Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals. (Q39648228)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12234923 AND SRC:MED&resulttype=core&format=json

13 November 2019

title

Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals (English)

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13 November 2019

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Aristides G Eliopoulos

1

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13 November 2019

author name string

Calin D Dumitru

2

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13 November 2019

Chun-Chi Wang

3

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13 November 2019

Jeonghee Cho

4

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13 November 2019

Philip N Tsichlis

5

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13 November 2019

language of work or name

English

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publication date

1 September 2002

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13 November 2019

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13 November 2019

volume

21

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13 November 2019

issue

18

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13 November 2019

page(s)

4831-4840

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The oncogenic protein kinase Tpl-2/Cot contributes to Epstein-Barr virus-encoded latent infection membrane protein 1-induced NF-kappaB signaling downstream of TRAF2

13 November 2019

cites work

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Mitogen-regulated RSK2-CBP interaction controls their kinase and acetylase activities

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Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice

14 September 2017

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Transcriptional regulation by the phosphorylation-dependent factor CREB

14 September 2017

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Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes

14 September 2017

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Cot kinase induces cyclooxygenase-2 expression in T cells through activation of the nuclear factor of activated T cells

14 September 2017

1 reference

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Tumor necrosis factor-alpha-induced cyclooxygenase-2 expression via sequential activation of ceramide-dependent mitogen-activated protein kinases, and IkappaB kinase 1/2 in human alveolar epithelial cells.

14 September 2017

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TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway

14 September 2017

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MSK1 is required for CREB phosphorylation in response to mitogens in mouse embryonic stem cells

14 September 2017

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Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade

14 September 2017

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Rsk1 mediates a MEK-MAP kinase cell survival signal

14 September 2017

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The nucleosomal response associated with immediate-early gene induction is mediated via alternative MAP kinase cascades: MSK1 as a potential histone H3/HMG-14 kinase

14 September 2017

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Requirement of Rsk-2 for epidermal growth factor-activated phosphorylation of histone H3

14 September 2017

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Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction.

14 September 2017

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The febrile response to lipopolysaccharide is blocked in cyclooxygenase-2(-/-), but not in cyclooxygenase-1(-/-) mice

14 September 2017

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Induction of cyclooxygenase-2 by activated Ha-ras oncogene in Rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway

14 September 2017

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Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

14 September 2017

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Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation

14 September 2017

1 reference

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The Tpl-2 protooncoprotein activates the nuclear factor of activated T cells and induces interleukin 2 expression in T cell lines.

14 September 2017

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Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)

14 September 2017

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Involvement of the Tpl-2/cot oncogene in MMTV tumorigenesis

14 September 2017

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Phosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL6

14 September 2017

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Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation

14 September 2017

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Role of mitogen-activated protein kinase cascades in mediating lipopolysaccharide-stimulated induction of cyclooxygenase-2 and IL-1 beta in RAW264 macrophages

14 September 2017

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Activation of the p38 mitogen-activated protein kinase pathway by Epstein-Barr virus-encoded latent membrane protein 1 coregulates interleukin-6 and interleukin-8 production

25 September 2017

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Transcriptional activation of cyclooxygenase-2 in Wnt-1-transformed mouse mammary epithelial cells

25 September 2017

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25 September 2017

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Pathogenetic mechanisms of septic shock

25 September 2017

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Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation

25 September 2017

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25 September 2017

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Transcriptional activation of the cyclooxygenase-2 gene in endotoxin-treated RAW 264.7 macrophages

25 September 2017

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Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing

15 June 2018

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15 June 2018

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15 June 2018

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Increased cyclooxygenase-2 (cox-2) expression and activity in a murine model of metastatic breast cancer

15 June 2018

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Bacterial infection promotes colon tumorigenesis in Apc(Min/ ) mice

21 August 2018

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12 December 2020

Monocyte response to bacterial toxins, expression of cell surface receptors, and release of anti-inflammatory cytokines during sepsis

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12 December 2020

COX-2 inhibitors for colorectal cancer

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12 December 2020

Tpl-2 induces IL-2 expression in T-cell lines by triggering multiple signaling pathways that activate NFAT and NF-kappaB

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12 December 2020

Phosphorylation of cytosolic phospholipase A2 and the release of arachidonic acid in human neutrophils

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12 December 2020

Lipopolysaccharide modulates cyclooxygenase-2 transcriptionally and posttranscriptionally in human macrophages independently from endogenous IL-1 beta and TNF-alpha

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12 December 2020

Microcomputer-assisted kinetic modeling of mammalian gene expression

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12 December 2020

Identifiers

DOI

10.1093/EMBOJ/CDF478

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12234923 AND SRC:MED&resulttype=core&format=json

13 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12234923 AND SRC:MED&resulttype=core&format=json

13 November 2019

PubMed publication ID

12234923

1 reference