Role of DISC1 in Neuronal Trafficking and its Implication in Neuropsychiatric Manifestation and Neurotherapeutics. (Q39406264)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28664299 AND SRC:MED&resulttype=core&format=json

24 March 2020

review article

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title

Role of DISC1 in Neuronal Trafficking and its Implication in Neuropsychiatric Manifestation and Neurotherapeutics (English)

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24 March 2020

2

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24 March 2020

Toshifumi Tomoda

series ordinal

1

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24 March 2020

author name string

Takeshi Sakurai

series ordinal

3

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24 March 2020

language of work or name

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1 July 2017

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24 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28664299 AND SRC:MED&resulttype=core&format=json

24 March 2020

volume

14

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24 March 2020

issue

3

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24 March 2020

page(s)

623-629

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Aggregation of scaffolding protein DISC1 dysregulates phosphodiesterase 4 in Huntington's disease

24 March 2020

cites work

1 reference

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Regulation of mitochondrial dynamics by DISC1, a putative risk factor for major mental illness

10 July 2018

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Disrupted-in-schizophrenia 1 (DISC1) and Syntaphilin collaborate to modulate axonal mitochondrial anchoring

10 July 2018

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Utility and validity of DISC1 mouse models in biological psychiatry

10 July 2018

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Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits.

10 July 2018

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Early postnatal GABAA receptor modulation reverses deficits in neuronal maturation in a conditional neurodevelopmental mouse model of DISC1.

10 July 2018

1 reference

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Interneuronal DISC1 regulates NRG1-ErbB4 signalling and excitatory-inhibitory synapse formation in the mature cortex

10 July 2018

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DISC1 Protein Regulates γ-Aminobutyric Acid, Type A (GABAA) Receptor Trafficking and Inhibitory Synaptic Transmission in Cortical Neurons.

10 July 2018

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Excitatory/Inhibitory Balance and Circuit Homeostasis in Autism Spectrum Disorders

10 July 2018

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Evaluating historical candidate genes for schizophrenia

10 July 2018

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Disrupted-in-schizophrenia-1 (DISC1) Regulates Endoplasmic Reticulum Calcium Dynamics.

10 July 2018

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Cellular functions of the amyloid precursor protein from development to dementia

10 July 2018

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DISC1 regulates trafficking and processing of APP and Aβ generation.

10 July 2018

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Synaptic dysregulation in a human iPS cell model of mental disorders

10 July 2018

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PAKs inhibitors ameliorate schizophrenia-associated dendritic spine deterioration in vitro and in vivo during late adolescence

10 July 2018

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DISC1 complexes with TRAK1 and Miro1 to modulate anterograde axonal mitochondrial trafficking

10 July 2018

1 reference

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Regulation of N-methyl-D-aspartate receptors by disrupted-in-schizophrenia-1.

10 July 2018

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DISC1-ATF4 transcriptional repression complex: dual regulation of the cAMP-PDE4 cascade by DISC1.

10 July 2018

1 reference

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A Disc1 mutation differentially affects neurites and spines in hippocampal and cortical neurons

10 July 2018

1 reference

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DISC1: a key lead in studying cortical development and associated brain disorders

10 July 2018

1 reference

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Mitochondria as sensors and regulators of calcium signalling

10 July 2018

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The dendritic tree and brain disorders.

10 July 2018

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Linking neurodevelopmental and synaptic theories of mental illness through DISC1

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5509643

Altered axonal targeting and short-term plasticity in the hippocampus of Disc1 mutant mice.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5509643

Molecular characterization of disrupted in schizophrenia-1 risk variant S704C reveals the formation of altered oligomeric assembly.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5509643

DISC1 regulates synaptic vesicle transport via a lithium-sensitive pathway

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5509643

Meta-analysis indicates that common variants at the DISC1 locus are not associated with schizophrenia

10 July 2018

1 reference

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DISC1-dependent switch from progenitor proliferation to migration in the developing cortex

10 July 2018

1 reference

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Trafficking Kinesin Protein (TRAK)-mediated Transport of Mitochondria in Axons of Hippocampal Neurons

10 July 2018

1 reference

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DISC1 and Huntington's disease--overlapping pathways of vulnerability to neurological disorder?

10 July 2018

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The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function.

10 July 2018

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The cell biology of synaptic inhibition in health and disease

10 July 2018

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Delivery of GABAARs to synapses is mediated by HAP1-KIF5 and disrupted by mutant huntingtin.

10 July 2018

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Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

10 July 2018

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Slc25a12 disruption alters myelination and neurofilaments: a model for a hypomyelination syndrome and childhood neurodevelopmental disorders

10 July 2018

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The mechanism of Ca2 -dependent regulation of kinesin-mediated mitochondrial motility

10 July 2018

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Insolubility of disrupted-in-schizophrenia 1 disrupts oligomer-dependent interactions with nuclear distribution element 1 and is associated with sporadic mental disease

10 July 2018

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DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1

10 July 2018

1 reference

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Disrupted-in-schizophrenia-1 (DISC1): a key susceptibility factor for major mental illnesses

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5509643

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5509643

A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5509643

The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5509643

Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth

10 July 2018

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Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth

10 July 2018

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Shanghai declaration on promoting health in the 2030 Agenda for Sustainable Development

10 July 2018

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DISC1 a key molecular lead in psychiatry and neurodevelopment: No-More Disrupted-in-Schizophrenia 1.

21 August 2018

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DISC1-dependent Regulation of Mitochondrial Dynamics Controls the Morphogenesis of Complex Neuronal Dendrites

21 August 2018

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NEURODEVELOPMENT. Adult cortical plasticity depends on an early postnatal critical period

21 August 2018

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Disrupted-in-schizophrenia 1 regulates transport of ITPR1 mRNA for synaptic plasticity

21 August 2018

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A dopamine D2 receptor-DISC1 protein complex may contribute to antipsychotic-like effects

21 August 2018

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Molecular motor KIF5A is essential for GABA(A) receptor transport, and KIF5A deletion causes epilepsy

21 August 2018

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Disrupted in Schizophrenia 1 forms pathological aggresomes that disrupt its function in intracellular transport.

21 August 2018

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Disrupted in Schizophrenia-1 regulates intracellular trafficking of mitochondria in neurons

21 August 2018

1 reference

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Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses.

21 August 2018

1 reference

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Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1.

21 August 2018

1 reference

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10.1007/S13311-017-0556-5

21 August 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28664299 AND SRC:MED&resulttype=core&format=json

24 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28664299 AND SRC:MED&resulttype=core&format=json

24 March 2020

PubMed publication ID

28664299

1 reference