The Cul4A-DDB1 E3 ubiquitin ligase complex represses p73 transcriptional activity. (Q39255653)

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15 February 2020

title

The Cul4A-DDB1 E3 ubiquitin ligase complex represses p73 transcriptional activity (English)

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15 February 2020

2

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15 February 2020

Douglas R. Green

6

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15 February 2020

Alexander V. Garabadgiu

8

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15 February 2020

author name string

M Malatesta

1

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15 February 2020

E M Memmi

3

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15 February 2020

J Zhang

4

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15 February 2020

A Antonov

5

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N A Barlev

7

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P Zhou

9

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G Melino

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F Bernassola

11

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15 February 2020

language of work or name

English

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publication date

22 October 2012

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15 February 2020

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15 February 2020

volume

32

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issue

39

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page(s)

4721-4726

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UV-damaged DNA-binding proteins are targets of CUL-4A-mediated ubiquitination and degradation

15 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

DDB1 targets Chk1 to the Cul4 E3 ligase complex in normal cycling cells and in cells experiencing replication stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

DCAFs, the missing link of the CUL4-DDB1 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

DDB1 is essential for genomic stability in developing epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

Myc protein is stabilized by suppression of a novel E3 ligase complex in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

Regulation of DNA damage response pathways by the cullin-RING ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

Deletion of DDB1 in mouse brain and lens leads to p53-dependent elimination of proliferating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

Proliferation defects and genome instability in cells lacking Cul4A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

p73 is a simian [correction of human] p53-related protein that can induce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

p73 Induces apoptosis via PUMA transactivation and Bax mitochondrial translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

The ubiquitin-protein ligase Itch regulates p73 stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

Cul4A physically associates with MDM2 and participates in the proteolysis of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

Regulation of transcriptional activation domain function by ubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

Enhancement of CIITA transcriptional function by ubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

NAD(P)H quinone oxidoreductase protects TAp63gamma from proteasomal degradation and regulates TAp63gamma-dependent growth arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

L2DTL/CDT2 and PCNA interact with p53 and regulate p53 polyubiquitination and protein stability through MDM2 and CUL4A/DDB1 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

NF-kappaB inhibits T-cell activation-induced, p73-dependent cell death by induction of MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

New antibodies recognizing p73: comparison with commercial antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/ONC.2012.463

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.463

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23085759 AND SRC:MED&resulttype=core&format=json

release_fxbaf46uu5ckvk42j4mksy5q4e

15 February 2020

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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