Interactions between N and C termini of α1C subunit regulate inactivation of CaV1.2 L-type Ca(2 ) channel (Q39328112)

11 September 2017

Interactions between N and C termini of α1C subunit regulate inactivation of CaV1.2 L-type Ca(2 ) channel (English)

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11 September 2017

Adva Benmocha Guggenheimer

1

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11 September 2017

Lior Almagor

2

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11 September 2017

Vladimir Tsemakhovich

3

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11 September 2017

Debi Ranjan Tripathy

4

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11 September 2017

Joel A Hirsch

5

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11 September 2017

Nathan Dascal

6

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11 September 2017

17 November 2015

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11 September 2017

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11 September 2017

10

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11 September 2017

1

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11 September 2017

55-68

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Calmodulin regulation (calmodulation) of voltage-gated calcium channels

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Mechanisms of a human skeletal myotonia produced by mutation in the C-terminus of NaV1.4: is Ca2 regulation defective?

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Domain-domain interactions in ion channels

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Apo states of calmodulin and CaBP1 control CaV1 voltage-gated calcium channel function through direct competition for the IQ domain

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

The calmodulin-binding, short linear motif, NSCaTE is conserved in L-type channel ancestors of vertebrate Cav1.2 and Cav1.3 channels

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Structural insights into neuronal K channel-calmodulin complexes

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

The role of a voltage-dependent Ca2 channel intracellular linker: a structure-function analysis

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Structural basis for the regulation of L-type voltage-gated calcium channels: interactions between the N-terminal cytoplasmic domain and Ca2 -calmodulin

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Progress in the structural understanding of voltage-gated calcium channel (CaV) function and modulation

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Multiple C-terminal tail Ca(2 )/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerization

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Interplay of voltage and Ca-dependent inactivation of L-type Ca current.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Structures of CaV2 Ca2 /CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Regulation of maximal open probability is a separable function of Ca(v)beta subunit in L-type Ca2 channel, dependent on NH2 terminus of alpha1C (Ca(v)1.2alpha).

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Insights into voltage-gated calcium channel regulation from the structure of the CaV1.2 IQ domain-Ca2 /calmodulin complex

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Modulation of CaV1.2 channels by Mg2 acting at an EF-hand motif in the COOH-terminal domain

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Voltage- and calcium-dependent inactivation in high voltage-gated Ca(2 ) channels

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Molecular mechanism for divergent regulation of Cav1.2 Ca2 channels by calmodulin and Ca2 -binding protein-1

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Molecular determinants of Ca(2 )/calmodulin-dependent regulation of Ca(v)2.1 channels

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Mechanism of calcium/calmodulin inhibition of rod cyclic nucleotide-gated channels

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Solution structure of Ca(2 )-calmodulin reveals flexible hand-like properties of its domains

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Structure and regulation of voltage-gated Ca2 channels

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Calmodulin: a prototypical calcium sensor

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Ca2 -induced inhibition of the cardiac Ca2 channel depends on calmodulin

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Mutations in the EF-hand motif impair the inactivation of barium currents of the cardiac alpha1C channel

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Feedback inhibition of Ca2 channels by Ca2 depends on a short sequence of the C terminus that does not include the Ca2 -binding function of a motif with similarity to Ca2 -binding domains

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Mechanism of local and global Ca2 sensing by calmodulin in complex with a Ca2 channel

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

A modular switch for spatial Ca2 selectivity in the calmodulin regulation of CaV channels.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Functional stoichiometry and local enrichment of calmodulin interacting with Ca2 channels

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Calmodulin bifurcates the local Ca2 signal that modulates P/Q-type Ca2 channels.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Essential Ca(2 )-binding motif for Ca(2 )-sensitive inactivation of L-type Ca2 channels

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Conservation of Ca2 /calmodulin regulation across Na and Ca2 channels.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Crystal structure of the CaV2 IQ domain in complex with Ca2 /calmodulin: high-resolution mechanistic implications for channel regulation by Ca2

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Recruitment of Gβγ controls the basal activity of G-protein coupled inwardly rectifying potassium (GIRK) channels: crucial role of distal C terminus of GIRK1.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Structural analyses of Ca²⁺/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Regulation of Neuronal M-Channel Gating in an Isoform-Specific Manner: Functional Interplay between Calmodulin and Syntaxin 1A

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Characterization of the calmodulin-binding site in the N terminus of CaV1.2.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Identification of the components controlling inactivation of voltage-gated Ca2 channels

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Molecular basis of calmodulin tethering and Ca2 -dependent inactivation of L-type Ca2 channels

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Calmodulin supports both inactivation and facilitation of L-type calcium channels

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Interdomain Interactions Underlying Activation of Cyclic Nucleotide-Gated Channels

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4802761

Modulation of L-type Ca2 Channels by Gβγ and Calmodulin via Interactions with N and C Termini of α1C

21 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1080/19336950.2015.1108499

Ca2 -sensitive inactivation and facilitation of L-type Ca2 channels both depend on specific amino acid residues in a consensus calmodulin-binding motif in the(alpha)1C subunit

21 January 2018

1 reference

12 December 2020

Calmodulin is the Ca2 sensor for Ca2 -dependent inactivation of L-type calcium channels

1 reference

12 December 2020

Regulation of voltage-gated Ca2 channels by calmodulin

1 reference

12 December 2020

Determinants for calmodulin binding on voltage-dependent Ca2 channels

1 reference

12 December 2020

Interactions of calmodulin with the multiple binding sites of Cav1.2 Ca2 channels

1 reference

12 December 2020

Interactions of calmodulin with two peptides derived from the c-terminal cytoplasmic domain of the Ca(v)1.2 Ca2 channel provide evidence for a molecular switch involved in Ca2 -induced inactivation

1 reference

12 December 2020

Voltage-gated mobility of the Ca2 channel cytoplasmic tails and its regulatory role

1 reference

12 December 2020

The alpha1B Ca2 channel amino terminus contributes determinants for beta subunit-mediated voltage-dependent inactivation properties

1 reference

12 December 2020

10.1080/19336950.2015.1108499

Identifiers

DOI

1 reference

11 September 2017

1 reference

11 September 2017

PubMed publication ID

26577286

1 reference