Prion protein facilitates uptake of zinc into neuronal cells (Q39258090)

10 September 2017

Prion protein facilitates uptake of zinc into neuronal cells (English)

1 reference

10 September 2017

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7

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10 September 2017

Jo V Rushworth

5

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Talitha L Kerrigan

object named as

Talitha L Kerrigan

3

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author name string

Nicole T Watt

1

1 reference

10 September 2017

David R Taylor

2

1 reference

10 September 2017

Heledd H Griffiths

4

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10 September 2017

Isobel J Whitehouse

6

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10 September 2017

language of work or name

English

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publication date

1 January 2012

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10 September 2017

Nature Communications

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10 September 2017

3

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10 September 2017

1134

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

10 September 2017

start time

1 January 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Zinc modulates copper coordination mode in prion protein octa-repeat subdomains

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Zinc transporter ZnT-3 regulates presynaptic Erk1/2 signaling and hippocampus-dependent memory

10 September 2017

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Interaction between human prion protein and amyloid-beta (Abeta) oligomers: role OF N-terminal residues

10 September 2017

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Zinc in the physiology and pathology of the CNS.

10 September 2017

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Evolutionary descent of prion genes from the ZIP family of metal ion transporters

10 September 2017

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Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers

10 September 2017

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The prion's elusive reason for being

10 September 2017

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Physiology of the prion protein

10 September 2017

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The role of the GluR2 subunit in AMPA receptor function and synaptic plasticity.

10 September 2017

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Cellular prion protein regulates beta-secretase cleavage of the Alzheimer's amyloid precursor protein

10 September 2017

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Zinc is a novel intracellular second messenger

10 September 2017

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Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

10 September 2017

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Copper and the prion protein: methods, structures, function, and disease

10 September 2017

1 reference

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Mammalian zinc transport, trafficking, and signals

10 September 2017

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New insights into prion structure and toxicity.

10 September 2017

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Assigning functions to distinct regions of the N-terminus of the prion protein that are involved in its copper-stimulated, clathrin-dependent endocytosis

10 September 2017

1 reference

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The neurobiology of zinc in health and disease

10 September 2017

1 reference

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Overview of mammalian zinc transporters

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

The prion protein and neuronal zinc homeostasis

10 September 2017

1 reference

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Cell-surface prion protein interacts with glycosaminoglycans

10 September 2017

1 reference

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Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice

10 September 2017

1 reference

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Functions of zinc in signaling, proliferation and differentiation of mammalian cells

10 September 2017

1 reference

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Copper stimulates endocytosis of the prion protein

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

A transmembrane form of the prion protein in neurodegenerative disease

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Prion disease associated with a novel nine octapeptide repeat insertion in the PRNP gene.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Zinc coordination, function, and structure of zinc enzymes and other proteins

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

A nine amino acid domain is essential for mutant prion protein toxicity

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

alpha-cleavage of the prion protein occurs in a late compartment of the secretory pathway and is independent of lipid rafts

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Prion protein amyloidosis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

The prion protein is a combined zinc and copper binding protein: Zn2 alters the distribution of Cu2 coordination modes

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Prion protein with an octapeptide insertion has impaired neuroprotective activity in transgenic mice

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Role of zinc influx via AMPA/kainate receptor activation in metabotropic glutamate receptor-mediated calcium release

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Cellular prion protein localization in rodent and primate brain

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Rapid induction of Alzheimer A beta amyloid formation by zinc.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Release of endogenous Zn2 from brain tissue during activity

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Fatal familial insomnia and familial Creutzfeldt-Jakob disease: disease phenotype determined by a DNA polymorphism

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Knockout of Zn transporters Zip-1 and Zip-3 attenuates seizure-induced CA1 neurodegeneration.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Prion protein is reduced in aging and in sporadic but not in familial Alzheimer's disease.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

A role for synaptic zinc in activity-dependent Abeta oligomer formation and accumulation at excitatory synapses.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Mutant prion protein expression causes motor and memory deficits and abnormal sleep patterns in a transgenic mouse model.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Prion protein regulates glutamate-dependent lactate transport of astrocytes.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Protein tyrosine phosphatase inhibition reduces degeneration of dopaminergic substantia nigra neurons and projections in 6-OHDA treated adult rats

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

The low-density lipoprotein receptor-related protein 1 (LRP1) mediates the endocytosis of the cellular prion protein

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Exocytosis of vesicular zinc reveals persistent depression of neurotransmitter release during metabotropic glutamate receptor long-term depression at the hippocampal CA3-CA1 synapse.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Visualization of transmitter release with zinc fluorescence detection at the mouse hippocampal mossy fibre synapse

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Zn2 currents are mediated by calcium-permeable AMPA/kainate channels in cultured murine hippocampal neurones.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Identification of the heparan sulfate binding sites in the cellular prion protein

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Aberrant metal binding by prion protein in human prion disease.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Fluorescent sensors for Zn(2 ) based on a fluorescein platform: synthesis, properties and intracellular distribution

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Ablation of the metal ion-induced endocytosis of the prion protein by disease-associated mutation of the octarepeat region

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Sensitivity of AMPA receptors to pentobarbital

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Prion protein expression level alters regional copper, iron and zinc content in the mouse brain

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493655

Is loss of function of the prion protein the cause of prion disorders?

2 December 2018

1 reference

12 December 2020

Method for identifying neuronal cells suffering zinc toxicity by use of a novel fluorescent sensor

1 reference

12 December 2020

Phosphotyrosyl-protein phosphatase. Specific inhibition by Zn

1 reference

12 December 2020

Copper and zinc promote interactions between membrane-anchored peptides of the metal binding domain of the prion protein

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS2135

1 reference

10 September 2017

0 references

1 reference

10 September 2017

PubMed publication ID

23072804

1 reference