MicroRNA-21 inhibitor sensitizes human glioblastoma U251 stem cells to chemotherapeutic drug temozolomide (Q39359970)

11 September 2017

title

MicroRNA-21 inhibitor sensitizes human glioblastoma U251 stem cells to chemotherapeutic drug temozolomide (English)

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11 September 2017

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Shuguang Zhang

1

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11 September 2017

Yi Wan

2

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11 September 2017

Tianhong Pan

3

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11 September 2017

Xiaoyan Gu

4

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11 September 2017

Chunfa Qian

5

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11 September 2017

Guan Sun

6

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11 September 2017

Lihua Sun

7

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11 September 2017

Yangzheng Xiang

8

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11 September 2017

Zhimin Wang

9

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11 September 2017

Lei Shi

10

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11 September 2017

publication date

19 April 2012

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Journal of Molecular Neuroscience

11 September 2017

published in

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11 September 2017

volume

47

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11 September 2017

issue

2

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11 September 2017

page(s)

346-356

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Randomized phase II study of temozolomide and radiotherapy compared with radiotherapy alone in newly diagnosed glioblastoma multiforme

11 September 2017

cites work

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Temozolomide preferentially depletes cancer stem cells in glioblastoma

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The expression of a new variant of the pro-apoptotic molecule Bax, Baxpsi, is correlated with an increased survival of glioblastoma multiforme patients

21 January 2018

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MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells

21 January 2018

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Real-time quantification of microRNAs by stem-loop RT-PCR

21 January 2018

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Effective sensitization of temozolomide by ABT-888 is lost with development of temozolomide resistance in glioblastoma xenograft lines

21 January 2018

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Dexamethasone protected human glioblastoma U87MG cells from temozolomide induced apoptosis by maintaining Bax:Bcl-2 ratio and preventing proteolytic activities

21 January 2018

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Stem cell division is regulated by the microRNA pathway

21 January 2018

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Apoptotic proteins in the temporal cortex in schizophrenia: high Bax/Bcl-2 ratio without caspase-3 activation

21 January 2018

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The let-7 microRNA represses cell proliferation pathways in human cells

21 January 2018

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Prognostic significance of the immunohistochemical staining of cleaved caspase-3, an activated form of caspase-3, in gliomas

21 January 2018

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MiR-21 indicates poor prognosis in tongue squamous cell carcinomas as an apoptosis inhibitor

21 January 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

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The small organic compound HA14-1 prevents Bcl-2 interaction with Bax to sensitize malignant glioma cells to induction of cell death.

21 January 2018

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MicroRNA polymorphisms: the future of pharmacogenomics, molecular epidemiology and individualized medicine

21 January 2018

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MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells

21 January 2018

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BMPRII is a direct target of miR-21.

21 January 2018

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MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol

21 January 2018

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Co-delivery of as-miR-21 and 5-FU by poly(amidoamine) dendrimer attenuates human glioma cell growth in vitro

21 January 2018

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Pharmacogenomics genes show varying perceptibility to microRNA regulation.

21 January 2018

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Regulation and function of the p53 tumor suppressor protein

21 January 2018

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hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells

21 January 2018

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MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity

21 January 2018

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MicroRNAs and pharmacogenomics

21 January 2018

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High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

21 January 2018

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Cyclin-dependent kinase 1-mediated Bcl-xL/Bcl-2 phosphorylation acts as a functional link coupling mitotic arrest and apoptosis

21 January 2018

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Chemotherapy of human malignant glioma: prevention of efficacy by dexamethasone?

21 January 2018

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MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms

21 January 2018

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https://api.crossref.org/works/10.1007/S12031-012-9759-8

Metronomic treatment of temozolomide inhibits tumor cell growth through reduction of angiogenesis and augmentation of apoptosis in orthotopic models of gliomas.

21 January 2018

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12 December 2020

Bcl-2 and Bcl-xL in peroxide-resistant A549 and U87MG cells

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12 December 2020

Increased Bax/Bcl-2 ratio up-regulates caspase-3 and increases apoptosis in the thymus of patients with myasthenia gravis

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12 December 2020

Annexin V staining during reperfusion detects cardiomyocytes with unique properties

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12 December 2020

p53 effects both the duration of G2/M arrest and the fate of temozolomide-treated human glioblastoma cells

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12 December 2020

Ezrin-dependent promotion of glioma cell clonogenicity, motility, and invasion mediated by BCL-2 and transforming growth factor-beta2.

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12 December 2020

Expression level of Bcl-2 determines anti- or proapoptotic function.

1 reference

12 December 2020

10.1007/S12031-012-9759-8

Identifiers

DOI

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11 September 2017

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