Nerve growth factor activation of the extracellular signal-regulated kinase pathway is modulated by Ca(2 ) and calmodulin. (Q39584779)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10688641 AND SRC:MED&resulttype=core&format=json

4 November 2019

title

Nerve growth factor activation of the extracellular signal-regulated kinase pathway is modulated by Ca(2 ) and calmodulin (English)

1 reference

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4 November 2019

6

1 reference

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4 November 2019

author name string

J Egea

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10688641 AND SRC:MED&resulttype=core&format=json

4 November 2019

C Espinet

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10688641 AND SRC:MED&resulttype=core&format=json

4 November 2019

R M Soler

3

1 reference

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4 November 2019

S Peiró

4

1 reference

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4 November 2019

N Rocamora

5

1 reference

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4 November 2019

language of work or name

English

0 references

publication date

1 March 2000

1 reference

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Molecular and Cellular Biology

4 November 2019

published in

1 reference

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4 November 2019

volume

20

1 reference

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4 November 2019

issue

6

1 reference

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4 November 2019

page(s)

1931-1946

1 reference

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Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

4 November 2019

cites work

1 reference

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The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

14 September 2017

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RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs

14 September 2017

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Nerve Growth Factor Activates Extracellular Signal-Regulated Kinase and p38 Mitogen-Activated Protein Kinase Pathways To Stimulate CREB Serine 133 Phosphorylation

14 September 2017

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A Dominant-Negative Inhibitor of CREB Reveals that It Is a General Mediator of Stimulus-Dependent Transcription of c-fos

14 September 2017

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Calmodulin activates phosphatidylinositol 3-kinase

14 September 2017

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Phosphorylation of Raf-1 Serine 338-Serine 339 Is an Essential Regulatory Event for Ras-Dependent Activation and Biological Signaling

14 September 2017

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Phosphatidylinositol 3-Kinase Is Required for Integrin-Stimulated AKT and Raf-1/Mitogen-Activated Protein Kinase Pathway Activation

14 September 2017

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The complexity of Raf-1 regulation

14 September 2017

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Mitogen-activated protein kinase pathways

14 September 2017

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Signal transduction from multiple Ras effectors

14 September 2017

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RIC, a calmodulin-binding Ras-like GTPase

14 September 2017

1 reference

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Regulation of mitogen-activated protein kinases by a calcium/calmodulin-dependent protein kinase cascade

14 September 2017

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Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins

14 September 2017

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Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase

14 September 2017

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Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylation

14 September 2017

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Transforming potentials of epidermal growth factor and nerve growth factor receptors inversely correlate with their phospholipase C gamma affinity and signal activation

14 September 2017

1 reference

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Stimulation of growth factor receptor signal transduction by activation of voltage-sensitive calcium channels

14 September 2017

1 reference

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Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

14 September 2017

1 reference

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Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

14 September 2017

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An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro

14 September 2017

1 reference

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Reconstitution of the Raf-1-MEK-ERK signal transduction pathway in vitro

14 September 2017

1 reference

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Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2

14 September 2017

1 reference

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Molecular structure of a protein-tyrosine/threonine kinase activating p42 mitogen-activated protein (MAP) kinase: MAP kinase kinase

14 September 2017

1 reference

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Identification of Trk binding sites for SHC and phosphatidylinositol 3'-kinase and formation of a multimeric signaling complex

14 September 2017

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Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1

14 September 2017

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Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses

14 September 2017

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Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene.

14 September 2017

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Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons

14 September 2017

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A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

14 September 2017

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The mitogen-activated protein kinase cascade is activated by B-Raf in response to nerve growth factor through interaction with p21ras

14 September 2017

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Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

14 September 2017

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How MAP kinases are regulated

14 September 2017

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Interleukin-2 triggers a novel phosphatidylinositol 3-kinase-dependent MEK activation pathway

14 September 2017

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SNT, a Differentiation-Specific Target of Neurotrophic Factor-Induced Tyrosine Kinase Activity in Neurons and PC12 Cells

14 September 2017

1 reference

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A synthetic inhibitor of the mitogen-activated protein kinase cascade

14 September 2017

1 reference

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Regulation of Raf-1 and Raf-1 mutants by Ras-dependent and Ras-independent mechanisms in vitro

14 September 2017

1 reference

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Protein tyrosine kinase PYK2 involved in Ca(2 )-induced regulation of ion channel and MAP kinase functions

14 September 2017

1 reference

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Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation

14 September 2017

1 reference

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PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

14 September 2017

1 reference

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N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation

14 September 2017

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Insulin-stimulated microtubule-associated protein kinase is phosphorylated on tyrosine and threonine in vivo

14 September 2017

1 reference

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Effect of a dominant inhibitory Ha-ras mutation on neuronal differentiation of PC12 cells

14 September 2017

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ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

14 September 2017

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Evidence for a Ras-dependent extracellular signal-regulated protein kinase (ERK) cascade

14 September 2017

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Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

14 September 2017

1 reference

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Activation of phosphatidylinositol 3-kinase by epidermal growth factor, basic fibroblast growth factor, and nerve growth factor in PC12 pheochromocytoma cells

14 September 2017

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Regulation and role of brain calcium/calmodulin-dependent protein kinase II.

14 September 2017

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Activation of the MAP kinase pathway by the protein kinase raf

14 September 2017

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The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

14 September 2017

1 reference

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Raf-1 activates MAP kinase-kinase

14 September 2017

1 reference

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Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

14 September 2017

1 reference

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Cellular components of nerve growth factor signaling

14 September 2017

1 reference

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The role of neurotrophins in the developing nervous system

14 September 2017

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Alterations in the surface properties of cells responsive to nerve growth factor

14 September 2017

1 reference

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Calcium influx activates extracellular-regulated kinase/mitogen-activated protein kinase pathway through a calmodulin-sensitive mechanism in PC12 cells

14 September 2017

1 reference

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Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway

25 September 2017

1 reference

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Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues.

25 September 2017

1 reference

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Calmodulin modulates mitogen-activated protein kinase activation in response to membrane depolarization in PC12 cells

25 September 2017

1 reference

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Ca(2 )-dependent routes to Ras: mechanisms for neuronal survival, differentiation, and plasticity?

25 September 2017

1 reference

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Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras.

25 September 2017

1 reference

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Physiology of the neurotrophins

25 September 2017

1 reference

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TrkA mediates the nerve growth factor-induced intracellular calcium accumulation.

25 September 2017

1 reference

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MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases?

25 September 2017

1 reference

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Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF.

25 September 2017

1 reference

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Purification of a new neurotrophic factor from mammalian brain

25 September 2017

1 reference

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Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling

25 September 2017

1 reference

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Mechanisms and consequences of activation of protein kinase B/Akt

15 June 2018

1 reference

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Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

15 June 2018

1 reference

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Action of the neurotrophins on calcium uptake

15 June 2018

1 reference

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A Role for Ca 2 /Calmodulin-Dependent Protein Kinase II in the Mitogen-Activated Protein Kinase Signaling Cascade of Cultured Rat Aortic Vascular Smooth Muscle Cells

15 June 2018

1 reference

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Evidence for MEK-independent pathways regulating the prolonged activation of the ERK-MAP kinases

15 June 2018

1 reference

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Both p140(trk) and p75(NGFR) nerve growth factor receptors mediate nerve growth factor-stimulated calcium uptake

15 June 2018

1 reference

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Interleukin-8 regulation of the Ras/Raf/mitogen-activated protein kinase pathway in human neutrophils

15 June 2018

1 reference

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Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras.

15 June 2018

1 reference

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Multimers of anionic amphiphiles mimic calmodulin stimulation of cyclic nucleotide phosphodiesterase

15 June 2018

1 reference

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Nerve growth factor and K-252a increase catecholamine release from PC12 cells

15 June 2018

1 reference

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Trifluoperazine binding to porcine brain calmodulin and skeletal muscle troponin C.

15 June 2018

1 reference

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Ionic events induced by epidermal growth factor. Evidence that hyperpolarization and stimulated cation influx play a role in the stimulation of cell growth

15 June 2018

1 reference

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Ras controls coupling of growth factor receptors and protein kinase C in the membrane to Raf-1 and B-Raf protein serine kinases in the cytosol

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110811

Activation of phosphatidylinositol-3 kinase by nerve growth factor involves indirect coupling of the trk proto-oncogene with src homology 2 domains

15 June 2018

1 reference

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Activation of Ras by insulin in 3T3 L1 cells does not involve GTPase-activating protein phosphorylation

15 June 2018

1 reference

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ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110811

Development of survival responsiveness to brain-derived neurotrophic factor, neurotrophin 3 and neurotrophin 4/5, but not to nerve growth factor, in cultured motoneurons from chick embryo spinal cord.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110811

Calmodulin inhibitor W13 induces sustained activation of ERK2 and expression of p21(cip1).

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110811

Depolarization and neurotrophins converge on the phosphatidylinositol 3-kinase-Akt pathway to synergistically regulate neuronal survival

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110811

Activation of phosphatidylinositol 3-kinase, but not extracellular-regulated kinases, is necessary to mediate brain-derived neurotrophic factor-induced motoneuron survival

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110811

Conditional inhibition of the mitogen-activated protein kinase cascade by wortmannin. Dependence on signal strength

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110811

Skeletal muscle-derived trophic factors prevent motoneurons from entering an active cell death program in vitro.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110811

An improved method detects differential NGF and BDNF gene expression in response to depolarization in cultured hippocampal neurons

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110811

Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

21 August 2018

1 reference

12 December 2020

Neurotrophic factors and their receptors

1 reference

12 December 2020

Nerve growth factor-induced increase in calcium uptake by PC12 cells

1 reference

12 December 2020

Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases

1 reference

12 December 2020

Multiple Ca2 signaling pathways converge on CaM kinase in PC12 cells

1 reference

12 December 2020

Intracellular calcium levels regulate the actions of nerve growth factor on calcium uptake in PC12 cells

1 reference

12 December 2020

The calmodulin antagonist calmidazolium stimulates release of nitric oxide in neuroblastoma N1E-115 cells

1 reference

12 December 2020

Inhibition by the calmodulin antagonist trifluoperazine of experimental hepatocarcinogenesis induced by N-nitrosomorpholine in Sprague-Dawley rats

1 reference

12 December 2020

Calcium influx induces neurite growth through a Src-Ras signaling cassette

1 reference

12 December 2020

Differential regulation of Raf isozymes by growth versus differentiation inducing factors in PC12 pheochromocytoma cells

1 reference

12 December 2020

Identification of an essential signaling cascade for mitogen-activated protein kinase activation by angiotensin II in cultured rat vascular smooth muscle cells. Possible requirement of Gq-mediated p21ras activation coupled to a Ca2 /calmodulin-sensi

1 reference

12 December 2020

1 reference

12 December 2020

Role of calcium-sensitive tyrosine kinase Pyk2/CAKbeta/RAFTK in angiotensin II induced Ras/ERK signaling

1 reference

12 December 2020

Oncogenes, growth factors and phorbol esters regulate Raf-1 through common mechanisms

1 reference

12 December 2020

Involvement of PYK2 in angiotensin II signaling of vascular smooth muscle cells

1 reference

12 December 2020

Proliferation, differentiation and degeneration in the spinal ganglia of the chick embryo under normal and experimental conditions

1 reference

12 December 2020

Update: PtdIns(3,4,5)P 3 Gets Its Message Across

1 reference

12 December 2020

Critical Role of Calcium- dependent Epidermal Growth Factor Receptor Transactivation in PC12 Cell Membrane Depolarization and Bradykinin Signaling

1 reference

12 December 2020

Calmodulin Is Involved in Membrane Depolarization-Mediated Survival of Motoneurons by Phosphatidylinositol-3 Kinase- and MAPK-Independent Pathways

1 reference

12 December 2020

High affinity calmodulin target sequence in the signalling molecule PI 3‐kinase

1 reference

12 December 2020

Characterization and isolation of proteolytically modified nerve growth factor

1 reference

12 December 2020

Hydrophobic regions function in calmodulin-enzyme(s) interactions

1 reference

12 December 2020

Naphthalenesulfonamides as calmodulin antagonists

1 reference

12 December 2020

Early rise of cytosolic Ca2 induced by NGF in PC12 and chromaffin cells

1 reference

12 December 2020

K-252a inhibits the increase in c-fos transcription and the increase in intracellular calcium produced by nerve growth factor in PC12 cells

1 reference

12 December 2020

10.1128/MCB.20.6.1931-1946.2000

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10688641 AND SRC:MED&resulttype=core&format=json

4 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10688641 AND SRC:MED&resulttype=core&format=json

4 November 2019

PubMed publication ID

10688641

1 reference