Identification of unbalanced genome copy number abnormalities in patients with multiple myeloma by single-nucleotide polymorphism genotyping microarray analysis. (Q39280199)

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scientific article published on 13 September 2012

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English	Identification of unbalanced genome copy number abnormalities in patients with multiple myeloma by single-nucleotide polymorphism genotyping microarray analysis.	scientific article published on 13 September 2012

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scholarly article

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13 February 2020

Identification of unbalanced genome copy number abnormalities in patients with multiple myeloma by single-nucleotide polymorphism genotyping microarray analysis (English)

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13 February 2020

single-nucleotide polymorphism

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multiple myeloma

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Kazumi Suzukawa

6

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13 February 2020

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Shigeru Chiba

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13 February 2020

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Yuhei Kamada

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13 February 2020

Mamiko Sakata-Yanagimoto

2

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13 February 2020

Masashi Sanada

3

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13 February 2020

Aiko Sato-Otsubo

4

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13 February 2020

Terukazu Enami

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13 February 2020

Naoki Kurita

7

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13 February 2020

Hidekazu Nishikii

8

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13 February 2020

Yasuhisa Yokoyama

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13 February 2020

Yasushi Okoshi

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13 February 2020

Yuichi Hasegawa

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13 February 2020

Seishi Ogawa

12

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13 February 2020

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13 September 2012

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13 February 2020

International Journal of Hematology

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13 February 2020

96

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13 February 2020

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13 February 2020

492-500

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13 February 2020

Genetic heterogeneity in multiple myeloma.

1 reference

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Genetic events in the pathogenesis of multiple myeloma

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Molecular pathogenesis and a consequent classification of multiple myeloma

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Clinical and biologic implications of recurrent genomic aberrations in myeloma

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A SNP microarray and FISH-based procedure to detect allelic imbalances in multiple myeloma: an integrated genomics approach reveals a wide gene dosage effect

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A robust algorithm for copy number detection using high-density oligonucleotide single nucleotide polymorphism genotyping arrays

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Genetics and cytogenetics of multiple myeloma: a workshop report

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Relationship of patient survival and chromosome anomalies detected in metaphase and/or interphase cells at diagnosis of myeloma.

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Both hypodiploidy and deletion of chromosome 13 independently confer poor prognosis in multiple myeloma

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Deletions of CDKN2C in multiple myeloma: biological and clinical implications

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CKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through SKP2- and p27Kip1-dependent and -independent mechanisms

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Amplification and overexpression of CKS1B at chromosome band 1q21 is associated with reduced levels of p27Kip1 and an aggressive clinical course in multiple myeloma

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Genome-wide loss of heterozygosity and copy number analysis in melanoma using high-density single-nucleotide polymorphism arrays.

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Signalling and survival pathways in multiple myeloma

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Analysis of IL-6-mediated growth control of myeloma cells using a gp130 chimeric receptor approach

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Methylation status of fragile histidine triad (FHIT) gene and its clinical impact on prognosis of patients with multiple myeloma

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TGFbetaR2 aberrant methylation is a potential prognostic marker and therapeutic target in multiple myeloma.

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Prognostic value of cytogenetics in multiple myeloma

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21 January 2018

Prognostic value of chromosome 1q21 gain by fluorescent in situ hybridization and increase CKS1B expression in myeloma

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Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma

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Hypodiploidy is a major prognostic factor in multiple myeloma

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Deletion of 13q14 remains an independent adverse prognostic variable in multiple myeloma despite its frequent detection by interphase fluorescence in situ hybridization

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Interphase fluorescence in situ hybridization (FISH) as a powerful tool for the detection of aneuploidy in multiple myeloma

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A catalog of genes homozygously deleted in human lung cancer and the candidacy of PTPRD as a tumor suppressor gene.

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Multiple myeloma primary cells show a highly rearranged unbalanced genome with amplifications and homozygous deletions irrespective of the presence of immunoglobulin-related chromosome translocations

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Identifiers

10.1007/S12185-012-1171-1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22972171 AND SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22972171 AND SRC:MED&resulttype=core&format=json

13 February 2020

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