Pharmacodynamic Analysis of a Serine Protease Inhibitor, MK-4519, against Hepatitis C Virus Using a NovelIn VitroPharmacodynamic System (Q39430698)

11 September 2017

Pharmacodynamic analysis of a serine protease inhibitor, MK-4519, against hepatitis C virus using a novel in vitro pharmacodynamic system (English)

1 reference

https://api.crossref.org/works/10.1128/AAC.05383-11

11 September 2017

Pharmacodynamic Analysis of a Serine Protease Inhibitor, MK-4519, against Hepatitis C Virus Using a NovelIn VitroPharmacodynamic System (English)

1 reference

19 December 2024

1 reference

1 reference

4

Robert Kulawy

1 reference

11 September 2017

9

Arnold Louie

1 reference

11 September 2017

10

George L Drusano

1 reference

11 September 2017

1

Ashley N. Brown

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22155837

19 December 2024

author name string

James J. McSharry

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22155837

19 December 2024

Jonathan R. Adams

3

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19 December 2024

Robert Kulawy

4

1 reference

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19 December 2024

Richard J. O. Barnard

5

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19 December 2024

W. Newhard

6

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19 December 2024

A. Corbin

7

1 reference

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19 December 2024

Daria J. Hazuda

8

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19 December 2024

language of work or name

English

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publication date

12 December 2011

1 reference

full work available at URL

11 September 2017

https://aac.asm.org/content/aac/56/3/1170.full.pdf

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22155837

https://europepmc.org/articles/PMC3294889

19 December 2024

file format

HyperText Markup Language

online access status

open access

content deliverer

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https://europepmc.org/articles/PMC3294889?pdf=render

19 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22155837

https://doi.org/10.1128/aac.05383-11

19 December 2024

online access status

open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22155837

https://journals.asm.org/doi/pdf/10.1128/AAC.05383-11

19 December 2024

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Antimicrobial Agents and Chemotherapy

19 December 2024

published in

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11 September 2017

56

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11 September 2017

3

1 reference

11 September 2017

1170-1181

1 reference

Zanamivir, at 600 Milligrams Twice Daily, Inhibits Oseltamivir-Resistant 2009 Pandemic H1N1 Influenza Virus in an In Vitro Hollow-Fiber Infection Model System

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1 reference

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Effect of half-life on the pharmacodynamic index of zanamivir against influenza virus delineated by a mathematical model

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1 reference

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1 reference

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1 reference

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Diagnosis, management, and treatment of hepatitis C: an update

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1 reference

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1 reference

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Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of the hepatitis C virus

11 September 2017

1 reference

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11 September 2017

1 reference

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1 reference

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VX-950, a Novel Hepatitis C Virus (HCV) NS3-4A Protease Inhibitor, Exhibits Potent Antiviral Activities in HCV Replicon Cells

11 September 2017

1 reference

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Production of infectious genotype 1a hepatitis C virus (Hutchinson strain) in cultured human hepatoma cells

11 September 2017

1 reference

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Pharmacodynamics of abacavir in an in vitro hollow-fiber model system

11 September 2017

1 reference

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Hollow-fiber unit evaluation of a new human immunodeficiency virus type 1 protease inhibitor, BMS-232632, for determination of the linked pharmacodynamic variable

11 September 2017

1 reference

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Preclinical Characterization of BI 201335, a C-Terminal Carboxylic Acid Inhibitor of the Hepatitis C Virus NS3-NS4A Protease

11 September 2017

1 reference

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14 September 2017

1 reference

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The novel nucleoside analog R1479 (4'-azidocytidine) is a potent inhibitor of NS5B-dependent RNA synthesis and hepatitis C virus replication in cell culture

14 September 2017

1 reference

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14 September 2017

1 reference

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15 June 2018

1 reference

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21 August 2018

1 reference

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21 August 2018

1 reference

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21 August 2018

1 reference

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In vitro resistance studies of hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061: structural analysis indicates different resistance mechanisms

21 August 2018

1 reference

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21 August 2018

Identifiers

DOI

10.1128/AAC.05383-11

1 reference

11 September 2017

1 reference

11 September 2017

1 reference