hepatocytes in mice

22 September 2017

1 reference

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Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma

22 September 2017

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Histological diversity in cholangiocellular carcinoma reflects the different cholangiocyte phenotypes.

22 September 2017

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The role of cancer-associated myofibroblasts in intrahepatic cholangiocarcinoma

22 September 2017

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CpG-island methylation study of liver fluke-related cholangiocarcinoma.

22 September 2017

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The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis.

22 September 2017

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MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3.

22 September 2017

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A CK19(CreERT) knockin mouse line allows for conditional DNA recombination in epithelial cells in multiple endodermal organs

22 September 2017

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A global double-fluorescent Cre reporter mouse

22 September 2017

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Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression

22 September 2017

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Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer

22 September 2017

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Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice

22 September 2017

1 reference

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Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

22 September 2017

1 reference

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Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas

22 September 2017

1 reference

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Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

22 September 2017

1 reference

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Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma

22 September 2017

1 reference

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Changing international trends in mortality rates for liver, biliary and pancreatic tumours

22 September 2017

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Increasing incidence and mortality of primary intrahepatic cholangiocarcinoma in the United States

22 September 2017

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Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

22 September 2017

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22 September 2017

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Cell lineage tracing reveals a biliary origin of intrahepatic cholangiocarcinoma

15 June 2018

1 reference

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High incidence of ras gene mutation in intrahepatic cholangiocarcinoma

15 June 2018

1 reference

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15 June 2018

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Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity

20 August 2018

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Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers

20 August 2018

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A critical role for notch signaling in the formation of cholangiocellular carcinomas

20 August 2018

1 reference

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PTEN loss and KRAS activation cooperate in murine biliary tract malignancies

20 August 2018

1 reference

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Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes

20 August 2018

1 reference

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KrasG12D and p53 Mutation Cause Primary Intrahepatic Cholangiocarcinoma

20 August 2018

1 reference

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Interleukin-6 contributes to Mcl-1 up-regulation and TRAIL resistance via an Akt-signaling pathway in cholangiocarcinoma cells

20 August 2018

1 reference

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Efficient temporally controlled targeted somatic mutagenesis in hepatocytes of the mouse

20 August 2018

1 reference

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Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

20 August 2018

1 reference

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Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinoma

20 August 2018

1 reference

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Frequency of p16(INK4A) alterations and K-ras mutations in intrahepatic cholangiocarcinoma of the liver

20 August 2018

1 reference

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Ki-ras mutations and p53 protein expressions in intrahepatic cholangiocarcinomas: relation to gross tumor morphology.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817147

RAF/RAS oncogenes and mismatch-repair status

20 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038/SREP23899

T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038/SREP23899

21 January 2018

1 reference

12 December 2020

DNA excision in liver by an albumin-Cre transgene occurs progressively with age

1 reference

12 December 2020

Microsatellite instability and alternative genetic pathway in intrahepatic cholangiocarcinoma

1 reference

12 December 2020

Comparative immunohistochemical profile of hepatocellular carcinoma, cholangiocarcinoma, and metastatic adenocarcinoma

1 reference

12 December 2020

Exome sequencing of liver fluke-associated cholangiocarcinoma

1 reference

12 December 2020

Identifiers

DOI

10.1038/SREP23899

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27032374 AND SRC:MED&resulttype=core&format=json

31 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27032374 AND SRC:MED&resulttype=core&format=json

31 March 2020

PubMed publication ID

27032374

1 reference