Tracking sphingosine metabolism and transport in sphingolipidoses: NPC1 deficiency as a test case (Q39346215)

11 September 2017

title

Tracking sphingosine metabolism and transport in sphingolipidoses: NPC1 deficiency as a test case (English)

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11 September 2017

5

Elina Ikonen

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11 September 2017

Tomas Blom

1

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11 September 2017

Zaiguo Li

series ordinal

2

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11 September 2017

Robert Bittman

series ordinal

3

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11 September 2017

Pentti Somerharju

series ordinal

4

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11 September 2017

language of work or name

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11 June 2012

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11 September 2017

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11 September 2017

volume

13

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11 September 2017

issue

9

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11 September 2017

page(s)

1234-1243

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The cell biology of lysosomal storage disorders

11 September 2017

cites work

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https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Common and uncommon pathogenic cascades in lysosomal storage diseases

21 January 2018

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https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

A view on sphingolipids and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Use of D-erythro-sphingosine as a pharmacological inhibitor of protein kinase C in human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Sphingolipid topology and the dynamic organization and function of membrane proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Sphingosine-induced apoptosis is dependent on lysosomal proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Lipids on trial: the search for the offending metabolite in Niemann-Pick type C disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

An Overview of Sphingolipid Metabolism: From Synthesis to Breakdown

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Cellular pathology of Niemann-Pick type C disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Identification of surface residues on Niemann-Pick C2 essential for hydrophobic handoff of cholesterol to NPC1 in lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Free sphingoid bases in tissues from patients with type C Niemann-Pick disease and other lysosomal storage disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium

21 January 2018

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https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Sphingosine 1-phosphate lyase enzyme assay using a BODIPY-labeled substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Principles of bioactive lipid signalling: lessons from sphingolipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Improvement in lipid and protein trafficking in Niemann-Pick C1 cells by correction of a secondary enzyme defect

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Endocytic trafficking of sphingomyelin depends on its acyl chain length

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Niemann-Pick type C disease: novel NPC1 mutations and characterization of the concomitant acid sphingomyelinase deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Defective endocytic trafficking of NPC1 and NPC2 underlying infantile Niemann-Pick type C disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Cholesterol modulates membrane traffic along the endocytic pathway in sphingolipid-storage diseases

21 January 2018

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https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

The multigenic sphingomyelin synthase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Cholesterol overload promotes morphogenesis of a Niemann-Pick C (NPC)-like compartment independent of inhibition of NPC1 or HE1/NPC2 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

FTY720 stimulates 27-hydroxycholesterol production and confers atheroprotective effects in human primary macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Type C Niemann-Pick disease: a murine model of the lysosomal cholesterol lipidosis accumulates sphingosine and sphinganine in liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Modulation of protein kinase C by endogenous sphingosine: inhibition of phorbol dibutyrate binding in Niemann–Pick C fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Endosomal lipid accumulation in NPC1 leads to inhibition of PKC, hypophosphorylation of vimentin and Rab9 entrapment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Regulation of protein kinase C by sphingosine and lysosphingolipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Activation of acid sphingomyelinase by protein kinase Cdelta-mediated phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1600-0854.2012.01379.X

10.1111/J.1600-0854.2012.01379.X

21 January 2018

Identifiers

DOI

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11 September 2017

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