The helicase HAGE expressed by malignant melanoma-initiating cells is required for tumor cell proliferation in vivo. (Q39384751)

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25 January 2020

title

The helicase HAGE expressed by malignant melanoma-initiating cells is required for tumor cell proliferation in vivo (English)

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25 January 2020

1

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25 January 2020

Amanda K. Miles

3

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25 January 2020

Stephanie Mcardle

5

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25 January 2020

Tarik Regad

6

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25 January 2020

author name string

Morgan G Mathieu

2

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25 January 2020

Robert C Rees

4

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25 January 2020

language of work or name

English

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publication date

5 March 2012

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Journal of Biological Chemistry

25 January 2020

number of pages

11

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based on heuristic

inferred from page(s)

published in

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25 January 2020

volume

287

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25 January 2020

issue

17

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25 January 2020

page(s)

13633-13643

1 reference

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From unwinding to clamping - the DEAD box RNA helicase family

25 January 2020

cites work

1 reference

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ABCB5 identifies a therapy-refractory tumor cell population in colorectal cancer patients

11 September 2017

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RNA Helicases p68 and p72: Multifunctional Proteins with Important Implications for Cancer Development

11 September 2017

1 reference

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VEGFR-1 expressed by malignant melanoma-initiating cells is required for tumor growth

11 September 2017

1 reference

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The RNA helicase database

11 September 2017

1 reference

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Role of RAS in the regulation of PI 3-kinase

11 September 2017

1 reference

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Cancer/testis antigen CAGE exerts negative regulation on p53 expression through HDAC2 and confers resistance to anti-cancer drugs

11 September 2017

1 reference

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The cancer/testis antigen CAGE with oncogenic potential stimulates cell proliferation by up-regulating cyclins D1 and E in an AP-1- and E2F-dependent manner

11 September 2017

1 reference

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The RNA helicase p68 is a novel androgen receptor coactivator involved in splicing and is overexpressed in prostate cancer

11 September 2017

1 reference

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P68 RNA helicase (DDX5) alters activity of cis- and trans-acting factors of the alternative splicing of H-Ras

11 September 2017

1 reference

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Role of CAGE, a novel cancer/testis antigen, in various cellular processes, including tumorigenesis, cytolytic T lymphocyte induction, and cell motility.

11 September 2017

1 reference

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Identification of cells initiating human melanomas

11 September 2017

1 reference

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Dynamic FoxO transcription factors

11 September 2017

1 reference

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Dead-box proteins: a family affair--active and passive players in RNP-remodeling

11 September 2017

1 reference

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DExD/H box RNA helicases: multifunctional proteins with important roles in transcriptional regulation

11 September 2017

1 reference

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CAGE, a novel cancer/testis antigen gene, promotes cell motility by activation ERK and p38 MAPK and downregulating ROS.

11 September 2017

1 reference

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The DEAD-box protein family of RNA helicases

11 September 2017

1 reference

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Signaling interplay in Ras superfamily function

11 September 2017

1 reference

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ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340133

Oncogenic Ras in tumour progression and metastasis

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340133

The Ras superfamily at a glance

11 September 2017

1 reference

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Oncogenic Ras and its role in tumor cell invasion and metastasis

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340133

DExD/H-box proteins and their partners: helping RNA helicases unwind

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340133

Targeting RAS signalling pathways in cancer therapy

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340133

Decreased proliferation of human melanoma cell lines caused by antisense RNA against translation factor eIF-4A1.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340133

Role of glycogen synthase kinase-3 in cancer: regulation by Wnts and other signaling pathways

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340133

Helicase structure and mechanism

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340133

Cell signaling by receptor tyrosine kinases

11 September 2017

1 reference

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Identification on a human sarcoma of two new genes with tumor-specific expression

11 September 2017

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Understanding Ras: 'it ain't over 'til it's over'.

11 September 2017

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The rck/p54 candidate proto-oncogene product is a 54-kilodalton D-E-A-D box protein differentially expressed in human and mouse tissues

11 September 2017

1 reference

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ras oncogenes in human cancer: a review

11 September 2017

1 reference

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Zebrafish embryo extracts promote sphere-forming abilities of human melanoma cell line.

11 September 2017

1 reference

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Mitogen-activated protein kinases, Erk and p38, phosphorylate and regulate Foxo1.

14 September 2017

1 reference

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Growth factors rescue cutaneous melanoma cells from apoptosis induced by knockdown of mutated (V 600 E) B-RAF.

14 September 2017

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A panel of cancer-testis genes exhibiting broad-spectrum expression in haematological malignancies.

14 September 2017

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Multi-talented DEAD-box proteins and potential tumor promoters: p68 RNA helicase (DDX5) and its paralog, p72 RNA helicase (DDX17)

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340133

HAGE, a cancer/testis antigen expressed at the protein level in a variety of cancers.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340133

Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340133

Overexpression and poly-ubiquitylation of the DEAD-box RNA helicase p68 in colorectal tumours.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340133

Overexpression of a DEAD box protein (DDX1) in neuroblastoma and retinoblastoma cell lines

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340133

The DDX1 gene maps within 400 kbp 5' to MYCN and is frequently coamplified in human neuroblastoma

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22393060

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M111.308973

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22393060 AND SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22393060 AND SRC:MED&resulttype=core&format=json

25 January 2020

PubMed publication ID

22393060

1 reference