Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha (Q39635625)

13 September 2017

title

Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha (English)

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13 September 2017

Lukasz Magiera

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Matthew Kraman

object named as

Matthew Kraman

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Edward W Roberts

object named as

Edward W Roberts

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David Tuveson

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object named as

David A Tuveson

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13 September 2017

Paul J Bambrough

2

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13 September 2017

James N Arnold

3

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13 September 2017

James O Jones

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13 September 2017

Aarthi Gopinathan

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13 September 2017

Douglas T Fearon

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13 September 2017

language of work or name

English

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publication date

1 November 2010

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13 September 2017

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13 September 2017

volume

330

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13 September 2017

issue

6005

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13 September 2017

page(s)

827-830

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A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma

13 September 2017

cites work

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Immunogenicity of premalignant lesions is the primary cause of general cytotoxic T lymphocyte unresponsiveness

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Tumor progression can occur despite the induction of very high levels of self/tumor antigen-specific CD8 T cells in patients with melanoma

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Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming.

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Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

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T-cell-mediated suppression of anti-tumor immunity. An explanation for progressive growth of an immunogenic tumor

21 January 2018

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Inhibition of tumor growth by elimination of granulocytes

21 January 2018

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Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells.

21 January 2018

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Cancer-related inflammation

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A nonclassical non-Valpha14Jalpha18 CD1d-restricted (type II) NKT cell is sufficient for down-regulation of tumor immunosurveillance

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Intratumor depletion of CD4 cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors

21 January 2018

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Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

21 January 2018

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Cell surface glycoprotein of reactive stromal fibroblasts as a potential antibody target in human epithelial cancers

21 January 2018

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Fibroblast activation protein is expressed by rheumatoid myofibroblast-like synoviocytes

21 January 2018

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Adult stem cells from bone marrow (MSCs) isolated from different strains of inbred mice vary in surface epitopes, rates of proliferation, and differentiation potential

21 January 2018

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Fibroblast activation protein alpha identifies mesenchymal stromal cells from human bone marrow

21 January 2018

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Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice

21 January 2018

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Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

21 January 2018

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IFN-gamma- and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers

21 January 2018

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Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

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Cell intrinsic mechanisms of T-cell inhibition and application to cancer therapy

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21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1195300

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13 September 2017

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