IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA. (Q39422225)

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7 January 2020

title

IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA (English)

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7

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Jahangir Iqbal

1

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3

Tracie Seimon

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author name string

Kezhi Dai

2

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Rivka Jungreis

4

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Miho Oyadomari

5

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George Kuriakose

6

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Ira Tabas

8

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M Mahmood Hussain

9

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publication date

1 May 2008

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volume

7

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issue

5

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page(s)

445-455

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Acquisition of triacylglycerol transfer activity by microsomal triglyceride transfer protein during evolution

7 January 2020

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1 reference

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MTP regulated by an alternate promoter is essential for NKT cell development

11 September 2017

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Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia

11 September 2017

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RNA-quality control by the exosome

11 September 2017

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11 September 2017

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Coactivation of Foxa2 through Pgc-1beta promotes liver fatty acid oxidation and triglyceride/VLDL secretion

11 September 2017

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Control of mRNA stability in eukaryotes

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The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.

11 September 2017

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11 September 2017

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Activation of peroxisome proliferator-activated receptor alpha increases the expression and activity of microsomal triglyceride transfer protein in the liver

11 September 2017

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ARP-1/COUP-TF II determines hepatoma phenotype by acting as both a transcriptional repressor of microsomal triglyceride transfer protein and an inducer of CYP7A1

11 September 2017

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Microsomal triglyceride transfer protein: a multifunctional protein

11 September 2017

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Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet.

11 September 2017

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Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly

11 September 2017

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IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

11 September 2017

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XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

11 September 2017

1 reference

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Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice

11 September 2017

1 reference

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Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress

11 September 2017

1 reference

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The role of the microsomal triglygeride transfer protein in abetalipoproteinemia

11 September 2017

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Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

11 September 2017

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A deficiency of microsomal triglyceride transfer protein reduces apolipoprotein B secretion

11 September 2017

1 reference

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Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

11 September 2017

1 reference

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A proposed model for the assembly of chylomicrons

11 September 2017

1 reference

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Cloning of mammalian Ire1 reveals diversity in the ER stress responses

11 September 2017

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Knockout of the abetalipoproteinemia gene in mice: reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes.

11 September 2017

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Mutations of the microsomal triglyceride-transfer-protein gene in abetalipoproteinemia

11 September 2017

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Secretion of apolipoprotein B-containing lipoproteins from HeLa cells is dependent on expression of the microsomal triglyceride transfer protein and is regulated by lipid availability

11 September 2017

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11 September 2017

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Transcriptional regulation of human and hamster microsomal triglyceride transfer protein genes. Cell type-specific expression and response to metabolic regulators

11 September 2017

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11 September 2017

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14 September 2017

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Microsomal triglyceride transfer protein, the abetalipoproteinemia gene product, mediates the secretion of apolipoprotein B-containing lipoproteins from heterologous cells

25 September 2017

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A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response

25 September 2017

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Hepatic overexpression of microsomal triglyceride transfer protein (MTP) results in increased in vivo secretion of VLDL triglycerides and apolipoprotein B.

15 June 2018

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Phospholipid transfer activity of microsomal triacylglycerol transfer protein is sufficient for the assembly and secretion of apolipoprotein B lipoproteins

15 June 2018

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Determining hepatic triglyceride production in mice: comparison of poloxamer 407 with Triton WR-1339.

21 August 2018

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Evidence for multiple complementary pathways for efficient cholesterol absorption in mice

21 August 2018

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Bile acid reduces the secretion of very low density lipoprotein by repressing microsomal triglyceride transfer protein gene expression mediated by hepatocyte nuclear factor-4.

21 August 2018

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A simple, rapid, and sensitive fluorescence assay for microsomal triglyceride transfer protein.

21 August 2018

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Multiple, independently regulated pathways of cholesterol transport across the intestinal epithelial cells

21 August 2018

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A Drosophila microsomal triglyceride transfer protein homolog promotes the assembly and secretion of human apolipoprotein B. Implications for human and insect transport and metabolism.

21 August 2018

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Genetic analysis of cholesterol accumulation in inbred mice

21 August 2018

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An MTP inhibitor that normalizes atherogenic lipoprotein levels in WHHL rabbits

21 August 2018

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12 December 2020

Assembly and secretion of chylomicrons by differentiated Caco-2 cells. Nascent triglycerides and preformed phospholipids are preferentially used for lipoprotein assembly

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12 December 2020

Mutations in MTP gene in abeta- and hypobeta-lipoproteinemia

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12 December 2020

Transfer of cholesteryl esters and phospholipids as well as net deposition by microsomal triglyceride transfer protein

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12 December 2020

Mechanisms involved in vitamin E transport by primary enterocytes and in vivo absorption

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10.1016/J.CMET.2008.03.005

Identifiers

DOI

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7 January 2020

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7 January 2020

PubMed publication ID

18460335

1 reference