Cyclic 3',5'-guanosine monophosphate-dependent protein kinase inhibits colon cancer cell adaptation to hypoxia. (Q39544460)

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31 January 2020

title

Cyclic 3',5'-guanosine monophosphate-dependent protein kinase inhibits colon cancer cell adaptation to hypoxia (English)

1 reference

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31 January 2020

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6

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31 January 2020

author name string

In-Kiu Kwon

1

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31 January 2020

Rui Wang

2

1 reference

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31 January 2020

Nikhil Prakash

3

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31 January 2020

Renee Bozard

4

1 reference

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31 January 2020

Troy A Baudino

5

1 reference

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31 January 2020

Muthusamy Thangaraju

7

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31 January 2020

Zheng Dong

8

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31 January 2020

Darren D Browning

9

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31 January 2020

language of work or name

English

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publication date

11 May 2011

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31 January 2020

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31 January 2020

volume

117

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31 January 2020

issue

23

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31 January 2020

page(s)

5282-5293

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Protein kinase G as a therapeutic target for the treatment of metastatic colorectal cancer

31 January 2020

cites work

1 reference

cGMP-Dependent Protein Kinases as Potential Targets for Colon Cancer Prevention and Treatment

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Cyclic GMP-dependent protein kinases: understanding in vivo functions by gene targeting

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Cyclic nucleotide-dependent protein kinases: intracellular receptors for cAMP and cGMP action

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Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells

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Suppression of cyclic GMP-specific phosphodiesterase 5 promotes apoptosis and inhibits growth in HT29 cells

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Exisulind, a selective apoptotic antineoplastic drug

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Activation of protein kinase G Increases the expression of p21CIP1, p27KIP1, and histidine triad protein 1 through Sp1.

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PKG inhibits TCF signaling in colon cancer cells by blocking beta-catenin expression and activating FOXO4.

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A role for cyclic-GMP dependent protein kinase in anoikis

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Expression of cyclic guanosine monophosphate-dependent protein kinase in metastatic colon carcinoma cells blocks tumor angiogenesis

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Functional analysis of type 1alpha cGMP-dependent protein kinase using green fluorescent fusion proteins

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PIASy stimulates HIF1α SUMOylation and negatively regulates HIF1α activity in response to hypoxia

21 January 2018

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Casein kinase 1 regulates human hypoxia-inducible factor HIF-1.

21 January 2018

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Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia

21 January 2018

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Interplay between VHL/HIF1alpha and Wnt/beta-catenin pathways during colorectal tumorigenesis

21 January 2018

1 reference

Invited review: cGMP-dependent protein kinase signaling mechanisms in smooth muscle: from the regulation of tone to gene expression.

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Antiangiogenic therapy: a universal chemosensitization strategy for cancer?

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Why do tumors become resistant to antiangiogenesis drugs?

1 reference