Distribution of AAV8 particles in cell lysates and culture media changes with time and is dependent on the recombinant vector (Q39680091)

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1 April 2020

title

Distribution of AAV8 particles in cell lysates and culture media changes with time and is dependent on the recombinant vector (English)

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1 April 2020

1

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1 April 2020

author name string

Jason E Drury

2

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1 April 2020

Christopher L Morton

3

1 reference

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1 April 2020

Yunyu Spence

4

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1 April 2020

Timothy D Lockey

5

1 reference

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1 April 2020

Amit C Nathwani

6

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1 April 2020

Andrew M Davidoff

7

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1 April 2020

Michael M Meagher

8

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1 April 2020

publication date

30 March 2016

1 reference

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Molecular Therapy. Methods & Clinical Development

1 April 2020

published in

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1 April 2020

volume

3

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1 April 2020

page(s)

16015

1 reference

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Production of Recombinant Adeno-associated Virus Vectors Using Suspension HEK293 Cells and Continuous Harvest of Vector From the Culture Media for GMP FIX and FLT1 Clinical Vector

1 April 2020

cites work

1 reference

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Manufacturing and characterization of a recombinant adeno-associated virus type 8 reference standard material.

14 September 2017

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Current status of haemophilia gene therapy

14 September 2017

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Production of adeno-associated virus (AAV) serotypes by transient transfection of HEK293 cell suspension cultures for gene delivery

14 September 2017

1 reference

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Systemic delivery of shRNA by AAV9 provides highly efficient knockdown of ubiquitously expressed GFP in mouse heart, but not liver

14 September 2017

1 reference

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Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variant

14 September 2017

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The AAV Vector Toolkit: Poised at the Clinical Crossroads

14 September 2017

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Preclinical Dose-Finding Study With a Liver-Tropic, Recombinant AAV-2/8 Vector in the Mouse Model of Galactosialidosis

14 September 2017

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The assembly-activating protein promotes capsid assembly of different adeno-associated virus serotypes

14 September 2017

1 reference

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Good Manufacturing Practice Production of Self-Complementary Serotype 8 Adeno-Associated Viral Vector for a Hemophilia B Clinical Trial

14 September 2017

1 reference

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Reproducible High Yields of Recombinant Adeno-Associated Virus Produced Using Invertebrate Cells in 0.02- to 200-Liter Cultures

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813606

Manufacturing and regulatory strategies for clinical AAV2-hRPE65.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813606

Large-scale adeno-associated viral vector production using a herpesvirus-based system enables manufacturing for clinical studies

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813606

Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813606

Safe and efficient transduction of the liver after peripheral vein infusion of self-complementary AAV vector results in stable therapeutic expression of human FIX in nonhuman primates

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813606

Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813606

Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813606

Adeno-associated virus vectors in clinical trials

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813606

Improving rAAV production and purification: towards the definition of a scaleable process

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813606

Scalable purification of adeno-associated virus serotype 1 (AAV1) and AAV8 vectors, using dual ion-exchange adsorptive membranes.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813606

Scalable recombinant adeno-associated virus production using recombinant herpes simplex virus type 1 coinfection of suspension-adapted mammalian cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813606

Scalable serum-free production of recombinant adeno-associated virus type 2 by transfection of 293 suspension cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813606

Efficient serotype-dependent release of functional vector into the culture medium during adeno-associated virus manufacturing.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813606

Rapid, simple, and versatile manufacturing of recombinant adeno-associated viral vectors at scale.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813606

Adeno-Associated Viral Vectors Found Free in Media

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813606

21 August 2018

Identifiers

DOI

10.1038/MTM.2016.15

1 reference

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release_22bwvpvztbhz3jv5hys4hcg6im

1 April 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/22bwvpvztbhz3jv5hys4hcg6im

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

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1 April 2020

PubMed publication ID

27069949

1 reference

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