Nerve growth factor receptor TrkA exists as a preformed, yet inactive, dimer in living cells (Q39615370)

13 September 2017

title

Nerve growth factor receptor TrkA exists as a preformed, yet inactive, dimer in living cells (English)

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Neurotrophic receptor tyrosine kinase 1

13 September 2017

main subject

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identical protein binding

GOA release 2020-03-11

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GOA release 2020-03-11

1

Jianying Shen

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21187090

20 November 2024

2

Ichiro N. Maruyama

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21187090

20 November 2024

language of work or name

English

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publication date

25 December 2010

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full work available at URL

13 September 2017

number of pages

5

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based on heuristic

inferred from page(s)

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016/j.febslet.2010.12.031

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2010.12.031

http://onlinelibrary.wiley.com/wol1/doi/10.1016/j.febslet.2010.12.031/fullpdf

20 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2010.12.031

20 November 2024

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13 September 2017

volume

585

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13 September 2017

issue

2

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13 September 2017

page(s)

295-299

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Neurotrophin signal transduction in the nervous system

13 September 2017

cites work

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Molecular investigations on the high-affinity nerve growth factor receptor

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Nerve growth factor mediates signal transduction through trk homodimer receptors

21 January 2018

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New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor

21 January 2018

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Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor

21 January 2018

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Genuine Monovalent Ligands of TrkA Nerve Growth Factor Receptors Reveal a Novel Pharmacological Mechanism of Action

21 January 2018

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Heterodimeric neurotrophins induce phosphorylation of Trk receptors and promote neuronal differentiation in PC12 cells

21 January 2018

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Nerve growth factor signals via preexisting TrkA receptor oligomers

21 January 2018

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Identification of new fluorescent protein fragments for bimolecular fluorescence complementation analysis under physiological conditions

21 January 2018

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All EGF(ErbB) receptors have preformed homo- and heterodimeric structures in living cells.

21 January 2018

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Molecular dissection of TrkA signal transduction pathways mediating differentiation in human neuroblastoma cells

21 January 2018

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Inhibition of receptor-mediated but not fluid-phase endocytosis in polymorphonuclear leukocytes

21 January 2018

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Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation

21 January 2018

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Molecular kinetics of nerve growth factor receptor trafficking and activation

21 January 2018

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Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation

21 January 2018

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A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

21 January 2018

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Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animals

21 January 2018

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Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain

21 January 2018

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Ligand-independent dimer formation of epidermal growth factor receptor (EGFR) is a step separable from ligand-induced EGFR signaling

21 January 2018

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Preformed oligomeric epidermal growth factor receptors undergo an ectodomain structure change during signaling

21 January 2018

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Ligand-induced dimer-tetramer transition during the activation of the cell surface epidermal growth factor receptor-A multidimensional microscopy analysis

21 January 2018

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Investigation of the dimerization of proteins from the epidermal growth factor receptor family by single wavelength fluorescence cross-correlation spectroscopy

21 January 2018

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Ligand-independent growth hormone receptor dimerization occurs in the endoplasmic reticulum and is required for ubiquitin system-dependent endocytosis

21 January 2018

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Model for growth hormone receptor activation based on subunit rotation within a receptor dimer

21 January 2018

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Ligand-induced conformational changes allosterically activate Toll-like receptor 9.

21 January 2018

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Assembly and activation of neurotrophic factor receptor complexes

21 January 2018

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An extended surface of binding to Trk tyrosine kinase receptors in NGF and BDNF allows the engineering of a multifunctional pan-neurotrophin.

20 November 2024

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Expression of the neurotrophin receptor TrkA down-regulates expression and function of angiogenic stimulators in SH-SY5Y neuroblastoma cells

20 November 2024

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Molecular and biochemical characterization of the human trk proto-oncogene

20 November 2024

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Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum

20 November 2024

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Ligand-independent oligomerization of cell-surface erythropoietin receptor is mediated by the transmembrane domain

20 November 2024

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The single transmembrane domains of human receptor tyrosine kinases encode self-interactions

20 November 2024

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20 November 2024

Identifiers

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13 September 2017

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