CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa (Q39749802)

14 September 2017

CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa (English)

1 reference

14 September 2017

0 references

Wen-Hsuan Wu

1

1 reference

14 September 2017

Yi-Ting Tsai

2

1 reference

14 September 2017

Sally Justus

3

1 reference

14 September 2017

Ting-Ting Lee

4

1 reference

14 September 2017

Lijuan Zhang

5

1 reference

14 September 2017

Chyuan-Sheng Lin

6

1 reference

14 September 2017

Alexander G Bassuk

7

1 reference

14 September 2017

Vinit B Mahajan

8

1 reference

14 September 2017

Stephen H Tsang

9

1 reference

14 September 2017

20 May 2016

1 reference

14 September 2017

1 reference

14 September 2017

24

1 reference

14 September 2017

8

1 reference

14 September 2017

1388-1394

1 reference

Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

Halting progressive neurodegeneration in advanced retinitis pigmentosa

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

Validation of genome-wide association study (GWAS)-identified disease risk alleles with patient-specific stem cell lines

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

Functional validation of a human CAPN5 exome variant by lentiviral transduction into mouse retina

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

Mid-stage intervention achieves similar efficacy as conventional early-stage treatment using gene therapy in a pre-clinical model of retinitis pigmentosa

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

Therapeutic margins in a novel preclinical model of retinitis pigmentosa.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

Multiplex genome engineering using CRISPR/Cas systems

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

shRNA knockdown of guanylate cyclase 2e or cyclic nucleotide gated channel alpha 1 increases photoreceptor survival in a cGMP phosphodiesterase mouse model of retinitis pigmentosa

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

THE GEOTROPIC REACTION OF RODLESS MICE IN LIGHT AND IN DARKNESS

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

Functional rescue of degenerating photoreceptors in mice homozygous for a hypomorphic cGMP phosphodiesterase 6 b allele (Pde6bH620Q).

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

Perspective on genes and mutations causing retinitis pigmentosa

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

Retinal degeneration in mice lacking the gamma subunit of the rod cGMP phosphodiesterase

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

PCR analysis of DNA from 70-year-old sections of rodless retina demonstrates identity with the mouse rd defect

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

Localization of a retroviral element within the rd gene coding for the beta subunit of cGMP phosphodiesterase

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

Retinal photoreceptor dystrophies LI. Edward Jackson Memorial Lecture

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

Mutation spectrum of the gene encoding the beta subunit of rod phosphodiesterase among patients with autosomal recessive retinitis pigmentosa

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

Identification of a nonsense mutation in the rod photoreceptor cGMP phosphodiesterase beta-subunit gene of the rd mouse

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

Mouse Eye Enucleation for Remote High-throughput Phenotyping

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023380

Role for the target enzyme in deactivation of photoreceptor G protein in vivo

15 June 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27203441

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/MT.2016.107

1 reference

14 September 2017

1 reference

14 September 2017

PubMed publication ID

27203441

1 reference