Roles of AKT1 and AKT2 in non‐small cell lung cancer cell survival, growth, and migration (Q39514532)

12 September 2017

title

Roles of AKT1 and AKT2 in non-small cell lung cancer cell survival, growth, and migration (English)

1 reference

12 September 2017

Roles of AKT1 and AKT2 in non‐small cell lung cancer cell survival, growth, and migration (English)

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

non-small-cell lung carcinoma

6 December 2024

main subject

1 reference

1 reference

Myoung W. Lee

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21722267

6 December 2024

Dae S. Kim

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21722267

6 December 2024

Joo H. Lee

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21722267

6 December 2024

Bum S. Lee

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21722267

6 December 2024

Soo H. Lee

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21722267

6 December 2024

Hye L. Jung

6

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6 December 2024

Ki W. Sung

7

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6 December 2024

Heung T. Kim

8

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6 December 2024

Keon H. Yoo

9

1 reference

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6 December 2024

Hong H. Koo

10

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6 December 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21722267

6 December 2024

publication date

5 August 2011

1 reference

full work available at URL

12 September 2017

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111/j.1349-7006.2011.02025.x

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1349-7006.2011.02025.x

6 December 2024

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

6 December 2024

1 reference

12 September 2017

volume

102

1 reference

12 September 2017

issue

10

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12 September 2017

page(s)

1822-1828

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Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy

12 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Activation of the Akt survival pathway contributes to TRAIL resistance in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Overexpression of phospho-eIF4E is associated with survival through AKT pathway in non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Akt is activated in chronic lymphocytic leukemia cells and delivers a pro-survival signal: the therapeutic potential of Akt inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Targeting fibroblast growth factor receptors blocks PI3K/AKT signaling, induces apoptosis, and impairs mammary tumor outgrowth and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Substrate-bound insulin-like growth factor (IGF)-I-IGF binding protein-vitronectin-stimulated breast cell migration is enhanced by coactivation of the phosphatidylinositide 3-Kinase/AKT pathway by alphav-integrins and the IGF-I receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

PTEN regulates angiogenesis through PI3K/Akt/VEGF signaling pathway in human pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Exploring the gain of function contribution of AKT to mammary tumorigenesis in mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Overexpression of Akt converts radial growth melanoma to vertical growth melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Advances in protein kinase B signalling: AKTion on multiple fronts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Akt isoform-specific inhibition of MDA-MB-231 cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Akt1 and akt2 play distinct roles in the initiation and metastatic phases of mammary tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Akt1 and Akt2 differently regulate muscle creatine kinase and myogenin gene transcription in insulin-induced differentiation of C2C12 myoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Phosphorylation and regulation of Raf by Akt (protein kinase B)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

MKP1 repression is required for the chemosensitizing effects of NF-kappaB and PI3K inhibitors to cisplatin in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Cell stress and MEKK1-mediated c-Jun activation modulate NFkappaB activity and cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Targeting apoptosis in solid tumors: the role of bortezomib from preclinical to clinical evidence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Ablation of Akt2 Induces Autophagy through Cell Cycle Arrest, the Downregulation of p70S6K, and the Deregulation of Mitochondria in MDA-MB231 Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

High glucose promotes retinal endothelial cell migration through activation of Src, PI3K/Akt1/eNOS, and ERKs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

AKT2 is frequently upregulated in HER-2/neu-positive breast cancers and may contribute to tumor aggressiveness by enhancing cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Akt2 overexpression plays a critical role in the establishment of colorectal cancer metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Activated Akt1 accelerates MMTV-c-ErbB2 mammary tumourigenesis in mice without activation of ErbB3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Optimization of patient selection for gefitinib in non-small cell lung cancer by combined analysis of epidermal growth factor receptor mutation, K-ras mutation, and Akt phosphorylation

21 January 2018

13

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Isoform-specific regulation of adipocyte differentiation by Akt/protein kinase Bα

6 December 2024

21

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Negative regulation of ERK and Elk by protein kinase B modulates c-Fos transcription

6 December 2024

29

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Akt1 inhibition by RNA interference sensitizes human non-small cell lung cancer cells to cisplatin

6 December 2024

30

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

Opposing Roles for Akt1 and Akt2 in Rac/Pak Signaling and Cell Migration

6 December 2024

35

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2011.02025.X

6 December 2024

Identifiers

1 reference

National Center for Biotechnology Information

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21722267

6 December 2024

1 reference