DNA Damage and Repair Biomarkers of Immunotherapy Response (Q39384263)

8 January 2018

review article

1 reference

title

DNA Damage and Repair Biomarkers of Immunotherapy Response (English)

1 reference

8 January 2018

0 references

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1 reference

Kent W Mouw

1

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8 January 2018

Michael S Goldberg

series ordinal

2

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8 January 2018

Panagiotis A Konstantinopoulos

series ordinal

3

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8 January 2018

Alan D D'Andrea

series ordinal

4

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8 January 2018

language of work or name

1 reference

19 June 2017

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8 January 2018

published in

Cancer Discovery

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8 January 2018

volume

7

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8 January 2018

issue

7

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8 January 2018

page(s)

675-693

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8 January 2018

Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance.

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15 June 2018

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Effector T Cells Abrogate Stroma-Mediated Chemoresistance in Ovarian Cancer

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15 June 2018

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Immune Checkpoint Inhibition for Hypermutant Glioblastoma Multiforme Resulting From Germline Biallelic Mismatch Repair Deficiency.

15 June 2018

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Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma

15 June 2018

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Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial

15 June 2018

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Agonist-Mediated Activation of STING Induces Apoptosis in Malignant B Cells

15 June 2018

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Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

15 June 2018

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Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints.

15 June 2018

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Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy

15 June 2018

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Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer

15 June 2018

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15 June 2018

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15 June 2018

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15 June 2018

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STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity

15 June 2018

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STING: infection, inflammation and cancer

15 June 2018

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Targeting the DNA Damage Response in Cancer

15 June 2018

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IDO Downregulation Induces Sensitivity to Pemetrexed, Gemcitabine, FK866, and Methoxyamine in Human Cancer Cells

15 June 2018

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Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1.

15 June 2018

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A systematic evaluation of abscopal responses following radiotherapy in patients with metastatic melanoma treated with ipilimumab

15 June 2018

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Comprehensive cancer-gene panels can be used to estimate mutational load and predict clinical benefit to PD-1 blockade in clinical practice.

15 June 2018

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Repair Pathway Choices and Consequences at the Double-Strand Break

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15 June 2018

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Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

15 June 2018

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Association of Polymerase e-Mutated and Microsatellite-Instable Endometrial Cancers With Neoantigen Load, Number of Tumor-Infiltrating Lymphocytes, and Expression of PD-1 and PD-L1

15 June 2018

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Mismatch Repair-Deficient Cancers Are Targets for Anti-PD-1 Therapy.

15 June 2018

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CTLA-4 Blockade Synergizes Therapeutically with PARP Inhibition in BRCA1-Deficient Ovarian Cancer

15 June 2018

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Local radiotherapy and granulocyte-macrophage colony-stimulating factor to generate abscopal responses in patients with metastatic solid tumours: a proof-of-principle trial.

15 June 2018

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The PARP1 inhibitor BMN 673 exhibits immunoregulatory effects in a Brca1(-/-) murine model of ovarian cancer

15 June 2018

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PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

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Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

15 June 2018

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15 June 2018

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Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity

15 June 2018

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15 June 2018

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15 June 2018

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15 June 2018

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15 June 2018

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Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

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DNA damage primes the type I interferon system via the cytosolic DNA sensor STING to promote anti-microbial innate immunity

15 June 2018

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A unique subset of epithelial ovarian cancers with platinum sensitivity and PARP inhibitor resistance

15 June 2018

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15 June 2018

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High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4 T cells in human melanoma

15 June 2018

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Stereotactic Radiation Therapy Augments Antigen-Specific PD-1-Mediated Antitumor Immune Responses via Cross-Presentation of Tumor Antigen

15 June 2018

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PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma

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15 June 2018

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15 June 2018

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Genetic basis for clinical response to CTLA-4 blockade in melanoma

15 June 2018

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15 June 2018

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15 June 2018

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Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy

15 June 2018

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Inflammation-driven carcinogenesis is mediated through STING

15 June 2018

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Somatic ERCC2 mutations correlate with cisplatin sensitivity in muscle-invasive urothelial carcinoma

15 June 2018

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DNA damage and innate immunity: links and trade-offs

15 June 2018

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Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia

15 June 2018

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Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing

15 June 2018

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Identification and validation of an anthracycline/cyclophosphamide-based chemotherapy response assay in breast cancer

15 June 2018

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Discovery and saturation analysis of cancer genes across 21 tumour types

15 June 2018

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Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice.

15 June 2018

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Towards the introduction of the 'Immunoscore' in the classification of malignant tumours

15 June 2018

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The causes and consequences of genetic heterogeneity in cancer evolution

15 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Up-regulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8( ) T cells

15 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

15 June 2018

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cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.

15 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Integrated genomic characterization of endometrial carcinoma

15 June 2018

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Synergistic effect of CTLA-4 blockade and cancer chemotherapy in the induction of anti-tumor immunity

15 June 2018

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Replication stress links structural and numerical cancer chromosomal instability

15 June 2018

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DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking

15 June 2018

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Durable cancer regression off-treatment and effective reinduction therapy with an anti-PD-1 antibody

15 June 2018

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Regulatory T cells in radiotherapeutic responses

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Comprehensive molecular characterization of human colon and rectal cancer

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Recurrent hemizygous deletions in cancers may optimize proliferative potential

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

CTLA-4 blockade expands infiltrating T cells and inhibits cancer cell repopulation during the intervals of chemotherapy in murine mesothelioma.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: results from a randomized, double-blind, multicenter phase II study.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Combining immunotherapy and targeted therapies in cancer treatment

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Immunologic correlates of the abscopal effect in a patient with melanoma

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Chemotherapeutics and radiation stimulate MHC class I expression through elevated interferon-beta signaling in breast cancer cells

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

BRCA1 and BRCA2 mutations correlate with TP53 abnormalities and presence of immune cell infiltrates in ovarian high-grade serous carcinoma.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Cancer immunotherapy comes of age

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

The DNA Damage Response Induces IFN

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Type I interferon is selectively required by dendritic cells for immune rejection of tumors

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Ipilimumab plus dacarbazine for previously untreated metastatic melanoma

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Doxorubicin downregulates cell surface B7-H1 expression and upregulates its nuclear expression in breast cancer cells: role of B7-H1 as an anti-apoptotic molecule

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Cyclophosphamide enhances immunity by modulating the balance of dendritic cell subsets in lymphoid organs

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

DNA Damage, Aging, and Cancer

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Chemotherapeutic agents in noncytotoxic concentrations increase antigen presentation by dendritic cells via an IL-12-dependent mechanism

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Phase III trial comparing concurrent biochemotherapy with cisplatin, vinblastine, dacarbazine, interleukin-2, and interferon alfa-2b with cisplatin, vinblastine, and dacarbazine alone in patients with metastatic malignant melanoma (E3695): a trial c

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

T-cell responses to survivin in cancer patients undergoing radiation therapy

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

The role of MYH and microsatellite instability in the development of sporadic colorectal cancer

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Type, density, and location of immune cells within human colorectal tumors predict clinical outcome

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

MGMT gene silencing and benefit from temozolomide in glioblastoma

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Cytosine arabinoside induces costimulatory molecule expression in acute myeloid leukemia cells.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

The three Es of cancer immunoediting

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Gastric cancers of the microsatellite mutator phenotype display characteristic genetic and clinical features

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Results of interleukin-2-based treatment in advanced melanoma: a case record-based analysis of 631 patients.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

The effects of therapeutic irradiation on lymphocytes and immunity

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

STING Pathway Activation Stimulates Potent Immunity against Acute Myeloid Leukemia

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Reliable Detection of Mismatch Repair Deficiency in Colorectal Cancers Using Mutational Load in Next-Generation Sequencing Panels

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Radiation and checkpoint blockade immunotherapy: radiosensitisation and potential mechanisms of synergy

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Mismatch repair status and clinical outcome in endometrial cancer: a systematic review and meta-analysis.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Radiation as an immunological adjuvant: current evidence on dose and fractionation.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

High-dose interleukin-2 for the treatment of metastatic renal cell carcinoma : a retrospective analysis of response and survival in patients treated in the surgery branch at the National Cancer Institute between 1986 and 2006.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Mutational signature analysis identifies MUTYH deficiency in colorectal cancers and adrenocortical carcinomas.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Evolution of Neoantigen Landscape during Immune Checkpoint Blockade in Non-Small Cell Lung Cancer

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Acquired resistance to immunotherapy and future challenges

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

DNA repair, genome stability and cancer: a historical perspective

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Decitabine Enhances Lymphocyte Migration and Function and Synergizes with CTLA-4 Blockade in a Murine Ovarian Cancer Model.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Whole-genome characterization of chemoresistant ovarian cancer

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Acquired resistance to fractionated radiotherapy can be overcome by concurrent PD-L1 blockade

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

TGFβ inhibition prior to hypofractionated radiation enhances efficacy in preclinical models

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

An abscopal response to radiation and ipilimumab in a patient with metastatic non-small cell lung cancer.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Bacillus calmette-guerin versus chemotherapy for the intravesical treatment of patients with carcinoma in situ of the bladder: a meta-analysis of the published results of randomized clinical trials

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Reduced frequencies and suppressive function of CD4 CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Inhibition of CD4( )25 T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Cancer immunotherapy based on mutation-specific CD4 T cells in a patient with epithelial cancer

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Ipilimumab in combination with paclitaxel and carboplatin as first-line therapy in extensive-disease-small-cell lung cancer: results from a randomized, double-blind, multicenter phase 2 trial

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659200

Cell adhesion molecules mediate radiation-induced leukocyte adhesion to the vascular endothelium

4 November 2018

1 reference

12 December 2020

Whole body irradiation; radiobiology or medicine?

1 reference

12 December 2020

Intraepithelial T cells and prognosis in ovarian carcinoma: novel associations with stage, tumor type and BRCA1 loss

1 reference

12 December 2020

Development of tumor-infiltrating lymphocytes in breast cancer after neoadjuvant paclitaxel chemotherapy

1 reference

12 December 2020

Irradiation of tumor cells up-regulates Fas and enhances CTL lytic activity and CTL adoptive immunotherapy

1 reference

12 December 2020

Differential impairment of regulatory T cells rather than effector T cells by paclitaxel-based chemotherapy

1 reference

12 December 2020

Radiotherapy promotes tumor-specific effector CD8 T cells via dendritic cell activation

1 reference

12 December 2020

Tumor-infiltrating lymphocytes are a marker for microsatellite instability in colorectal carcinoma

1 reference

12 December 2020

An interesting case of possible abscopal effect in malignant melanoma

1 reference

12 December 2020

10.1158/2159-8290.CD-17-0226

Identifiers

DOI

1 reference

8 January 2018

PMC publication ID

5659200

1 reference

8 January 2018

PubMed publication ID

28630051

1 reference

8 January 2018