Genetics of inflammatory bowel disease: beyond NOD2. (Q39238723)

10 September 2017

title

Genetics of inflammatory bowel disease: beyond NOD2. (English)

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inflammatory bowel diseases

10 September 2017

main subject

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author name string

Maša Umićević Mirkov

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28404137 AND SRC:MED&resulttype=core&format=json

5 June 2020

publication date

9 February 2017

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The lancet. Gastroenterology & hepatology

10 September 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28404137 AND SRC:MED&resulttype=core&format=json

5 June 2020

volume

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28404137 AND SRC:MED&resulttype=core&format=json

5 June 2020

issue

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28404137 AND SRC:MED&resulttype=core&format=json

5 June 2020

page(s)

224-234

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28404137 AND SRC:MED&resulttype=core&format=json

Mapping of a susceptibility locus for Crohn's disease on chromosome 16

5 June 2020

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Genetics of inflammatory bowel disease: progress and prospects

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On the allelic spectrum of human disease

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The future of genetic studies of complex human diseases

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Association study designs for complex diseases

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Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease

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A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

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Common variants at five new loci associated with early-onset inflammatory bowel disease

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Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease

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Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4

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Genome-wide association identifies multiple ulcerative colitis susceptibility loci

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Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease

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7 January 2021

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

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7 January 2021

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

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7 January 2021

Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study

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Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

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7 January 2021

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

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7 January 2021

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

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7 January 2021

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

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7 January 2021

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

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7 January 2021

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

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7 January 2021

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.

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7 January 2021

Understanding inflammatory bowel disease via immunogenetics

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7 January 2021

Estimation and partitioning of (co)heritability of inflammatory bowel disease from GWAS and immunochip data

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7 January 2021

Gene expression profiling of CD8 T cells predicts prognosis in patients with Crohn disease and ulcerative colitis

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7 January 2021

Accounting for eXentricities: analysis of the X chromosome in GWAS reveals X-linked genes implicated in autoimmune diseases

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7 January 2021

Genetic studies of Crohn's disease: past, present and future

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7 January 2021

Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci

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7 January 2021

High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

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7 January 2021

Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease

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7 January 2021

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

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7 January 2021

Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis

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7 January 2021

Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes

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7 January 2021

Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7.

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7 January 2021

Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition

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Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease

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Predictive value of the CARD15 variant 1007fs for the diagnosis of intestinal stenoses and the need for surgery in Crohn's disease in clinical practice: results of a prospective study

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Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing

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A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3.

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NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

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IL23R (Interleukin 23 Receptor) Variants Protective against Inflammatory Bowel Diseases (IBD) Display Loss of Function due to Impaired Protein Stability and Intracellular Trafficking

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Systematic localization of common disease-associated variation in regulatory DNA

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Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway

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Genetic risk prediction in complex disease

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Diagnosis of Parkinson's disease on the basis of clinical and genetic classification: a population-based modelling study

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Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

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7 January 2021

Monogenic diseases associated with intestinal inflammation: implications for the understanding of inflammatory bowel disease

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7 January 2021

The diagnostic approach to monogenic very early onset inflammatory bowel disease

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7 January 2021

Targeted gene panel sequencing in children with very early onset inflammatory bowel disease--evaluation and prospective analysis.

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7 January 2021

Clinical, serological and genetic predictors of inflammatory bowel disease course

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7 January 2021

The molecular classification of the clinical manifestations of Crohn's disease

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7 January 2021

Diverse effects of the CARD15 and IBD5 loci on clinical phenotype in 630 patients with Crohn's disease

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7 January 2021

Genotype/phenotype analyses for 53 Crohn's disease associated genetic polymorphisms

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7 January 2021

CARD15 genetic variation in a Quebec population: prevalence, genotype-phenotype relationship, and haplotype structure

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7 January 2021

Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease

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7 January 2021

The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease

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7 January 2021

Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis.

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7 January 2021

Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: a cohort study

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7 January 2021

Predicting Outcomes to Optimize Disease Management in Inflammatory Bowel Diseases

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7 January 2021

MicroRNAs Classify Different Disease Behavior Phenotypes of Crohn's Disease and May Have Prognostic Utility

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7 January 2021

Extra-Gastrointestinal Manifestations of Inflammatory Bowel Disease May Be Less Common Than Previously Reported

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7 January 2021

Rheumatic manifestations in inflammatory bowel diseases: a link between GI and rheumatology

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Clinical, serologic, and genetic factors associated with pyoderma gangrenosum and erythema nodosum in inflammatory bowel disease patients

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7 January 2021

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.

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7 January 2021

Mongersen, an oral SMAD7 antisense oligonucleotide, and Crohn's disease

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7 January 2021

Ustekinumab as Induction and Maintenance Therapy for Crohn’s Disease

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7 January 2021

Inflammatory bowel disease and mutations affecting the interleukin-10 receptor

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7 January 2021

Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer

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7 January 2021

Cost-effectiveness of thiopurine methyltransferase genotype screening in patients about to commence azathioprine therapy for treatment of inflammatory bowel disease

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7 January 2021

A common missense variant in NUDT15 confers susceptibility to thiopurine-induced leukopenia

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7 January 2021

Thiopurine methyltransferase (TPMT) genotyping to predict myelosuppression risk

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7 January 2021

HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants.

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7 January 2021

Predictive model for the outcome of infliximab therapy in Crohn's disease based on apoptotic pharmacogenetic index and clinical predictors

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7 January 2021

A Matrix-based Model Predicts Primary Response to Infliximab in Crohn's Disease

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7 January 2021

Mucosal gene signatures to predict response to infliximab in patients with ulcerative colitis.

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7 January 2021

Predictive value of epithelial gene expression profiles for response to infliximab in Crohn's disease.

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7 January 2021

Pharmacokinetics of anti-TNF monoclonal antibodies in inflammatory bowel disease: Adding value to current practice

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7 January 2021

Influence of the HLA-DRB1 Genotype on Antibody Development to Interferon Beta in Multiple Sclerosis

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Immunogenicity to infliximab is associated with HLA-DRB1.

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7 January 2021

Characteristics of Skin Lesions Associated With Anti-Tumor Necrosis Factor Therapy in Patients With Inflammatory Bowel Disease: A Cohort Study

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7 January 2021

Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment

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7 January 2021

A microbial signature for Crohn's disease

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7 January 2021

A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis

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7 January 2021