Filarial Abundant Larval Transcript Protein ALT-2: An Immunomodulatory Therapeutic Agent for Type 1 Diabetes. (Q39388911)

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9 April 2020

title

Filarial Abundant Larval Transcript Protein ALT-2: An Immunomodulatory Therapeutic Agent for Type 1 Diabetes (English)

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9 April 2020

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9 April 2020

Vishal Khatri

4

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9 April 2020

author name string

Pooja M Reddy

2

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9 April 2020

Nitin Amdare

3

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Aaditya Tarnekar

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Kalyan Goswami

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Maryada Venkata Rami Reddy

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publication date

7 June 2016

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Indian journal of clinical biochemistry

9 April 2020

published in

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volume

32

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issue

1

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page(s)

45-52

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Brugia malayi soluble and excretory-secretory proteins attenuate development of streptozotocin-induced type 1 diabetes in mice

9 April 2020

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Heterologous expression of the filarial nematode alt gene products reveals their potential to inhibit immune function

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The Secreted Larval Acidic Proteins (SLAPs) of Onchocerca spp. are encoded by orthologues of the alt gene family of Brugia malayi and have host protective potential.

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A novel therapeutic approach targeting articular inflammation using the filarial nematode-derived phosphorylcholine-containing glycoprotein ES-62.

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Treatment of Mild Hypoglycemia

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Heligmosomoides polygyrus infection reduces severity of type 1 diabetes induced by multiple low-dose streptozotocin in mice via STAT6- and IL-10-independent mechanisms

21 August 2018

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Inhibition of type 1 diabetes in filaria-infected non-obese diabetic mice is associated with a T helper type 2 shift and induction of FoxP3 regulatory T cells

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Effect of schistosoma mansoni egg deposition on multiple low doses streptozotocin induced insulin dependent diabetes.

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A factor of inducing IgE from a filarial parasite prevents insulin-dependent diabetes mellitus in nonobese diabetic mice

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Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

21 January 2018

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Infection with Schistosoma mansoni prevents insulin dependent diabetes mellitus in non-obese diabetic mice

21 January 2018

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Prevention of type 1 diabetes through infection with an intestinal nematode parasite requires IL-10 in the absence of a Th2-type response

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28149012

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S12291-016-0572-Y

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28149012 AND SRC:MED&resulttype=core&format=json

9 April 2020

1 reference

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9 April 2020

PubMed publication ID

28149012

1 reference